Mutational signatures: the patterns of somatic mutations hidden in cancer genomes.

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Published in Curr Opin Genet Dev on December 29, 2013

Authors

Ludmil B Alexandrov1, Michael R Stratton2

Author Affiliations

1: Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, United Kingdom. Electronic address: la2@sanger.ac.uk.
2: Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, United Kingdom.

Associated clinical trials:

Etiosarc: Environmental Aetiology of Sarcomas From a Multicenter French Population-based Case-control Study Among Adults (ETIOSARC) | NCT03670927

5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer. | NCT04689347

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