Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function.

PubWeight™: 1.14‹?› | Rank: Top 10%

🔗 View Article (PMC 3896087)

Published in J Immunol on October 23, 2013

Authors

Kevin J Esch1, Rachel Juelsgaard, Pedro A Martinez, Douglas E Jones, Christine A Petersen

Author Affiliations

1: Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, IA 50011.

Articles citing this

Leishmania infantum-specific production of IFN-γ and IL-10 in stimulated blood from dogs with clinical leishmaniosis. Parasit Vectors (2016) 1.41

Deception and manipulation: the arms of leishmania, a successful parasite. Front Immunol (2014) 0.93

Regulation of immunity during visceral Leishmania infection. Parasit Vectors (2016) 0.92

Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease. Immunity (2016) 0.88

Role of CD8(+) T cells in protection against Leishmania donovani infection in healed Visceral Leishmaniasis individuals. BMC Infect Dis (2014) 0.88

Lessons from other diseases: granulomatous inflammation in leishmaniasis. Semin Immunopathol (2015) 0.85

Induction of Inhibitory Receptors on T Cells During Plasmodium vivax Malaria Impairs Cytokine Production. J Infect Dis (2015) 0.84

Parasite load induces progressive spleen architecture breakage and impairs cytokine mRNA expression in Leishmania infantum-naturally infected dogs. PLoS One (2015) 0.81

CD8+ T Cell Exhaustion, Suppressed Gamma Interferon Production, and Delayed Memory Response Induced by Chronic Brucella melitensis Infection. Infect Immun (2015) 0.81

Immunologic progression of canine leishmaniosis following vertical transmission in United States dogs. Vet Immunol Immunopathol (2015) 0.80

Immunohistochemical Analysis of PD-L1 Expression in Canine Malignant Cancers and PD-1 Expression on Lymphocytes in Canine Oral Melanoma. PLoS One (2016) 0.80

Myeloid-derived suppressor cells impair alveolar macrophages through PD-1 receptor ligation during Pneumocystis pneumonia. Infect Immun (2014) 0.80

The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis. Front Immunol (2016) 0.79

The host-protective effect of arabinosylated lipoarabinomannan against Leishmania donovani infection is associated with restoration of IFN-γ responsiveness. PLoS One (2015) 0.78

Decreased PD-1/PD-L1 Expression Is Associated with the Reduction in Mucosal Immunoglobulin A in Mice with Intestinal Ischemia Reperfusion. Dig Dis Sci (2015) 0.78

A Mother's Gift: Congenital Transmission of Trypanosoma and Leishmania Species. PLoS Pathog (2016) 0.78

PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection. Proc Natl Acad Sci U S A (2016) 0.78

Evaluation of Costimulatory Molecules in Peripheral Blood Lymphocytes of Canine Patients with Histiocytic Sarcoma. PLoS One (2016) 0.77

Insights on adaptive and innate immunity in canine leishmaniosis. Parasitology (2016) 0.77

Regulatory IgDhi B Cells Suppress T Cell Function via IL-10 and PD-L1 during Progressive Visceral Leishmaniasis. J Immunol (2016) 0.77

Recovery of antigen-specific T cell responses from dogs infected with Leishmania (L.) infantum by use of vaccine associated TLR-agonist adjuvant. Vaccine (2016) 0.76

Combined Immune Therapy for the Treatment of Visceral Leishmaniasis. PLoS Negl Trop Dis (2016) 0.76

Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory Molecules. Front Immunol (2016) 0.76

Immune exhaustion during chronic infections in cattle. J Vet Med Sci (2016) 0.75

Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasis. Parasit Vectors (2015) 0.75

Case Report: No Response to Liposomal Daunorubicin in a Patient with Drug-Resistant HIV-Associated Visceral Leishmaniasis. PLoS Negl Trop Dis (2015) 0.75

Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease. Front Immunol (2017) 0.75

