Promising systemic immunotherapies in head and neck squamous cell carcinoma.

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Published in Oral Oncol on October 11, 2013

Authors

Neil Gildener-Leapman1, Robert L Ferris, Julie E Bauman

Author Affiliations

1: Department of Otolaryngology, University of Pittsburgh Eye and Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, United States.

Associated clinical trials:

Safety Study of HPV DNA Vaccine to Treat Head and Neck Cancer Patients | NCT01493154

Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck | NCT01836029

TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck | NCT01334177

A Safety and Efficacy Study of Siltuximab (CNTO 328) in Male Subjects With Metastatic Hormone-Refractory Prostate Cancer (HRPC) | NCT00385827

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | NCT00588770

A Study of Siltuximab (Anti- IL 6 Monoclonal Antibody) in Patients With High-risk Smoldering Multiple Myeloma | NCT01484275

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery | NCT01468896

A Phase 1 Dose Escalation Study of AV-203, an ERBB3 Inhibitory Antibody, in Subjects With Advanced Solid Tumors | NCT01603979

Vaccine Therapy in Treating Patients With Head and Neck Cancer | NCT00404339

Preoperative Treatment With Cetuximab and/or IMC-A12 | NCT00957853

NCT 01598792

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