Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 3912898)

Published in Invest Ophthalmol Vis Sci on February 03, 2014

Authors

Oleg Alekseev1, Kelly Donovan, Jane Azizkhan-Clifford

Author Affiliations

1: Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania.

Articles cited by this

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature (2003) 20.13

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res (2004) 9.70

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell (2004) 5.29

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol (2007) 4.14

CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med (2000) 3.62

Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proc Natl Acad Sci U S A (1989) 3.26

The synthesis and substructure of herpesvirus DNA: the distribution of alkali-labile single strand interruptions in HSV-1 DNA. J Gen Virol (1973) 3.15

Herpes simplex epithelial and stromal keratitis: an epidemiologic update. Surv Ophthalmol (2012) 2.78

DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutat Res (1996) 2.46

Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0. J Virol (1996) 2.25

Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. PLoS Pathog (2009) 2.21

DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proc Natl Acad Sci U S A (2005) 2.20

Using or abusing: viruses and the cellular DNA damage response. Trends Microbiol (2007) 2.12

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat Cell Biol (2002) 2.10

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Mol Cancer Ther (2009) 2.08

Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line. Invest Ophthalmol Vis Sci (2005) 2.02

Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. J Virol (2004) 2.01

The Chk2 protein kinase. DNA Repair (Amst) (2004) 1.85

Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients. J Infect Dis (1998) 1.83

Herpes simplex keratitis. Prog Retin Eye Res (2006) 1.81

Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management. Antimicrob Agents Chemother (2010) 1.73

Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene (2005) 1.57

Herpes keratitis. Prog Retin Eye Res (2012) 1.55

Ocular HSV-1 latency, reactivation and recurrent disease. Semin Ophthalmol (2008) 1.41

PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication. J Cell Sci (2010) 1.35

Intraocular pressure response to topical corticosteroids. Fed Proc (1966) 1.30

Strain specificity of clinical isolates of herpes simplex virus. Arch Ophthalmol (1980) 1.27

Acyclovir-resistant corneal HSV-1 isolates from patients with herpetic keratitis. J Infect Dis (2008) 1.24

Phosphorylation of Sp1 in response to DNA damage by ataxia telangiectasia-mutated kinase. Mol Cancer Res (2007) 1.20

Incidence, recurrence, and outcomes of herpes simplex virus eye disease in Olmsted County, Minnesota, 1976-2007: the effect of oral antiviral prophylaxis. Arch Ophthalmol (2010) 1.18

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev (2010) 1.15

Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth. Virology (2008) 1.11

Multiple receptor interactions trigger release of membrane and intracellular calcium stores critical for herpes simplex virus entry. Mol Biol Cell (2007) 1.10

The ATM signaling network in development and disease. Front Genet (2013) 1.09

Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection. Virol J (2004) 1.08

DNA damage response. Cold Spring Harb Perspect Biol (2011) 1.03

Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer. Mol Cancer Ther (2013) 1.02

Herpes virus genome, the pressure is on. J Am Chem Soc (2013) 1.01

Aciclovir-resistant herpes keratitis. Clin Experiment Ophthalmol (2010) 1.00

Ex vivo organotypic corneal model of acute epithelial herpes simplex virus type I infection. J Vis Exp (2012) 0.97

Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infection. J Virol (2002) 0.96

4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells. Cell Immunol (2006) 0.95

Deciphering novel host-herpesvirus interactions by virion proteomics. Front Microbiol (2012) 0.92

Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein. J Virol (2007) 0.90

Effect of EGF-induced HDAC6 activation on corneal epithelial wound healing. Invest Ophthalmol Vis Sci (2010) 0.89

Surveillance of herpes simplex virus resistance to antivirals: a 4-year survey. Antiviral Res (2013) 0.89

A retrospective, case-control study of acyclovir resistance in herpes simplex virus. Clin Infect Dis (2005) 0.88

A cationic peptide, TAT-Cd°, inhibits herpes simplex virus type 1 ocular infection in vivo. Invest Ophthalmol Vis Sci (2013) 0.86

TFIIB dephosphorylation links transcription inhibition with the p53-dependent DNA damage response. Proc Natl Acad Sci U S A (2012) 0.85

Mediators and mechanisms of herpes simplex virus entry into ocular cells. Curr Eye Res (2010) 0.84

Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling. PLoS Pathog (2013) 0.82

Resistant herpes simplex keratitis. Clin Experiment Ophthalmol (2010) 0.82

Phenotypic and genotypic characterization of induced acyclovir-resistant clinical isolates of herpes simplex virus type 1. Antiviral Res (2013) 0.82

Squamous cell carcinoma of the cornea. Yonsei Med J (2001) 0.81

Ocular manifestations of ataxia-telangiectasia. Am J Ophthalmol (2002) 0.79

Ocular findings in Norwegian patients with ataxia-telangiectasia: a 5 year prospective cohort study. Acta Ophthalmol Scand (2007) 0.77

DANGERS OF STEROIDS IN OPHTHALMOLOGY WITH REPORT OF A CASE OF MYCOTIC PERFORATING CORNEAL ULCER. J Med Assoc State Ala (1964) 0.77

Articles by these authors

Effects of non-thermal plasma on mammalian cells. PLoS One (2011) 3.02

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proc Natl Acad Sci U S A (2003) 2.21

Retracted Non-thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species. Ann Biomed Eng (2010) 1.54

Sp1 and the 'hallmarks of cancer'. FEBS J (2015) 1.38

Phosphorylation of Sp1 in response to DNA damage by ataxia telangiectasia-mutated kinase. Mol Cancer Res (2007) 1.20

Dual regulation of the anaphase promoting complex in human cells by cyclin A-Cdk2 and cyclin A-Cdk1 complexes. Cell Cycle (2006) 1.05

SUMO-1 modification of human cytomegalovirus IE1/IE72. J Virol (2002) 1.03

The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication. J Virol (2005) 0.99

In situ intracellular spectroscopy with surface enhanced Raman spectroscopy (SERS)-enabled nanopipettes. ACS Nano (2009) 0.97

Ex vivo organotypic corneal model of acute epithelial herpes simplex virus type I infection. J Vis Exp (2012) 0.97

Sp1 facilitates DNA double-strand break repair through a nontranscriptional mechanism. Mol Cell Biol (2012) 0.83

The transcription factor SP1 regulates centriole function and chromosomal stability through a functional interaction with the mammalian target of rapamycin/raptor complex. Genes Chromosomes Cancer (2010) 0.81

Activation of checkpoint kinase 2 is critical for herpes simplex virus type 1 replication in corneal epithelium. Ophthalmic Res (2014) 0.76

Interplay between the cell cycle and double-strand break response in mammalian cells. Methods Mol Biol (2014) 0.75