Next-generation sequencing and real-time quantitative PCR for minimal residual disease detection in B-cell disorders.

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Published in Leukemia on December 17, 2013

Authors

M Ladetto1, M Brüggemann2, L Monitillo1, S Ferrero1, F Pepin3, D Drandi1, D Barbero1, A Palumbo1, R Passera4, M Boccadoro1, M Ritgen2, N Gökbuget5, J Zheng3, V Carlton3, H Trautmann2, M Faham3, C Pott2

Author Affiliations

1: Division of Hematology, A.O. Azienda Ospedaliera Città della Salute e della Scienza di Torino, University of Torino, Torino, Italy.
2: Second Medical Department, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
3: Sequenta Inc, San Francisco, CA, USA.
4: Division of Nuclear Medicine, Statistical Consultant, University of Torino, Torino, Italy.
5: Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital, Frankfurt, Germany.

Associated clinical trials:

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) | NCT00198991

Induction Chemotherapy (R-CHOP Vs. R-FC) Followed by Interferon Maintenance Versus Rituximab Maintenance in MCL (MCLelderly) | NCT00209209

Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL | NCT00209222

Efficacy and Safety of R-HAD Alone or in Combination With Bortezomib in Patients With Relapsed or Refractory MCL ((R-HAD)) | NCT01449344

Evaluation of Maintenance With Bortezomib Plus Daratumumab (V-Dara) After Induction With Bortezomib, Melphalan, Prednisone Plus Daratumumab (VMP-Dara) in Newly Diagnosed Multiple Myeloma (MM) Patients Non-eligible for autoSCT | NCT05218603

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