Published in Transplant Proc on October 01, 1987
Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction. Surgery (1988) 5.03
Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications. Transplant Proc (1990) 4.90
Augmentation of rat liver regeneration by FK 506 compared with cyclosporin. Lancet (1989) 2.01
FK 506 as a growth control factor. Transplant Proc (1990) 1.36
Pharmacokinetics of FK506 in liver transplant recipients after continuous intravenous infusion. J Clin Pharmacol (1993) 1.23
Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. PLoS One (2008) 1.12
Acidic calcium stores of Saccharomyces cerevisiae. Cell Calcium (2011) 1.09
FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats. Hepatology (1991) 1.05
Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata. G3 (Bethesda) (2012) 1.02
FK 506 dosage in human organ transplantation. Transplant Proc (1990) 0.99
Calcineurin inactivation leads to decreased responsiveness to LPS in macrophages and dendritic cells and protects against LPS-induced toxicity in vivo. Innate Immun (2009) 0.87
A comprehensive review of immunosuppression used for liver transplantation. J Transplant (2009) 0.86
FK 506 and autoimmune disease: perspective and prospects. Autoimmunity (1992) 0.85
FK506 in solid organ transplantation. Ther Drug Monit (1995) 0.85
Principles of microbial alchemy: insights from the Streptomyces coelicolor genome sequence. Genome Biol (2002) 0.80
Comparison of short-term immunosuppressive therapy with cyclosporine and FK 506 in small-bowel transplantation. Transplant Proc (1990) 0.79
The effect of tacrolimus (FK-506) on Japanese patients with refractory Crohn's disease. J Gastroenterol (2008) 0.78
New immunosuppressive drugs and lung transplantation: last or least? Thorax (1999) 0.77
Use of FK506 and bone marrow mesenchymal stem cells for rat hind limb allografts. Neural Regen Res (2012) 0.76
Lipid parameters, doses and blood levels of calcineurin inhibitors in renal transplant patients. Indian J Clin Biochem (2012) 0.75
Evolving concepts in the selection of immunosuppression regimen for liver transplant recipients. Hepat Med (2011) 0.75
Current status of vascularized composite tissue allotransplantation. Burns Trauma (2014) 0.75
Tacrolimus Pharmacokinetic and Pharmacogenomic Differences between Adults and Pediatric Solid Organ Transplant Recipients. Pharmaceutics (2010) 0.75
The Natural Course of Atopic Dermatitis and the Association with Asthma. Inflammation (2017) 0.75
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot (Tokyo) (1987) 7.07
FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) (1987) 4.54
A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion. Cell (1999) 4.25
Cloning of a Streptococcus mutans glucosyltransferase gene coding for insoluble glucan synthesis. Infect Immun (1986) 4.08
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Mol Biol Cell (1999) 3.27
Electric-field-induced superconductivity in an insulator. Nat Mater (2008) 3.17
Epidemiological studies on patients with a persistent vegetative state. J Neurol Neurosurg Psychiatry (1977) 2.81
The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria. Antimicrob Agents Chemother (1998) 2.73
A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo. Oncogene (2006) 2.37
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity. J Antibiot (Tokyo) (1994) 2.28
Conversion of penicillin N to cephalosporin(s) by cell-free extracts of Cephalosporium acremonium. Biochem Biophys Res Commun (1976) 2.27
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res (2000) 2.14
Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts. J Bacteriol (1987) 2.08
Mechanism of cell detachment from temperature-modulated, hydrophilic-hydrophobic polymer surfaces. Biomaterials (1995) 2.04
Calcium signalling in the guidance of nerve growth by netrin-1. Nature (2000) 1.96
Dental pulp cells for induced pluripotent stem cell banking. J Dent Res (2010) 1.92
Discovery of superconductivity in KTaO₃ by electrostatic carrier doping. Nat Nanotechnol (2011) 1.89
New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo) (1996) 1.87
Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration. Cell (1996) 1.85
Sodic soils reclaimed with by-product from flue gas desulfurization: corn production and soil quality. Environ Pollut (2001) 1.76
Laparoscopic omental patch repair for perforated peptic ulcer. Ann Surg (1995) 1.74
A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis. Genome Res (1999) 1.65
Development of a host-vector system in a Rhodococcus strain and its use for expression of the cloned nitrile hydratase gene cluster. J Gen Microbiol (1992) 1.60
Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2). Gene (1990) 1.57
Increased circulating vascular endothelial growth factor is correlated with disease activity in polyarticular juvenile rheumatoid arthritis. J Rheumatol (1999) 1.57
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc Natl Acad Sci U S A (1997) 1.56
New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo) (1996) 1.56
Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes. J Immunol (2000) 1.54
Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex. J Neurosci (1997) 1.52
Cloning and sequencing of the gene cluster encoding two subunits of membrane-bound alcohol dehydrogenase from Acetobacter polyoxogenes. Biochim Biophys Acta (1991) 1.51
Nucleotide sequence and transcriptional analysis of the Streptomyces griseus gene (afsA) responsible for A-factor biosynthesis. J Bacteriol (1989) 1.50
Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product. Eur J Biochem (1993) 1.50
Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells. Biosci Biotechnol Biochem (1994) 1.49
Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer. Eur J Cancer (1999) 1.46
The crystal structure of coxsackievirus A9: new insights into the uncoating mechanisms of enteroviruses. Structure (1999) 1.43
Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma. J Clin Invest (1996) 1.43
Nucleotide sequence of the malate dehydrogenase gene of Thermus flavus and its mutation directing an increase in enzyme activity. J Biol Chem (1986) 1.42
Optimal level of pressure support ventilation for recovery from diaphragmatic fatigue in rabbits. Crit Care Med (2000) 1.40
Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein. J Biol Chem (2000) 1.39
Effects of pressure-support ventilation on recovery from acute diaphragmatic fatigue in rabbits. Crit Care Med (1998) 1.39
Evidence for an origin of ethyl-nitrosourea-induced rat central nervous system tumors from pluripotent germinal neuroepithelium. Acta Neuropathol (1994) 1.38
Cell-free ring expansion of penicillin N to deacetoxycephalosporin C by Cephalosporium acremonium CW-19 and its mutants. Proc Natl Acad Sci U S A (1978) 1.37
Toxicologic evaluation of FK 506. Transplant Proc (1990) 1.36
The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic role. Mol Med (1996) 1.35
A physical map with yeast artificial chromosome (YAC) clones covering 63% of the 12 rice chromosomes. Genome (2001) 1.35
Nocardicin A, a new monocyclic beta-lactam antibiotic. I. Discovery, isolation and characterization. J Antibiot (Tokyo) (1976) 1.35
Inducement of a heat-shock requirement for germination and production of increased heat resistance in Bacillus fastidiosus spores by manganous ions. J Bacteriol (1973) 1.34
Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells. Oncogene (2006) 1.33
Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability. Oncogene (2006) 1.32
Quantitative lymph imaging for assessment of lymph function using indocyanine green fluorescence lymphography. Eur J Vasc Endovasc Surg (2008) 1.31
Solution structure of the SH3 domain of phospholipase C-gamma. Cell (1993) 1.31
Allergy to insects in Japan. III. High frequency of IgE antibody responses to insects (moth, butterfly, caddis fly, and chironomid) in patients with bronchial asthma and immunochemical quantitation of the insect-related airborne particles smaller than 10 microns in diameter. J Allergy Clin Immunol (1987) 1.29
A novel monoclonal antibody (OPD4) recognizing a helper/inducer T cell subset. Its application to paraffin-embedded tissues. Am J Pathol (1989) 1.28
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli. Eur J Biochem (1989) 1.26
Indocyanine green fluorescence angiography for intraoperative assessment of blood flow: a feasibility study. Eur J Vasc Endovasc Surg (2007) 1.25
Penetration of brain and brain tumor. VII. Tumor-binding sulfhydryl boron compounds. J Med Chem (1967) 1.24
Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry (1993) 1.24
Histone deacetylase as a new target for cancer chemotherapy. Cancer Chemother Pharmacol (2001) 1.24
Comparison of postoperative early active mobilization and immobilization in vivo utilising a four-strand flexor tendon repair. J Hand Surg Br (2001) 1.23
Crystal structure of the fungal peroxidase from Arthromyces ramosus at 1.9 A resolution. Structural comparisons with the lignin and cytochrome c peroxidases. J Mol Biol (1994) 1.22
Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells. Brain Res (1996) 1.22
Plasma brain natriuretic peptide concentrations predict survival after acute myocardial infarction. J Am Coll Cardiol (1996) 1.21
Prolongation of skin allograft survival in rats by a novel immunosuppressive agent, FK506. Transplantation (1988) 1.21
Isolation and characterization of the sucrose 6-phosphate hydrolase gene from Streptococcus mutans. Infect Immun (1986) 1.21
Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells. J Neurochem (2001) 1.20
The role of C-C chemokines and their receptors in osteoarthritis. Arthritis Rheum (2001) 1.20
Studies on thiopeptin antibiotics. I. Characteristics of thiopeptin B. J Antibiot (Tokyo) (1970) 1.20
Studies on new phosphonic acid antibiotics. I. FR-900098, isolation and characterization. J Antibiot (Tokyo) (1980) 1.20
Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif. EMBO J (2001) 1.20
Nerve growth factor-mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic AMP-independent process. FEBS Lett (1978) 1.19
Synchronous growth and sporulation of Bacillus megaterium. J Bacteriol (1967) 1.18
Involvement of the COOH-terminal pro-sequence of Serratia marcescens serine protease in the folding of the mature enzyme. J Biol Chem (1994) 1.18
Studies on pyrrolnitrin, a new antibiotic. I. Isolation and properties of pyrrolnitrin. J Antibiot (Tokyo) (1965) 1.16
Biological characterization and optical imaging of brain-derived neurotrophic factor-green fluorescent protein suggest an activity-dependent local release of brain-derived neurotrophic factor in neurites of cultured hippocampal neurons. J Neurosci Res (2001) 1.16
Aspartate kinase-independent lysine synthesis in an extremely thermophilic bacterium, Thermus thermophilus: lysine is synthesized via alpha-aminoadipic acid not via diaminopimelic acid. J Bacteriol (1999) 1.16
Detection of bcl-2 protein and bcl-2 messenger RNA in normal and neoplastic lymphoid tissues by immunohistochemistry and in situ hybridization. Blood (1992) 1.16
Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes. Proc Natl Acad Sci U S A (2001) 1.15
Immunosuppressive effect of FK506 on collagen-induced arthritis in rats. Clin Immunol Immunopathol (1988) 1.15
Seasonal variation in the human circadian rhythm: dissociation between sleep and temperature rhythm. Am J Physiol (1992) 1.15
Clinical trial: dose-dependent therapeutic efficacy of acotiamide hydrochloride (Z-338) in patients with functional dyspepsia - 100 mg t.i.d. is an optimal dosage. Neurogastroenterol Motil (2010) 1.13
Synovial sarcoma of the hand. Skeletal Radiol (1997) 1.13
Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations. Biochemistry (1992) 1.13