Published in Nature on August 25, 2013
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments. Genome Res (2013) 2.05
Formation of Chromosomal Domains by Loop Extrusion. Cell Rep (2016) 1.60
Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion. Mol Cell (2014) 1.58
Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat Struct Mol Biol (2014) 1.30
SMC complexes: from DNA to chromosomes. Nat Rev Mol Cell Biol (2016) 1.07
Chromosomes Progress to Metaphase in Multiple Discrete Steps via Global Compaction/Expansion Cycles. Cell (2015) 0.99
Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres. EMBO J (2013) 0.97
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Structural Basis and IP6 Requirement for Pds5-Dependent Cohesin Dynamics. Mol Cell (2016) 0.96
ROCC, a conserved region in cohesin's Mcd1 subunit, is essential for the proper regulation of the maintenance of cohesion and establishment of condensation. Mol Biol Cell (2014) 0.96
Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation. Curr Biol (2014) 0.96
Complex elaboration: making sense of meiotic cohesin dynamics. FEBS J (2015) 0.93
Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion. EMBO J (2014) 0.91
Arabidopsis thaliana WAPL is essential for the prophase removal of cohesin during meiosis. PLoS Genet (2014) 0.88
Structure and function of cohesin's Scc3/SA regulatory subunit. FEBS Lett (2014) 0.88
Architectural proteins, transcription, and the three-dimensional organization of the genome. FEBS Lett (2015) 0.87
Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome. BMC Genomics (2016) 0.86
Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana. Mol Cell Proteomics (2015) 0.86
Cohesin gene mutations in tumorigenesis: from discovery to clinical significance. BMB Rep (2014) 0.85
Oocyte development, meiosis and aneuploidy. Semin Cell Dev Biol (2015) 0.83
A genetic screen for functional partners of condensin in fission yeast. G3 (Bethesda) (2014) 0.83
Initiation and maintenance of pluripotency gene expression in the absence of cohesin. Genes Dev (2015) 0.83
Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl. Nature (2017) 0.82
Cohesin mutations in human cancer. Biochim Biophys Acta (2016) 0.81
Sororin actively maintains sister chromatid cohesion. EMBO J (2016) 0.80
SMC complexes link gene expression and genome architecture. Curr Opin Genet Dev (2014) 0.80
Sister chromatid resolution is an intrinsic part of chromosome organization in prophase. Nat Cell Biol (2016) 0.80
Evidence for cohesin sliding along budding yeast chromosomes. Open Biol (2016) 0.78
Structural Insights into Ring Formation of Cohesin and Related Smc Complexes. Trends Cell Biol (2016) 0.78
Chromosome biology: Wapl spreads its wings. Curr Biol (2013) 0.77
Cohesin Can Remain Associated with Chromosomes during DNA Replication. Cell Rep (2017) 0.76
Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes. Elife (2016) 0.76
The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing. Epigenetics Chromatin (2016) 0.76
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High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress. PLoS One (2016) 0.75
Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse. Cell Rep (2016) 0.75
Chromosomes: Architectural cohesin. Nat Rev Mol Cell Biol (2013) 0.75
Cohesin's role in pluripotency and reprogramming. Cell Cycle (2015) 0.75
Cohesin acetylation and Wapl-Pds5 oppositely regulate translocation of cohesin along DNA. EMBO J (2016) 0.75
The Opposing Actions of Arabidopsis CHROMOSOME TRANSMISSION FIDELITY7 and WINGS APART-LIKE1 and 2 Differ in Mitotic and Meiotic Cells. Plant Cell (2016) 0.75
Separase Is Required for Homolog and Sister Disjunction during Drosophila melanogaster Male Meiosis, but Not for Biorientation of Sister Centromeres. PLoS Genet (2016) 0.75
Scc2/Nipbl hops between chromosomal cohesin rings after loading. Elife (2017) 0.75
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Mediator and cohesin connect gene expression and chromatin architecture. Nature (2010) 14.34
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BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods (2008) 6.51
Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell (2013) 6.37
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. Nature (2009) 5.96
Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell (2000) 5.10
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Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. Cell (2003) 4.63
Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J (2008) 4.28
Wapl controls the dynamic association of cohesin with chromatin. Cell (2006) 3.83
The cohesin ring concatenates sister DNA molecules. Nature (2008) 3.58
Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science (2001) 3.35
The cohesin complex and its roles in chromosome biology. Genes Dev (2008) 3.33
Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet (2009) 3.25
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Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Curr Biol (2006) 3.14
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A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature (2011) 2.58
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster. EMBO J (2009) 2.56
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Structure and dynamics of human interphase chromosome territories in vivo. Hum Genet (1998) 2.39
Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell (2010) 2.12
Cohesin's concatenation of sister DNAs maintains their intertwining. Mol Cell (2011) 1.91
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Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. Curr Biol (2007) 1.79
Cohesin's DNA exit gate is distinct from its entrance gate and is regulated by acetylation. Cell (2012) 1.75
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The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase. J Cell Biol (2006) 1.39
The genomic landscape of cohesin-associated chromatin interactions. Genome Res (2013) 1.36
Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. J Cell Sci (2010) 1.28
New insights into the formation and resolution of ultra-fine anaphase bridges. Semin Cell Dev Biol (2011) 1.27
Budding yeast Wapl controls sister chromatid cohesion maintenance and chromosome condensation. Curr Biol (2012) 1.24
Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gate. EMBO J (2013) 1.19
Overall Cdk activity modulates the DNA damage response in mammalian cells. J Cell Biol (2009) 1.14
Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells. Chromosome Res (2001) 1.07
Cohesin-independent segregation of sister chromatids in budding yeast. Mol Biol Cell (2011) 1.06
Cohesin and chromatin organisation. Curr Opin Genet Dev (2011) 1.06
Separase is recruited to mitotic chromosomes to dissolve sister chromatid cohesion in a DNA-dependent manner. Cell (2009) 1.04
Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage. Mol Cancer (2010) 0.87
Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature (2008) 12.01
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol (2003) 8.32
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell (2009) 6.89
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (2006) 6.64
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The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr Biol (2007) 6.17
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods (2006) 5.96
Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med (2011) 5.66
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr Biol (2007) 5.17
High-throughput RNAi screening by time-lapse imaging of live human cells. Nat Methods (2006) 4.86
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (2010) 4.69
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell (2010) 4.69
Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Mol Cell (2003) 4.67
The quantitative proteome of a human cell line. Mol Syst Biol (2011) 4.57
Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature (2005) 4.57
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation. PLoS Biol (2004) 4.23
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Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. Dev Cell (2008) 4.01
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol Cell (2007) 3.86
Wapl controls the dynamic association of cohesin with chromatin. Cell (2006) 3.83
Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol (2005) 3.72
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell (2010) 3.70
Visualization of image data from cells to organisms. Nat Methods (2010) 3.66
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Cell (2002) 3.64
Mapping the dynamic organization of the nuclear pore complex inside single living cells. Nat Cell Biol (2004) 3.62
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Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol (2005) 3.33
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Global chromosome positions are transmitted through mitosis in mammalian cells. Cell (2003) 3.27
Automatic identification of subcellular phenotypes on human cell arrays. Genome Res (2004) 3.25
Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet (2009) 3.25
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Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat Struct Mol Biol (2007) 3.13
High-throughput fluorescence microscopy for systems biology. Nat Rev Mol Cell Biol (2006) 3.08
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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol (2009) 2.98
Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. J Cell Biol (2002) 2.97
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Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol (2010) 2.91
Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes. Cell (2011) 2.89
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin. EMBO J (2009) 2.78
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Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell (2007) 2.72
TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Curr Biol (2003) 2.71
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science (2009) 2.69
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SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells. Dev Cell (2009) 2.57
Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication. Curr Biol (2006) 2.47
A contractile nuclear actin network drives chromosome congression in oocytes. Nature (2005) 2.45
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Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. Curr Biol (2006) 2.04
Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase. Nat Cell Biol (2007) 2.00
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