Published in Cancer Res on September 05, 2013
A new era of secreted phospholipase A₂. J Lipid Res (2015) 1.08
Membranous nephropathy: from models to man. J Clin Invest (2014) 1.05
Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape. Oncogene (2015) 0.83
Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth. Oncotarget (2014) 0.82
Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease. Biochem Pharmacol (2014) 0.82
Caspase-2 regulates oncogene-induced senescence. Oncotarget (2014) 0.81
The Role of STAT3 in Thyroid Cancer. Cancers (Basel) (2014) 0.80
Epigenetic control of phospholipase A2 receptor expression in mammary cancer cells. BMC Cancer (2015) 0.80
Role of the phospholipase A2 receptor in liposome drug delivery in prostate cancer cells. Mol Pharm (2014) 0.78
Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) (2015) 0.76
The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action. Oncogene (2016) 0.75
Phospholipase A2 Receptor Gene Polymorphisms Alter its Functions and Present a Genetic Risk of an Increased Intima-Media Thickness of the Carotid Artery. J Atheroscler Thromb (2016) 0.75
Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC Cancer (2016) 0.75
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med (2009) 11.81
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (2007) 9.86
Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One (2008) 8.97
Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell (2008) 7.65
Metastasis: a question of life or death. Nat Rev Cancer (2006) 6.26
Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell (2008) 5.88
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature (2008) 5.32
Retracted Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol (2009) 3.84
Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab (2011) 3.35
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res (2009) 3.31
Polycomb CBX7 has a unifying role in cellular lifespan. Nat Cell Biol (2003) 2.96
Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J (2004) 2.94
A high glycolytic flux supports the proliferative potential of murine embryonic stem cells. Antioxid Redox Signal (2007) 2.77
Prostate cancer diagnosis: multiparametric MR-targeted biopsy with cognitive and transrectal US-MR fusion guidance versus systematic biopsy--prospective multicenter study. Radiology (2013) 2.47
A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma. Cancer Cell (2013) 2.46
Role of magnetic resonance imaging before initial biopsy: comparison of magnetic resonance imaging-targeted and systematic biopsy for significant prostate cancer detection. BJU Int (2011) 2.41
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PLoS One (2009) 2.23
Dynamic contrast-enhanced-magnetic resonance imaging evaluation of intraprostatic prostate cancer: correlation with radical prostatectomy specimens. Urology (2009) 2.16
Real-time PCR based on SYBR-Green I fluorescence: an alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions. BMC Biotechnol (2003) 2.05
Role of polycomb group proteins in stem cell self-renewal and cancer. DNA Cell Biol (2005) 1.89
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. J Lipid Res (2010) 1.82
Human telomeric position effect is determined by chromosomal context and telomeric chromatin integrity. EMBO Rep (2002) 1.79
Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects. Am J Hum Genet (2007) 1.73
Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells. Cancer Cell (2004) 1.71
Endoluminal occlusion of the inferior vena cava in renal cell carcinoma with retro- or suprahepatic caval thrombus. BJU Int (2006) 1.71
Development of a standardized ELISA for the determination of autoantibodies against human M-type phospholipase A2 receptor in primary membranous nephropathy. Clin Chim Acta (2013) 1.68
Peripheral zone prostate cancers: location and intraprostatic patterns of spread at histopathology. Prostate (2009) 1.66
Weiss system revisited: a clinicopathologic and immunohistochemical study of 49 adrenocortical tumors. Am J Surg Pathol (2002) 1.60
Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor. Biochemistry (2007) 1.56
Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas. PLoS Genet (2009) 1.55
miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1. PLoS Genet (2013) 1.53
Influence of neuroblastoma stage on serum-based detection of MYCN amplification. Pediatr Blood Cancer (2009) 1.49
Prognostic value of microRNA expression pattern in upper tract urothelial carcinoma. BJU Int (2014) 1.49
EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. PLoS Genet (2012) 1.47
Gadd45a activation protects melanoma cells from ultraviolet B-induced apoptosis. J Invest Dermatol (2007) 1.47
Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res (2002) 1.45
A p21/WAF1 mutation favors the appearance of drug resistance to paclitaxel in human noncancerous epithelial mammary cells. Int J Cancer (2006) 1.44
Lipoprotein-associated and secreted phospholipases A₂ in cardiovascular disease: roles as biological effectors and biomarkers. Circulation (2010) 1.44
