Published in J Mol Cell Cardiol on December 07, 2013
Hypoxia preconditioned mesenchymal stem cells prevent cardiac fibroblast activation and collagen production via leptin. PLoS One (2014) 1.51
The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis. Circ Res (2016) 1.27
Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities. Transl Res (2014) 0.94
Cutting edge: IL-1α is a crucial danger signal triggering acute myocardial inflammation during myocardial infarction. J Immunol (2014) 0.93
Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function. Am J Physiol Heart Circ Physiol (2014) 0.91
Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest (2016) 0.89
Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges. Transl Res (2015) 0.87
Antifibrotic therapies to control cardiac fibrosis. Biomater Res (2016) 0.86
Role of inflammatory cells in fibroblast activation. J Mol Cell Cardiol (2015) 0.84
Translational horizons in the tumor microenvironment: harnessing breakthroughs and targeting cures. Med Res Rev (2015) 0.83
Sodium hydrosulfide prevents myocardial dysfunction through modulation of extracellular matrix accumulation and vascular density. Int J Mol Sci (2014) 0.82
Three-dimensional histology: tools and application to quantitative assessment of cell-type distribution in rabbit heart. Europace (2014) 0.81
Integrins and integrin-related proteins in cardiac fibrosis. J Mol Cell Cardiol (2015) 0.80
Priming cancer cells for drug resistance: role of the fibroblast niche. Front Biol (Beijing) (2014) 0.80
Cardiac fibroblasts in pressure overload hypertrophy: the enemy within? J Clin Invest (2014) 0.80
Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities. J Mol Cell Cardiol (2015) 0.80
Computational modeling of cardiac fibroblasts and fibrosis. J Mol Cell Cardiol (2015) 0.80
Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration. Cell Tissue Res (2016) 0.79
Influence of aging on the quantity and quality of human cardiac stem cells. Sci Rep (2016) 0.79
Analyzing Remodeling of Cardiac Tissue: A Comprehensive Approach Based on Confocal Microscopy and 3D Reconstructions. Ann Biomed Eng (2015) 0.79
Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium. J Mol Endocrinol (2016) 0.78
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction. PLoS One (2014) 0.78
The circular relationship between matrix metalloproteinase-9 and inflammation following myocardial infarction. IUBMB Life (2015) 0.78
The role of Interleukin Receptor Associated Kinase (IRAK)-M in regulation of myofibroblast phenotype in vitro, and in an experimental model of non-reperfused myocardial infarction. J Mol Cell Cardiol (2015) 0.78
Human cardiac fibroblasts adaptive responses to controlled combined mechanical strain and oxygen changes in vitro. Elife (2017) 0.77
A state of reversible compensated ventricular dysfunction precedes pathological remodelling in response to cardiomyocyte-specific activity of angiotensin II type-1 receptor in mice. Dis Model Mech (2015) 0.77
UM206, a selective Frizzled antagonist, attenuates adverse remodeling after myocardial infarction in swine. Lab Invest (2015) 0.77
Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration. Cell Signal (2014) 0.77
Crosstalk between the heart and peripheral organs in heart failure. Exp Mol Med (2016) 0.77
TGF-β Negatively Regulates CXCL1 Chemokine Expression in Mammary Fibroblasts through Enhancement of Smad2/3 and Suppression of HGF/c-Met Signaling Mechanisms. PLoS One (2015) 0.77
Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction. PLoS One (2014) 0.77
Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. EMBO Mol Med (2016) 0.77
The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart. J Clin Med (2017) 0.77
Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novel MDSC subset. Oncoimmunology (2015) 0.76
Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts. Discoveries (Craiova) (2015) 0.76
Epicardium-Derived Heart Repair. J Dev Biol (2014) 0.76
Fractalkine neutralization improves cardiac function after myocardial infarction. Exp Physiol (2015) 0.76
Redefining the identity of cardiac fibroblasts. Nat Rev Cardiol (2017) 0.75
The role of air pollution in myocardial remodeling. PLoS One (2017) 0.75
Macrophage-Derived mir-155-Containing Exosomes Suppress Fibroblast Proliferation and Promote Fibroblast Inflammation during Cardiac Injury. Mol Ther (2017) 0.75
Astragaloside IV enhances cardioprotection of remote ischemic conditioning after acute myocardial infarction in rats. Am J Transl Res (2016) 0.75
Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proc Natl Acad Sci U S A (2017) 0.75
The Functional Pluralism of Fibroblasts in the Infarcted Myocardium. Circ Res (2016) 0.75
The role of transforming growth factor (TGF)-β in the infarcted myocardium. J Thorac Dis (2017) 0.75
A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction. Sci Rep (2017) 0.75
Cardiac Fibroblast Activation Post-Myocardial Infarction: Current Knowledge Gaps. Trends Pharmacol Sci (2017) 0.75
Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research. Circ Res (2016) 0.75
Fibroblast-Extracellular Matrix Interactions in Tissue Fibrosis. Curr Pathobiol Rep (2016) 0.75
