Published in Epigenetics on October 29, 2013
HPV-positive oropharyngeal squamous cell carcinoma is associated with TIMP3 and CADM1 promoter hypermethylation. Cancer Med (2014) 0.87
NDN and CD1A are novel prognostic methylation markers in patients with head and neck squamous carcinomas. BMC Cancer (2015) 0.86
Epigenetic changes in the CDKN2A locus are associated with differential expression of P16INK4A and P14ARF in HPV-positive oropharyngeal squamous cell carcinoma. Cancer Med (2015) 0.86
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Gene promoter methylation signature predicts survival of head and neck squamous cell carcinoma patients. Epigenetics (2016) 0.75
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Viral oncoproteins target the DNA methyltransferases. Oncogene (2006) 1.59
Epigenetic inactivation of the SFRP genes is associated with drinking, smoking and HPV in head and neck squamous cell carcinoma. Int J Cancer (2006) 1.53
Emerging roles for retinoids in regeneration and differentiation in normal and disease states. Biochim Biophys Acta (2011) 1.41
Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers. Cancer Causes Control (2010) 1.30
Genome-wide methylation and expression differences in HPV(+) and HPV(-) squamous cell carcinoma cell lines are consistent with divergent mechanisms of carcinogenesis. Epigenetics (2011) 1.29
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Gene expression profiles in HPV-infected head and neck cancer. J Pathol (2007) 1.27
Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability. PLoS One (2009) 1.27
Line region hypomethylation is associated with lifestyle and differs by human papillomavirus status in head and neck squamous cell carcinomas. Cancer Epidemiol Biomarkers Prev (2008) 1.25
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. Genome Med (2013) 1.24
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma. Genome Med (2013) 1.23
p16(INK4A) genetic and epigenetic profiles differ in relation to age and site in head and neck squamous cell carcinomas. Hum Pathol (2008) 1.22
Global hypomethylation identifies Loci targeted for hypermethylation in head and neck cancer. Clin Cancer Res (2011) 1.15
DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements. J Nutr (2002) 1.14
Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts. PLoS One (2011) 1.12
Genome-wide hypomethylation in cancer may be a passive consequence of transformation. Biochim Biophys Acta (2010) 1.08
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Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival. Clin Cancer Res (2012) 1.05
HPV-16 E6 upregulation of DNMT1 through repression of tumor suppressor p53. Oncol Rep (2010) 1.05
HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. J Clin Invest (2013) 1.01
Oncogenic human papillomavirus imposes an instructive pattern of DNA methylation changes which parallel the natural history of cervical HPV infection in young women. Carcinogenesis (2012) 1.01
Epigenetic inactivation of RASSF1A in head and neck cancer. Clin Cancer Res (2003) 1.00
Promoter methylation of cyclin A1 is associated with human papillomavirus 16 induced head and neck squamous cell carcinoma independently of p53 mutation. Mol Carcinog (2011) 1.00
HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18, EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas. Genes Chromosomes Cancer (2010) 0.98
Hypermethylation of E-cadherin is an independent predictor of improved survival in head and neck squamous cell carcinoma. Cancer (2008) 0.97
The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein. Oncogene (2002) 0.95
Role of DNA methylation in head and neck cancer. Clin Epigenetics (2011) 0.94
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Human papillomavirus-associated head and neck squamous cell carcinoma survival: a comparison by tumor site and initial treatment. Head Neck Pathol (2013) 0.93
Prevalence and clinical features of human papillomavirus in head and neck squamous cell carcinoma in Okinawa, southern Japan. Eur Arch Otorhinolaryngol (2011) 0.89
Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation. BMC Cancer (2009) 0.89
Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma. Cell Oncol (Dordr) (2013) 0.89
Relation between human papillomavirus positivity and p16 expression in head and neck carcinomas--a tissue microarray study. Anticancer Res (2007) 0.86
Comprehensive analysis of DNA methylation in head and neck squamous cell carcinoma indicates differences by survival and clinicopathologic characteristics. PLoS One (2013) 0.86
Promoter hypermethylation in primary squamous cell carcinoma of the oral cavity and oropharynx: a study of a Brazilian cohort. Mol Biol Rep (2012) 0.85
Cyclin A1 shows age-related expression in benign tonsils, HPV16-dependent overexpression in HNSCC and predicts lower recurrence rate in HNSCC independently of HPV16. BMC Cancer (2012) 0.83