An international interpretation study using the ALK IHC antibody D5F3 and a sensitive detection kit demonstrates high concordance between ALK IHC and ALK FISH and between evaluators.

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Published in J Thorac Oncol on May 01, 2014

Authors

Murry W Wynes1, Lynette M Sholl, Manfred Dietel, Ed Schuuring, Ming S Tsao, Yasushi Yatabe, Raymond R Tubbs, Fred R Hirsch

Author Affiliations

1: *Department of Medicine, Division of Medical Oncology, University of Colorado, Aurora, Colorado; †Department of Pathology Brigham and Women's Hospital, Boston, Massachusetts; ‡Institute of Pathology, Charité University Hospital Berlin, Germany; §Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, The Netherlands; ‖Princess Margaret Hospital, University Health Network, University of Toronto, Ontario, Canada; ¶Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Kanokoden, Chikusa-ku, Nagoya, Japan; #Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio; ** Department of Pathology, University of Colorado, Aurora, Colorado; and ††University of Colorado Comprehensive Cancer Center, Aurora, Colorado.

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