Published in EMBO J on October 18, 2013
Interspecies interactions determine the impact of the gut microbiota on nutrient allocation in Drosophila melanogaster. Appl Environ Microbiol (2013) 1.48
The microenvironment of injured murine gut elicits a local pro-restitutive microbiota. Nat Microbiol (2016) 1.44
Role of DUOX in gut inflammation: lessons from Drosophila model of gut-microbiota interactions. Front Cell Infect Microbiol (2014) 1.03
Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches. Front Microbiol (2015) 0.97
Host-microbe interactions shaping the gastrointestinal environment. Trends Immunol (2014) 0.95
Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol (2015) 0.94
Bacteria-bacteria interactions within the microbiota of the ancestral metazoan Hydra contribute to fungal resistance. ISME J (2014) 0.93
Epithelial adhesion mediated by pilin SpaC is required for Lactobacillus rhamnosus GG-induced cellular responses. Appl Environ Microbiol (2014) 0.93
Redox signaling mediated by the gut microbiota. Free Radic Res (2013) 0.89
Approaches to studying and manipulating the enteric microbiome to improve autism symptoms. Microb Ecol Health Dis (2015) 0.89
Host Genetic Control of the Microbiota Mediates the Drosophila Nutritional Phenotype. Appl Environ Microbiol (2015) 0.87
Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins. J Mol Biol (2015) 0.87
Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway. Cell Rep (2015) 0.86
Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice. PLoS One (2014) 0.85
Antibiotics and the developing infant gut microbiota and resistome. Curr Opin Microbiol (2015) 0.85
Fermented dairy products modulate Citrobacter rodentium-induced colonic hyperplasia. J Infect Dis (2014) 0.84
Human pathogenic bacteria, fungi, and viruses in Drosophila: disease modeling, lessons, and shortcomings. Virulence (2014) 0.84
Comparative evaluation of the genomes of three common Drosophila-associated bacteria. Biol Open (2016) 0.84
Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine. Nutrients (2014) 0.83
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Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice. PLoS Pathog (2016) 0.82
Redox signaling mediates symbiosis between the gut microbiota and the intestine. Gut Microbes (2014) 0.81
Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia. Proc Natl Acad Sci U S A (2017) 0.80
The Influence of the Gut Microbiota on Host Physiology: In Pursuit of Mechanisms. Yale J Biol Med (2016) 0.80
The multi-tasking gut epithelium of insects. Insect Biochem Mol Biol (2015) 0.79
Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. J Clin Invest (2016) 0.79
Sepsis in preterm infants causes alterations in mucosal gene expression and microbiota profiles compared to non-septic twins. Sci Rep (2016) 0.78
Moderate dietary protein restriction alters the composition of gut microbiota and improves ileal barrier function in adult pig model. Sci Rep (2017) 0.77
Investigating the Effect of Different Treatments with Lactic Acid Bacteria on the Fate of Listeria monocytogenes and Staphylococcus aureus Infection in Galleria mellonella Larvae. PLoS One (2016) 0.77
Neutrophils and the inflammatory tissue microenvironment in the mucosa. Immunol Rev (2016) 0.77
Stimulating cROSstalk between commensal bacteria and intestinal stem cells. EMBO J (2013) 0.76
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Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration. Free Radic Biol Med (2016) 0.76
Intrinsic Defense Mechanisms of the Intestinal Epithelium. Cell Host Microbe (2016) 0.75
A Mesh-Duox pathway regulates homeostasis in the insect gut. Nat Microbiol (2017) 0.75
Stable Host Gene Expression in the Gut of Adult Drosophila melanogaster with Different Bacterial Mono-Associations. PLoS One (2016) 0.75
NADPH oxidase-1 deficiency offers little protection in Salmonella typhimurium-induced typhlitis in mice. World J Gastroenterol (2016) 0.75
Barcoded sequencing reveals diverse intrauterine microbiomes in patients suffering with endometrial polyps. Am J Transl Res (2016) 0.75
Type VI secretion system contributes to Enterohemorrhagic Escherichia coli virulence by secreting catalase against host reactive oxygen species (ROS). PLoS Pathog (2017) 0.75
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium. Redox Biol (2016) 0.75
Probiotics research in Galleria mellonella. Virulence (2015) 0.75
Probiotics and Innate and Adaptive Immune Responses in Premature Infants. For Immunopathol Dis Therap (2016) 0.75
Intestinal microbiota: a potential target for the treatment of postmenopausal osteoporosis. Bone Res (2017) 0.75
D-Alanylation of teichoic acids contributes to Lactobacillus plantarum-mediated Drosophila growth during chronic undernutrition. Nat Microbiol (2017) 0.75
The Research Progress on Intestinal Stem Cells and Its Relationship with Intestinal Microbiota. Front Immunol (2017) 0.75
The Gut Commensal Microbiome of Drosophila melanogaster Is Modified by the Endosymbiont Wolbachia. mSphere (2017) 0.75
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Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature (2005) 5.86
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Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation. Nature (2009) 4.26
A direct role for dual oxidase in Drosophila gut immunity. Science (2005) 4.24
