A mechanistic model of drug-induced liver injury AIDS the interpretation of elevated liver transaminase levels in a phase I clinical trial.

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🔗 View Article (PMC 3944113)

Published in CPT Pharmacometrics Syst Pharmacol on February 05, 2014

Authors

B A Howell1, S Q Siler1, L K M Shoda1, Y Yang1, J L Woodhead1, P B Watkins2

Author Affiliations

1: The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes, Research Triangle Park, North Carolina, USA.
2: 1] The Hamner-UNC Institute for Drug Safety Sciences, The Hamner Institutes, Research Triangle Park, North Carolina, USA [2] School of Medicine and School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Associated clinical trials:

Entolimod, an Adjuvant for Vaccine Augmentation | NCT03063736

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