Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids.

PubWeight™: 0.84‹?›

🔗 View Article (PMID 24699892)

Published in Eur J Appl Physiol on April 04, 2014

Authors

Peter L McLennan1

Author Affiliations

1: Graduate School of Medicine and Centre for Human Applied Physiology, University of Wollongong, Wollongong, NSW, 2522, Australia, peter_mclennan@uow.edu.au.

Articles cited by this

(truncated to the top 100)

Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J (1996) 16.86

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet (1999) 13.19

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet (2008) 10.02

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet (2007) 9.56

Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet (1989) 9.27

Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. N Engl J Med (1989) 9.08

Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation (2002) 9.02

Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA (2006) 7.73

n-3 fatty acids in patients with multiple cardiovascular risk factors. N Engl J Med (2013) 7.24

Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol (2011) 5.31

The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med (1985) 4.79

Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation (2002) 4.56

N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med (2002) 4.33

Resting heart rate in cardiovascular disease. J Am Coll Cardiol (2007) 4.14

Heart rate and cardiovascular mortality: the Framingham Study. Am Heart J (1987) 4.12

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ Res (2010) 3.99

Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis? Lancet (1978) 3.74

The Omega-3 Index: a new risk factor for death from coronary heart disease? Prev Med (2004) 3.52

Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest. JAMA (1995) 3.48

Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. BMJ (2006) 3.47

Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation (2009) 3.23

Heart rate variability: measurement and clinical utility. Ann Noninvasive Electrocardiol (2005) 3.15

Fish consumption and risk of sudden cardiac death. JAMA (1998) 3.06

n-3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik. Am J Clin Nutr (2001) 3.05

n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr (2003) 2.82

Cardiovascular effects of n-3 fatty acids. N Engl J Med (1988) 2.68

The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N Engl J Med (1993) 2.64

alpha-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans. Prostaglandins Leukot Essent Fatty Acids (2009) 2.62

Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomed Pharmacother (2006) 2.47

Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim Biophys Acta (2000) 2.47

Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod Nutr Dev (2005) 2.28

Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. Circulation (2005) 2.12

Does fish oil lower blood pressure? A meta-analysis of controlled trials. Circulation (1993) 2.09

Prediction of sudden cardiac death after myocardial infarction in the beta-blocking era. J Am Coll Cardiol (2003) 2.06

Omega 3 fatty acids for prevention and treatment of cardiovascular disease. Cochrane Database Syst Rev (2004) 2.05

Dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults. Circulation (2008) 2.02

Do omega-3 polyunsaturated fatty acids reduce risk of sudden cardiac death and ventricular arrhythmias? A meta-analysis of randomized trials. Heart Lung (2013) 1.97

Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ (2010) 1.89

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem (2010) 1.83

Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: correlation with erythrocytes and response to supplementation. Circulation (2004) 1.79

Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids. Lipids (2003) 1.78

Fish intake and risk of incident heart failure. J Am Coll Cardiol (2005) 1.74

Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension (1999) 1.73

External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids. Proc Natl Acad Sci U S A (1994) 1.73

Dietary fish oil prevents ventricular fibrillation following coronary artery occlusion and reperfusion. Am Heart J (1988) 1.71

A quantitative systematic review of normal values for short-term heart rate variability in healthy adults. Pacing Clin Electrophysiol (2010) 1.67

Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs. Circulation (1999) 1.65

Dietary fish oil reduces pacemaker current and heart rate in rabbit. Heart Rhythm (2009) 1.65

A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution. Histochem Cell Biol (2004) 1.62

Prevention of ischemia-induced ventricular fibrillation by omega 3 fatty acids. Proc Natl Acad Sci U S A (1994) 1.62

Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes. Proc Natl Acad Sci U S A (1995) 1.61

Marine n-3 fatty acids, wine intake, and heart rate variability in patients referred for coronary angiography. Circulation (2001) 1.61

Omega-6 and omega-3 fatty acids: partners in prevention. Curr Opin Clin Nutr Metab Care (2010) 1.60

Suppression of voltage-gated L-type Ca2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes. Proc Natl Acad Sci U S A (1997) 1.59

Prognostic value of heart rate variability in chronic congestive heart failure (Veterans Affairs' Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure). Am J Cardiol (2002) 1.59

