PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer.

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Published in PLoS One on February 27, 2014

Authors

Zhiqiang Guo1, Xin Wang2, Dali Cheng1, Zhijun Xia1, Meng Luan3, Shulan Zhang1

Author Affiliations

1: Department of Gynecology and Obstetrics, Shengjing Hospital, China Medical University, ShenYang, China.
2: Department of Gynecology and Obstetrics, No. 306 Hospital of PLA, Beijing, China.
3: Department of Gynecology and Obstetrics, The First Affiliated Hospital, China Medical University, Shen Yang, China.

Associated clinical trials:

Anti-OX40, Cyclophosphamide (CTX) and Radiation in Patients With Progressive Metastatic Prostate Cancer | NCT01303705

Stereotactic Body Radiation and Monoclonal Antibody to OX40 (MEDI6469) in Breast Cancer Patients With Metastatic Lesions (OX40 Breast) | NCT01862900

Phase 1 Study of Anti-OX40 in Patients With Advanced Cancer | NCT01644968

NCT01642290

Study of Immune Responses in Patients With Metastatic Melanoma | NCT01416844

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