Nod-like receptor protein 3 inflammasome activation by Escherichia coli RNA induces transforming growth factor beta 1 secretion in hepatic stellate cells. Bosn J Basic Med Sci (2016) 0.75
Disruption of calpain reduces lipotoxicity-induced cardiac injury by preventing endoplasmic reticulum stress. Biochim Biophys Acta (2016) 0.75
The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling. Biochim Biophys Acta (2016) 0.75
Myofibroblast secretome and its auto-/paracrine signaling. Expert Rev Cardiovasc Ther (2016) 0.75
Nuquantus: Machine learning software for the characterization and quantification of cell nuclei in complex immunofluorescent tissue images. Sci Rep (2016) 0.75
Role of the immune system in cardiac tissue damage and repair following myocardial infarction. Inflamm Res (2017) 0.75
Protective effect of kaempferol on LPS plus ATP-induced inflammatory response in cardiac fibroblasts. Inflammation (2015) 0.75
Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice. Nat Commun (2017) 0.75
Circadian MicroRNAs in Cardioprotection. Curr Pharm Des (2017) 0.75
IL-1β Inhibition in Cardiovascular Complications Associated to Diabetes Mellitus. Front Pharmacol (2017) 0.75
11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI. J Endocrinol (2017) 0.75
T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway. Naunyn Schmiedebergs Arch Pharmacol (2017) 0.75
IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice. Sci Rep (2017) 0.75
Transforming growth factor β and its role in heart disease. Exp Ther Med (2017) 0.75
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (2004) 10.23
Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation (1990) 9.74
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med (2007) 9.51
The myofibroblast: one function, multiple origins. Am J Pathol (2007) 8.64
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol (2009) 7.34
Formation and function of the myofibroblast during tissue repair. J Invest Dermatol (2007) 6.11
Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res (2005) 4.79
Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res (2007) 4.53
The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res (2006) 4.38
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21
Cardiac fibroblast: the renaissance cell. Circ Res (2009) 4.01
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovasc Res (2013) 3.92
The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol (1998) 3.65
Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease. Circulation (2000) 3.22
Regulation of the inflammatory response in cardiac repair. Circ Res (2012) 3.21
Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation (2007) 3.07
Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol (2007) 2.97
Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation (2011) 2.94
Fibroblast network in rabbit sinoatrial node: structural and functional identification of homogeneous and heterogeneous cell coupling. Circ Res (2004) 2.90
Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice. Proc Natl Acad Sci U S A (2006) 2.85
Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. Am J Pathol (2004) 2.61
The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state? J Clin Invest (2001) 2.55
The myofibroblast: paradigm for a mechanically active cell. J Biomech (2009) 2.53
Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol (1997) 2.47
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload. J Clin Invest (2009) 2.46
Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol (1995) 2.46
Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol (1996) 2.44
Transforming growth factor (TGF)-β signaling in cardiac remodeling. J Mol Cell Cardiol (2010) 2.35
Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol (2001) 2.28
Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol (2003) 2.22
Infarct scar: a dynamic tissue. Cardiovasc Res (2000) 2.21
Novel lipid mediators and resolution mechanisms in acute inflammation: to resolve or not? Am J Pathol (2010) 2.16
Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation (2007) 2.14
Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol (1994) 2.12
Study of non-muscle cells of the adult mammalian heart: a fine structural analysis and distribution. Cytobios (1980) 2.09
Regulation of collagen degradation in the rat myocardium after infarction. J Mol Cell Cardiol (1995) 2.07
Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway. J Cell Sci (2007) 2.03
Matricellular proteins in cardiac adaptation and disease. Physiol Rev (2012) 2.01
Bone marrow-derived cells contribute to infarct remodelling. Cardiovasc Res (2006) 2.00
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res (2010) 2.00
Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol (2008) 1.97
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. Circ Res (2010) 1.94
Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol (2008) 1.90
Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion. Circulation (1998) 1.88
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol (2010) 1.82
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development (2012) 1.81
Chemokines in ischemia and reperfusion. Thromb Haemost (2007) 1.80
Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction. Circ Res (1998) 1.78
Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb). Cardiovasc Res (2000) 1.73
Development and proliferative capacity of cardiac muscle cells. Circ Res (1974) 1.71
Cytokine mRNA expression in postischemic/reperfused myocardium. Am J Pathol (1995) 1.71
The mechanistic basis of infarct healing. Antioxid Redox Signal (2006) 1.69
CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. Am J Pathol (2010) 1.69
The alpha-smooth muscle actin-positive cells in healing human myocardial scars. Am J Pathol (1994) 1.68
Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction. Cardiovasc Res (2004) 1.57
Transforming growth Factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinase-dependent pathway. Am J Respir Crit Care Med (2001) 1.52
The role of platelet-derived growth factor signaling in healing myocardial infarcts. J Am Coll Cardiol (2006) 1.52
Biological activities of fibroblast growth factor-2 in the adult myocardium. Cardiovasc Res (2003) 1.46
Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis. Am J Physiol Heart Circ Physiol (2013) 1.46
Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol (2008) 1.45
The role of IL-1 in the pathogenesis of heart disease. Arch Immunol Ther Exp (Warsz) (2009) 1.45
Fibroblast growth factor-2 regulates myocardial infarct repair: effects on cell proliferation, scar contraction, and ventricular function. Am J Pathol (2007) 1.43
Enhanced fibroblast-myocyte interactions in response to cardiac injury. Circ Res (2010) 1.42
Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation (2009) 1.39
Stem cell factor induction is associated with mast cell accumulation after canine myocardial ischemia and reperfusion. Circulation (1998) 1.39
Altered fibroblast function following myocardial infarction. J Mol Cell Cardiol (2005) 1.37
Arrhythmogenic implications of fibroblast-myocyte interactions. Circ Arrhythm Electrophysiol (2012) 1.32
Type VI collagen induces cardiac myofibroblast differentiation: implications for postinfarction remodeling. Am J Physiol Heart Circ Physiol (2005) 1.31
Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res (2009) 1.28
Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction. Circ Res (2011) 1.28
Regulation of matrix metalloproteinases by cytokines and reactive oxygen/nitrogen species in the myocardium. Heart Fail Rev (2004) 1.22
Smooth muscle alpha-actin expression and myofibroblast differentiation by TGFbeta are dependent upon MK2. J Cell Biochem (2007) 1.20
Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest (1995) 1.18
Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts. Cardiovasc Res (1995) 1.16
Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fibroblasts. J Biol Chem (2006) 1.15
IL-1 induces proinflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium. J Immunol (2013) 1.14
Cytokines and the microcirculation in ischemia and reperfusion. J Mol Cell Cardiol (1998) 1.14
Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction. Circ Res (2011) 1.12
Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis. Circ Res (2002) 1.12
The VEGF angiogenic switch of fibroblasts is regulated by MMP-7 from cancer cells. Oncogene (2007) 1.11
Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype. J Biol Chem (2011) 1.10
Targeting inflammatory pathways in myocardial infarction. Eur J Clin Invest (2013) 1.10
IL-1beta stimulates rat cardiac fibroblast migration via MAP kinase pathways. Am J Physiol Heart Circ Physiol (2006) 1.07
Systematic characterization of myocardial inflammation, repair, and remodeling in a mouse model of reperfused myocardial infarction. J Histochem Cytochem (2013) 1.06
Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis. FASEB J (2008) 1.05
Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts. Arterioscler Thromb Vasc Biol (2012) 1.02
Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts. Am J Physiol Heart Circ Physiol (2009) 1.00
Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res (2006) 1.00
Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens (2006) 0.99
Intracardiac fibroblasts, but not bone marrow derived cells, are the origin of myofibroblasts in myocardial infarct repair. Cardiovasc Pathol (2005) 0.98
ATP released from cardiac fibroblasts via connexin hemichannels activates profibrotic P2Y2 receptors. FASEB J (2012) 0.98
Contractile cells in rat myocardial scar tissue. Lab Invest (1991) 0.98
Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction. Cardiovasc Res (2002) 0.96
Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration. Dev Biol (2012) 0.96
Biomarkers: hopes and challenges in the path from discovery to clinical practice. Transl Res (2012) 0.95
Abolishing myofibroblast arrhythmogeneicity by pharmacological ablation of α-smooth muscle actin containing stress fibers. Circ Res (2011) 0.94
BAMBI (BMP and activin membrane-bound inhibitor) protects the murine heart from pressure-overload biomechanical stress by restraining TGF-β signaling. Biochim Biophys Acta (2012) 0.93
Oncostatin M differentially regulates CXC chemokines in mouse cardiac fibroblasts. Am J Physiol Cell Physiol (2006) 0.91
Vascular mural cells in healing canine myocardial infarcts. J Histochem Cytochem (2004) 0.89
Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities. J Mol Cell Cardiol (2015) 0.80