Splenic CD4+ T Cells in Progressive Visceral Leishmaniasis Show a Mixed Effector-Regulatory Phenotype and Impair Macrophage Effector Function through Inhibitory Receptor Expression. PLoS One (2017) 0.75

Leishmanicidal Activity of Piper nigrum Bioactive Fractions is Interceded via Apoptosis In Vitro and Substantiated by Th1 Immunostimulatory Potential In Vivo. Front Microbiol (2015) 0.75

The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani. Clin Transl Immunology (2017) 0.75

Articles cited by this

Restoring function in exhausted CD8 T cells during chronic viral infection. Nature (2005) 28.04

Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med (1998) 14.39

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol (2003) 11.48

T cell exhaustion. Nat Immunol (2011) 11.08

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol (2007) 7.36

Memory CD8 T-cell differentiation during viral infection. J Virol (2004) 6.75

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol (2004) 4.58

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med (2010) 3.81

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection. J Exp Med (2007) 3.05

Leishmaniasis: complexity at the host-pathogen interface. Nat Rev Microbiol (2011) 2.93

Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis. J Exp Med (2007) 2.75

Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. J Exp Med (1999) 2.51

High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proc Natl Acad Sci U S A (2009) 2.42

Are senescence and exhaustion intertwined or unrelated processes that compromise immunity? Nat Rev Immunol (2011) 1.93

Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi. J Immunol (2001) 1.90

Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion. J Immunol (2005) 1.85

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proc Natl Acad Sci U S A (2011) 1.62

Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J Immunol (2009) 1.37

Role of iNOS in human host defense. Science (2006) 1.35

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade. Proc Natl Acad Sci U S A (2011) 1.34

IL-10 neutralization promotes parasite clearance in splenic aspirate cells from patients with visceral leishmaniasis. J Infect Dis (2011) 1.33

Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases. Sci Signal (2009) 1.32

B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections. PLoS Pathog (2009) 1.27

CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: the latter is reversed, in vitro, by TLR2 agonists. PLoS Negl Trop Dis (2010) 1.20

Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis. J Immunol (2010) 1.14

Visceral leishmaniasis: immunology and prospects for a vaccine. Clin Microbiol Infect (2011) 1.12

Immunologic indicators of clinical progression during canine Leishmania infantum infection. Clin Vaccine Immunol (2009) 1.02

Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion? J Infect Dis (2008) 0.98

Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance. J Immunol (2008) 0.94

Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion. J Immunol (2013) 0.94

The TGF-beta response to Leishmania chagasi in the absence of IL-12. Eur J Immunol (2002) 0.90

Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. J Immunol (2006) 0.89

Preventing zoonotic canine leishmaniasis in northeastern Brazil: pet attachment and adoption of community Leishmania prevention. Am J Trop Med Hyg (2012) 0.85

Canine leishmaniasis in Southern Italy: a role for nitric oxide released from activated macrophages in asymptomatic infection? Parasit Vectors (2008) 0.80

Articles by these authors

Assessment of owner willingness to treat or manage diseases of dogs and cats as a guide to shelter animal adoptability. J Am Vet Med Assoc (2013) 1.98

Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2007) 1.92

Novel PI 3-kinase-dependent mechanisms of trypanosome invasion and vacuole maturation. J Cell Sci (2003) 1.40

Transmission and epidemiology of zoonotic protozoal diseases of companion animals. Clin Microbiol Rev (2013) 1.23

Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxide. Am J Trop Med Hyg (2007) 1.20

Disseminated Leishmania infantum infection in two sibling foxhounds due to possible vertical transmission. Can Vet J (2008) 1.04

Immunologic indicators of clinical progression during canine Leishmania infantum infection. Clin Vaccine Immunol (2009) 1.02

Activation parameters for heme-NO binding in alcaligenes xylosoxidans cytochrome c': the putative dinitrosyl intermediate forms via a dissociative mechanism. J Am Chem Soc (2009) 0.98

