Published in Ann Hematol on October 24, 2013
Laminin-rich blood vessels display activated growth factor signaling and act as the proliferation centers in Dupuytren's contracture. Arthritis Res Ther (2015) 1.41
CTGF increases matrix metalloproteinases expression and subsequently promotes tumor metastasis in human osteosarcoma through down-regulating miR-519d. Oncotarget (2014) 1.23
Revisiting the matricellular concept. Matrix Biol (2014) 1.14
Murine models of acute leukemia: important tools in current pediatric leukemia research. Front Oncol (2014) 0.84
The role of CCN family genes in haematological malignancies. J Cell Commun Signal (2015) 0.81
Tungsten-induced carcinogenesis in human bronchial epithelial cells. Toxicol Appl Pharmacol (2015) 0.79
Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors. Stem Cell Reports (2014) 0.76
High expression of connective tissue growth factor accelerates dissemination of leukaemia. Oncogene (2016) 0.76
The role of the CCN family of proteins in blood cancers. J Cell Commun Signal (2016) 0.75
TNFAIP8 interacts with LATS1 and promotes aggressiveness through regulation of Hippo pathway in hepatocellular carcinoma. Oncotarget (2017) 0.75
Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy. J Diabetes Res (2015) 0.75
AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth. JCI Insight (2017) 0.75
A multigenic program mediating breast cancer metastasis to bone. Cancer Cell (2003) 16.86
All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci (2006) 5.18
CCN proteins: multifunctional signalling regulators. Lancet (2004) 4.88
Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies. Blood (2004) 3.13
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res (2011) 2.21
Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development (2002) 2.16
Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Cancer Res (2006) 1.97
Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas. Clin Cancer Res (2004) 1.85
Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer. PLoS One (2007) 1.79
Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer. Mol Cancer Ther (2006) 1.71
Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. Leukemia (2008) 1.67
The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth. Cancer Res (2009) 1.64
miRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia. Braz J Med Biol Res (2007) 1.59
Connective tissue growth factor (CTGF) expression and outcome in adult patients with acute lymphoblastic leukemia. Blood (2007) 1.46
Desmoplastic reaction influences pancreatic cancer growth behavior. World J Surg (2004) 1.39
CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway. J Cell Sci (2007) 1.33
Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria. Clin J Am Soc Nephrol (2010) 1.30
Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis. Mol Endocrinol (2009) 1.24
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. PLoS One (2011) 1.23
The CCN family proteins in carcinogenesis. Exp Oncol (2010) 1.21
Expression of connective tissue growth factor in cartilaginous tumors. Cancer (2000) 1.19
Connective tissue growth factor gene expression alters tumor progression in esophageal cancer. World J Surg (2002) 1.15
Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts. PLoS One (2012) 1.14
A stromal cell-derived membrane protein that supports hematopoietic stem cells. Nat Immunol (2003) 1.13
AlphaIIb integrin expression during development of the murine hemopoietic system. Dev Biol (2002) 1.13
Hypoxia induces expression of connective tissue growth factor in scleroderma skin fibroblasts. Clin Exp Immunol (2006) 1.12
Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1. Cancer Res (2009) 1.09
Roles for CCN2 in normal physiological processes. Cell Mol Life Sci (2011) 1.06
Interactions between acute lymphoblastic leukemia and bone marrow stromal cells influence response to therapy. Leuk Res (2011) 1.05
Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3'-untranslated region interacting with a cellular protein in human chondrosarcoma cells. Oncogene (2006) 1.05
Connective tissue growth factor associated with oncogenic activities and drug resistance in glioblastoma multiforme. Int J Cancer (2010) 1.04
Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates. Blood (2001) 1.00
The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes. J Biol Chem (2011) 0.98
High expression of connective tissue growth factor in pre-B acute lymphoblastic leukaemia. Br J Haematol (2007) 0.95
Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27(Kip-1). FASEB J (2006) 0.94
CTGF (IGFBP-rP2) is specifically expressed in malignant lymphoblasts of patients with acute lymphoblastic leukaemia (ALL). Br J Cancer (2000) 0.92