Fatty acids in cardiovascular health and disease: a comprehensive update. J Clin Lipidol (2012) 1.59

Fish consumption is associated with lower heart rates. Circulation (2003) 1.56

Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids. J Nutr (2009) 1.56

Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res (2007) 1.50

Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci U S A (1992) 1.50

Plasma lipids and lipoproteins in Greenlandic west coast Eskimos. Acta Med Scand (1972) 1.49

Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr (2010) 1.47

Significance of classifying antiarrhythmic actions since the cardiac arrhythmia suppression trial. J Clin Pharmacol (1991) 1.46

Oxidative stress caused by mitochondrial calcium overload. Ann N Y Acad Sci (2010) 1.46

Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men. Circulation (2000) 1.43

Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A (1994) 1.43

Effects of fish-oil supplementation on myocardial fatty acids in humans. Am J Clin Nutr (2007) 1.42

Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function. Circulation (2002) 1.41

The 'Sicilian Gambit'. A new approach to the classification of antiarrhythmic drugs based on their actions on arrhythmogenic mechanisms. The Task Force of the Working Group on Arrhythmias of the European Society of Cardiology. Eur Heart J (1991) 1.39

Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation. Prostaglandins Other Lipid Mediat (2012) 1.38

Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A (1995) 1.37

Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey. Am Heart J (1992) 1.37

Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. Biochim Biophys Acta (2010) 1.36

The cardiovascular protective role of docosahexaenoic acid. Eur J Pharmacol (1996) 1.36

Calcium and cardiac arrhythmias: DADs, EADs, and alternans. Crit Rev Clin Lab Sci (2003) 1.33

Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury. Free Radic Biol Med (2007) 1.31

Fish oil reduces heart rate and oxygen consumption during exercise. J Cardiovasc Pharmacol (2008) 1.30

Prostaglandin I3 is formed in vivo in man after dietary eicosapentaenoic acid. Nature (1984) 1.30

Protective effect of eicosapentaenoic acid on ouabain toxicity in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A (1990) 1.29

Dietary intake of long-chain omega-3 polyunsaturated fatty acids: contribution of meat sources. Nutrition (2005) 1.28

Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J (2011) 1.28

Myocardial membrane fatty acids and the antiarrhythmic actions of dietary fish oil in animal models. Lipids (2001) 1.28

Duration of diastole and its phases as a function of heart rate during supine bicycle exercise. Am J Physiol Heart Circ Physiol (2004) 1.27

Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats. Am J Clin Nutr (1993) 1.26

Position of the academy of nutrition and dietetics: dietary fatty acids for healthy adults. J Acad Nutr Diet (2014) 1.26

Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins. Proc Natl Acad Sci U S A (1996) 1.24

Docosahexaenoic acid affects cell signaling by altering lipid rafts. Reprod Nutr Dev (2005) 1.23

Determinants of erythrocyte omega-3 fatty acid content in response to fish oil supplementation: a dose-response randomized controlled trial. J Am Heart Assoc (2013) 1.23

Effect of fish oil on heart rate variability in survivors of myocardial infarction: a double blind randomised controlled trial. BMJ (1996) 1.22

Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms. J Physiol (2006) 1.22

PUFA and aging modulate cardiac mitochondrial membrane lipid composition and Ca2+ activation of PDH. Am J Physiol (1999) 1.21

Resolvin E1 protects the rat heart against reperfusion injury. Am J Physiol Heart Circ Physiol (2010) 1.20

Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans. Am J Clin Nutr (1998) 1.20

Eicosanoid signalling pathways in the heart. Cardiovasc Res (2008) 1.19

Influence of dietary lipids on arrhythmias and infarction after coronary artery ligation in rats. Can J Physiol Pharmacol (1985) 1.18

Differential effects of various eicosanoids on the production or prevention of arrhythmias in cultured neonatal rat cardiac myocytes. Prostaglandins (1997) 1.17

Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels. J Mol Cell Cardiol (2009) 1.17

Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition. Lipids (2004) 1.16

Cardiovascular disease risk factors and n-3 fatty acid status in the adult population of James Bay Cree. Am J Clin Nutr (2002) 1.16

Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes. Proc Natl Acad Sci U S A (1994) 1.16