CD4+ Th1 cells induced by dendritic cell-based immunotherapy in mice chronically infected with Leishmania amazonensis do not promote healing. Infect Immun (2004) 0.96

Parameter estimation and sensitivity analysis in an agent-based model of Leishmania major infection. J Theor Biol (2009) 0.93

Antigen-responsive CD4+ T cells from C3H mice chronically infected with Leishmania amazonensis are impaired in the transition to an effector phenotype. Infect Immun (2006) 0.92

Protection of C3HeB/FeJ mice against Leishmania amazonensis challenge after previous Leishmania major infection. Am J Trop Med Hyg (2004) 0.91

Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins. Proc Natl Acad Sci U S A (2011) 0.90

Soluble factors from Leishmania major-specific CD4+T cells and B cells limit L. amazonensis amastigote survival within infected macrophages. Microbes Infect (2006) 0.89

Synthesis of multivalent tuberculosis and Leishmania-associated capping carbohydrates reveals structure-dependent responses allowing immune evasion. J Am Chem Soc (2010) 0.88

The immunology of Leishmania infection and the implications for vaccine development. Ann N Y Acad Sci (2004) 0.87

A deficiency in the B cell response of C57BL/6 mice correlates with loss of macrophage-mediated killing of Leishmania amazonensis. Int J Parasitol (2009) 0.86

Preventing zoonotic canine leishmaniasis in northeastern Brazil: pet attachment and adoption of community Leishmania prevention. Am J Trop Med Hyg (2012) 0.85

A distal pocket Leu residue inhibits the binding of O2 and NO at the distal heme site of cytochrome c'. J Am Chem Soc (2012) 0.85

Inflammation in response to n3 fatty acids in a porcine obesity model. Comp Med (2012) 0.84

Promotion of a functional B cell germinal center response after Leishmania species co-infection is associated with lesion resolution. Am J Pathol (2012) 0.84

Failure of antigen-stimulated gammadelta T cells and CD4+ T cells from sensitized cattle to upregulate nitric oxide and mycobactericidal activity of autologous Mycobacterium avium subsp. paratuberculosis-infected macrophages. Vet Immunol Immunopathol (2007) 0.83

Alloimmune neonatal neutropenia and neonatal isoerythrolysis in a Thoroughbred colt. J Vet Diagn Invest (2011) 0.82

Pathogen-derived oligosaccharides improve innate immune response to intracellular parasite infection. Am J Pathol (2011) 0.82

Investigation of antigen-specific T-cell responses and subcutaneous granuloma development during experimental sensitization of calves with Mycobacterium avium subsp paratuberculosis. Am J Vet Res (2005) 0.81

Effect of endotoxic mastitis on epithelial cell numbers in the milk of dairy cows. Am J Vet Res (2009) 0.79

Chronic infection by Leishmania amazonensis mediated through MAPK ERK mechanisms. Immunol Res (2014) 0.78

Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions. Can J Vet Res (2009) 0.77

IL-2 limits IL-12 enhanced lymphocyte proliferation during Leishmania amazonensis infection. Cell Immunol (2011) 0.76

Neurological manifestations of human leishmaniasis. Handb Clin Neurol (2013) 0.76

The authors respond. J Am Vet Med Assoc (2013) 0.75

Vectorborne Transmission of Leishmania infantum from Hounds, United States. Emerg Infect Dis (2015) 0.75

Response to Dantas-Torres et al. Pet attachment and voluntary community participation in canine Leishmania prevention. Trends Parasitol (2013) 0.75

Jaw Claudication and Temporal Artery Abnormalities in Giant Cell Arteritis: Take Advantage of Clinical Clues: Response. J Neuroophthalmol (2017) 0.75

Ultrastructural and fluorochromatic changes of Anaplasma marginale exposed to oxytetracycline, imidocarb and enrofloxacin in short-term erythrocyte cultures. Vet Microbiol (2008) 0.75