Published in PLoS Genet on August 15, 2013
Multi-ethnic fine-mapping of 14 central adiposity loci. Hum Mol Genet (2014) 0.98
The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease. Hum Mol Genet (2014) 0.89
Gender-specific association between tobacco smoking and central obesity among 0.5 million Chinese people: the China Kadoorie Biobank Study. PLoS One (2015) 0.88
Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study. Am J Hypertens (2014) 0.86
Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat. Int J Obes (Lond) (2015) 0.86
Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. Public Health Genomics (2014) 0.84
Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity. Dev Cell (2015) 0.82
Effects of Obesity Related Genetic Variations on Visceral and Subcutaneous Fat Distribution in a Chinese Population. Sci Rep (2016) 0.82
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits. Curr Diab Rep (2015) 0.81
Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study. PLoS One (2016) 0.79
Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Sci Rep (2016) 0.79
Signatures of archaic adaptive introgression in present-day human populations. Mol Biol Evol (2016) 0.79
Archaic Adaptive Introgression in TBX15/WARS2. Mol Biol Evol (2017) 0.78
Genome-wide QTL mapping of nine body composition and bone mineral density traits in pigs. Genet Sel Evol (2014) 0.78
The Genetics of Pediatric Obesity. Trends Endocrinol Metab (2015) 0.78
Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations. Int J Obes (Lond) (2016) 0.77
A genome-wide investigation of food addiction. Obesity (Silver Spring) (2016) 0.77
Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families. Clin Epigenetics (2016) 0.77
Interleukin-6 gene polymorphisms, dietary fat intake, obesity and serum lipid concentrations in black and white South African women. Nutrients (2014) 0.77
A family-based joint test for mean and variance heterogeneity for quantitative traits. Ann Hum Genet (2014) 0.77
Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41. Nat Commun (2016) 0.77
Obesity and genomics: role of technology in unraveling the complex genetic architecture of obesity. Hum Genet (2015) 0.77
Genome-wide association study on legendre random regression coefficients for the growth and feed intake trajectory on Duroc Boars. BMC Genet (2015) 0.77
Genome-wide association study for the interaction between BMR and BMI in obese Korean women including overweight. Nutr Res Pract (2015) 0.76
Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. Genet Epidemiol (2016) 0.76
Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis. PLoS Genet (2016) 0.76
Genome-wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions. Mol Biol Evol (2017) 0.75
Sexual Dimorphisms in Genetic Loci Linked to Body Fat Distribution. Biosci Rep (2017) 0.75
A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS). PLoS One (2015) 0.75
Genomic Evidence for Bacterial Determinants Influencing Obesity Development. Int J Environ Res Public Health (2017) 0.75
Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. Am J Hum Genet (2016) 0.75
Association of ADIPOQ gene with type 2 diabetes and related phenotypes in African American men and women: the Jackson Heart Study. BMC Genet (2015) 0.75
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun (2016) 0.75
Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians. Diabetologia (2015) 0.75
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genet (2017) 0.75
Genomic control for association studies. Biometrics (1999) 64.39
Prevalence and trends in obesity among US adults, 1999-2008. JAMA (2010) 50.58
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
General and abdominal adiposity and risk of death in Europe. N Engl J Med (2008) 14.49
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet (2011) 6.36
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Genomic inflation factors under polygenic inheritance. Eur J Hum Genet (2011) 4.89
Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J Clin Invest (1983) 4.70
Associations of general and abdominal obesity with multiple health outcomes in older women: the Iowa Women's Health Study. Arch Intern Med (2000) 4.36
The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913. Diabetes (1985) 4.23
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet (2011) 3.92
Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat Genet (2008) 3.24
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors. J Clin Endocrinol Metab (2003) 3.01
Estimating coverage and power for genetic association studies using near-complete variation data. Nat Genet (2008) 2.80
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet (2010) 2.76
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study. J Clin Endocrinol Metab (2010) 2.37
Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors. Am J Clin Nutr (2005) 2.30
Selection of anthropometric indicators for classification of abdominal fatness--a critical review. Int J Obes Relat Metab Disord (1998) 2.17
Trends in waist circumference among U.S. adults. Obes Res (2003) 2.01
Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring) (2009) 1.88
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet (2012) 1.84
Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association. Hum Mol Genet (2011) 1.83
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet (2011) 1.60
Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities. Diabetologia (2007) 1.56
Distribution of body fat and risk of coronary heart disease in men and women. Curr Opin Cardiol (2008) 1.53
Genetic and behavioral determinants of waist-hip ratio and waist circumference in women twins. Obes Res (1998) 1.53
Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab (2012) 1.44
Genetic and behavioral influences on body fat distribution. Int J Obes (1990) 1.43
Waist circumference, visceral obesity, and cardiovascular risk. J Cardiopulm Rehabil (2003) 1.43
Quantifying the underestimation of relative risks from genome-wide association studies. PLoS Genet (2011) 1.30
Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia (2012) 1.03
Genotype-phenotype correlations of PCOS susceptibility SNPs identified by GWAS in a large cohort of Han Chinese women. Hum Reprod (2012) 1.00
Ras responsive element binding protein-1 (RREB-1) down-regulates hZIP1 expression in prostate cancer cells. Prostate (2010) 1.00
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. PLoS Genet (2012) 1.00
Lhx2 expression promotes self-renewal of a distinct multipotential hematopoietic progenitor cell in embryonic stem cell-derived embryoid bodies. PLoS One (2008) 0.94
Assessing the impact of global versus local ancestry in association studies. BMC Proc (2009) 0.91
Sensitivity of fluorescence in situ hybridization for melanoma diagnosis using RREB1, MYB, Cep6, and 11q13 probes in melanoma subtypes. Arch Dermatol (2010) 0.91
RREB1 transcription factor splice variants in urologic cancer. Am J Pathol (2011) 0.87
Genetic and environmental influences on body-fat measures among African-American twins. Obes Res (2002) 0.85
Genetic and environmental influences on waist-to-hip ratio and waist circumference in an older Swedish twin population. Int J Obes Relat Metab Disord (1999) 0.81
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37
Finding the missing heritability of complex diseases. Nature (2009) 67.95
The structure of haplotype blocks in the human genome. Science (2002) 50.88
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol (2002) 35.63
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA (2006) 24.01
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med (2006) 23.83
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med (2015) 19.14
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res (2007) 19.07
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med (2005) 17.32
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Characterizing the cancer genome in lung adenocarcinoma. Nature (2007) 16.48
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med (2006) 16.17
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet (2007) 14.37
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care (2007) 14.35
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
The reasons for geographic and racial differences in stroke study: objectives and design. Neuroepidemiology (2005) 13.05
Many sequence variants affecting diversity of adult human height. Nat Genet (2008) 12.80
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet (2008) 12.43
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22