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell Host Microbe (2009) 4.21
Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root. Cell (2010) 4.19
An antioxidant system required for host protection against gut infection in Drosophila. Dev Cell (2005) 3.14
Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing. Cell Metab (2011) 2.77
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Dev Cell (2008) 2.66
The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling. Nature (2008) 2.57
Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases. J Leukoc Biol (2004) 2.51
Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila. Cell (2013) 2.36
Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut. Cell Host Microbe (2012) 2.01
Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster. Environ Microbiol (2011) 1.94
A transient niche regulates the specification of Drosophila intestinal stem cells. Science (2010) 1.89
Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J (2007) 1.86
The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation. J Immunol (2009) 1.78
Hydrocyanines: a class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo. Angew Chem Int Ed Engl (2009) 1.69
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Over-expression of different aldehyde dehydrogenase genes in Arabidopsis thaliana confers tolerance to abiotic stress and protects plants against lipid peroxidation and oxidative stress. Plant Cell Environ (2006) 1.61
Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest (2012) 1.57
NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes. J Immunol (2003) 1.38
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci U S A (2011) 1.28
NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon. Mol Cell Biol (2010) 1.25
Enteric commensal bacteria induce extracellular signal-regulated kinase pathway signaling via formyl peptide receptor-dependent redox modulation of dual specific phosphatase 3. J Biol Chem (2011) 1.13
NOX enzymes and Toll-like receptor signaling. Semin Immunopathol (2008) 1.13
The molecular cloning and characterization of Drosophila melanogaster myosin-IA and myosin-IB. J Mol Biol (1994) 1.12
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Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine. FASEB J (2012) 1.10
Nox1-dependent superoxide production controls colon adenocarcinoma cell migration. Biochim Biophys Acta (2007) 1.10
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A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production. Chem Commun (Camb) (2011) 0.97
Prebiotics, probiotics, and dietary fiber in gastrointestinal disease. Gastroenterol Clin North Am (2007) 0.94
Reactive oxygen production induced by the gut microbiota: pharmacotherapeutic implications. Curr Med Chem (2012) 0.91
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Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (2003) 4.56
Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18
Superoxide production and expression of nox family proteins in human atherosclerosis. Circulation (2002) 3.95
Activation of beta-catenin by carcinogenic Helicobacter pylori. Proc Natl Acad Sci U S A (2005) 3.52
The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction. Mol Cell Biol (2004) 3.35
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation (2005) 3.12
Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury. Arterioscler Thromb Vasc Biol (2002) 3.10
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway. J Immunol (2002) 2.70
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy. Circ Res (2003) 2.50
Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella. J Immunol (2003) 2.43
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature (2004) 2.39
Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes. BMC Evol Biol (2007) 2.29
Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc Natl Acad Sci U S A (2002) 2.29
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J Clin Invest (2007) 2.22
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J Biol Chem (2011) 2.20
Increased Nox1 and hydrogen peroxide in prostate cancer. Prostate (2005) 2.19
The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation. Cancer Res (2004) 2.12
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol (2008) 2.07
Nox1-dependent reactive oxygen generation is regulated by Rac1. J Biol Chem (2006) 2.02
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol (2009) 2.01
Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. J Immunol (2002) 1.95
Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J (2007) 1.86
Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation. J Biol Chem (2005) 1.85
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal (2009) 1.80
The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation. J Immunol (2009) 1.78
Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am J Pathol (2006) 1.77
NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. Am J Physiol Cell Physiol (2003) 1.73
Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway Blockade. Cell Host Microbe (2008) 1.69
Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells. Antioxid Redox Signal (2009) 1.64
Bacterial activation of beta-catenin signaling in human epithelia. Am J Physiol Gastrointest Liver Physiol (2004) 1.60
Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chem Biol (2012) 1.60
Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis. Dev Biol (2002) 1.57
Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest (2012) 1.57
Activation of toll-like receptor 3 protects against DSS-induced acute colitis. Inflamm Bowel Dis (2007) 1.57
NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain. J Biol Chem (2003) 1.56
Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. Blood (2002) 1.54
Circuitry linking the Csr and stringent response global regulatory systems. Mol Microbiol (2011) 1.52
TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. J Immunol (2006) 1.50
Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways. Am J Physiol Gastrointest Liver Physiol (2005) 1.49
Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras. Int J Cancer (2008) 1.48
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J Clin Invest (2007) 1.47
Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation. Free Radic Biol Med (2009) 1.45
Cutting edge: bacterial modulation of epithelial signaling via changes in neddylation of cullin-1. J Immunol (2005) 1.40
Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited. Annu Rev Pathol (2013) 1.38
TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am J Physiol Gastrointest Liver Physiol (2003) 1.38
Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain. Biochemistry (2010) 1.38
Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease. Infect Immun (2008) 1.37
Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem (2010) 1.36
Identification and characterization of VPO1, a new animal heme-containing peroxidase. Free Radic Biol Med (2008) 1.33
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. Am J Physiol Heart Circ Physiol (2010) 1.31
Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals. Free Radic Biol Med (2010) 1.30
Nox3 regulation by NOXO1, p47phox, and p67phox. J Biol Chem (2004) 1.29
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci U S A (2011) 1.28
Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection. Hepatology (2010) 1.25
The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut. Pediatr Res (2008) 1.22
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxid Redox Signal (2006) 1.22
Redox regulation of interleukin-4 signaling. Immunity (2008) 1.20
Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation. Mol Microbiol (2010) 1.18
Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes. BMC Evol Biol (2007) 1.17
Nox4: a hydrogen peroxide-generating oxygen sensor. Biochemistry (2014) 1.14
Enteric commensal bacteria induce extracellular signal-regulated kinase pathway signaling via formyl peptide receptor-dependent redox modulation of dual specific phosphatase 3. J Biol Chem (2011) 1.13
Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest (2015) 1.13
Saturation mutagenesis of toluene ortho-monooxygenase of Burkholderia cepacia G4 for Enhanced 1-naphthol synthesis and chloroform degradation. Appl Environ Microbiol (2004) 1.13
Nox regulation of smooth muscle contraction. Free Radic Biol Med (2007) 1.09
Commensal-epithelial signaling mediated via formyl peptide receptors. Am J Pathol (2010) 1.08
Water-soluble superparamagnetic manganese ferrite nanoparticles for magnetic resonance imaging. Biomaterials (2010) 1.06
Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3. Gene (2005) 1.05
Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region. Mol Biol Cell (2008) 1.05
Beta defensin-1, parvalbumin, and vimentin: a panel of diagnostic immunohistochemical markers for renal tumors derived from gene expression profiling studies using cDNA microarrays. Am J Surg Pathol (2003) 1.05
Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity. Gut (2011) 1.05
Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi. Infect Immun (2006) 1.03
Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus. J Immunol (2005) 1.02
Inhibition of Jun N-terminal kinase (JNK) enhances glucocorticoid receptor-mediated function in mouse hippocampal HT22 cells. Neuropsychopharmacology (2005) 1.01
Review of methodologies and a protocol for the Agrobacterium-mediated transformation of wheat. Plant Methods (2005) 0.99
Cordycepin is an immunoregulatory active ingredient of Cordyceps sinensis. Am J Chin Med (2008) 0.97
Toll-like receptor 5-dependent regulation of inflammation in systemic Salmonella enterica Serovar typhimurium infection. Infect Immun (2009) 0.97
Visualisation of plastids in endosperm, pollen and roots of transgenic wheat expressing modified GFP fused to transit peptides from wheat SSU RubisCO, rice FtsZ and maize ferredoxin III proteins. Transgenic Res (2007) 0.97
Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response. J Biol Chem (2004) 0.96
Nox5 forms a functional oligomer mediated by self-association of its dehydrogenase domain. Biochemistry (2011) 0.96
Microbicidal activity of vascular peroxidase 1 in human plasma via generation of hypochlorous acid. Infect Immun (2012) 0.95
Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids (2011) 0.93
Recognition of bacterial pathogens and mucosal immunity. Cell Microbiol (2011) 0.93
The Salmonella effector AvrA mediates bacterial intracellular survival during infection in vivo. Cell Microbiol (2011) 0.92
Nox4 B-loop creates an interface between the transmembrane and dehydrogenase domains. J Biol Chem (2010) 0.88
Common aroma-active components of propolis from 23 regions of China. J Sci Food Agric (2010) 0.88