MSH2 in contrast to MLH1 and MSH6 is frequently inactivated by exonic and promoter rearrangements in hereditary nonpolyposis colorectal cancer. Cancer Res (2002) 1.41
Rapidly destructive osteoarthritis of the hip: MR imaging findings. AJR Am J Roentgenol (2002) 1.39
Netrin-1 acts as a survival factor for aggressive neuroblastoma. J Exp Med (2009) 1.36
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer. Cancer Cell (2013) 1.35
Bactericidal properties of human and murine groups I, II, V, X, and XII secreted phospholipases A(2). J Biol Chem (2001) 1.34
The CD10 enzyme is a key player to identify and regulate human mammary stem cells. Stem Cells (2010) 1.34
Regulation of ploidy and senescence by the AMPK-related kinase NUAK1. EMBO J (2009) 1.33
Immortalization of primary human prostate epithelial cells by c-Myc. Cancer Res (2005) 1.30
Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival. Clin Cancer Res (2011) 1.30
The M-type receptor PLA2R regulates senescence through the p53 pathway. EMBO Rep (2009) 1.29
Schwannoma of the sinonasal tract: a clinicopathologic and immunohistochemical study of 5 cases. Arch Pathol Lab Med (2003) 1.28
Increased circulating miR-21 levels are associated with kidney fibrosis. PLoS One (2013) 1.27
Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells. Cancer Res (2010) 1.27
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet (2007) 1.27
Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression. Cancer Res (2012) 1.26
Alterations of anaphase-promoting complex genes in human colon cancer cells. Oncogene (2003) 1.25
Systematic mRNA analysis for the effect of MLH1 and MSH2 missense and silent mutations on aberrant splicing. Hum Mutat (2006) 1.25
The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. J Physiol (2005) 1.24
MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression. Cancer Res (2009) 1.24
Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels. Protein Sci (2003) 1.23
Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11. Nat Clin Pract Neurol (2007) 1.22
MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells. BMC Genomics (2013) 1.21
Cancer stem cells: the emerging challenge of drug targeting. Curr Med Chem (2009) 1.17
Combined multiparametric MRI and targeted biopsies improve anterior prostate cancer detection, staging, and grading. Urology (2011) 1.15
Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases. J Neuropathol Exp Neurol (2002) 1.14
p53 as a target for anti-cancer drug development. Crit Rev Oncol Hematol (2006) 1.14
Emerging roles of secreted phospholipase A(2) enzymes: an update. Biochimie (2012) 1.14
A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis. EMBO Mol Med (2010) 1.13
PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro. Dev Biol (2003) 1.13
Transition zone and anterior stromal prostate cancers: zone of origin and intraprostatic patterns of spread at histopathology. Prostate (2009) 1.11
BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood (2008) 1.10
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice. Biochimie (2010) 1.10
Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol (2011) 1.10
Mitochondria and reactive oxygen species in renal cancer. Biochimie (2007) 1.08
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators. J Exp Med (2013) 1.08
Early postoperative peripheral blood reverse transcription PCR assay for prostate-specific antigen is associated with prostate cancer progression in patients undergoing radical prostatectomy. Cancer Res (2003) 1.07
Variation in prostate specific antigen results from 2 different assay platforms: clinical impact on 2304 patients undergoing prostate cancer screening. J Urol (2004) 1.07
A new role for the von Hippel-Lindau tumor suppressor protein: stimulation of mitochondrial oxidative phosphorylation complex biogenesis. Carcinogenesis (2004) 1.07
The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells. Mol Cancer Ther (2006) 1.05
Time-resolved fluoroimmunoassays of the complete set of secreted phospholipases A2 in human serum. Biochim Biophys Acta (2005) 1.05
Mutational characterization of individual breast tumors: TP53 and PI3K pathway genes are frequently and distinctively mutated in different subtypes. Breast Cancer Res Treat (2011) 1.04
HIF and reactive oxygen species regulate oxidative phosphorylation in cancer. Carcinogenesis (2008) 1.03
Neurofibromatosis type 1 gene as a mutational target in a mismatch repair-deficient cell type. Hum Genet (2002) 1.03
Two cutinase-like proteins secreted by Mycobacterium tuberculosis show very different lipolytic activities reflecting their physiological function. FASEB J (2010) 1.02
PTEN is a potent suppressor of small cell lung cancer. Mol Cancer Res (2014) 1.02
In vivo protective role of human group IIa phospholipase A2 against experimental anthrax. J Immunol (2005) 1.02
Circulating MYCN DNA as a tumor-specific marker in neuroblastoma patients. Cancer Res (2002) 1.02