Published in Infect Immun on August 01, 1989
Agents that increase the permeability of the outer membrane. Microbiol Rev (1992) 7.52
Host defense peptides in the oral cavity and the lung: similarities and differences. J Dent Res (2008) 1.19
Immunohistochemical localization of defensin in human coronary vessels. Am J Pathol (1997) 1.11
Polymorphic expression of defensins in neutrophils from outbred rats. Infect Immun (1990) 1.08
Characterization of chlamydial genital infection resulting from sexual transmission from male to female guinea pigs and determination of infectious dose. Infect Immun (2003) 0.92
The use of antimicrobial peptides in ophthalmology: an experimental study in corneal preservation and the management of bacterial keratitis. Trans Am Ophthalmol Soc (2002) 0.90
Murine beta-defensin 2 promotes TLR-4/MyD88-mediated and NF-kappaB-dependent atypical death of APCs via activation of TNFR2. J Leukoc Biol (2008) 0.88
Isolation, antimicrobial activities, and primary structures of hamster neutrophil defensins. Infect Immun (1996) 0.83
Modulation of the complement system by human beta-defensin 2. J Burns Wounds (2007) 0.80
Involvement of cysteine residues in the biological activity of the active fragments of guinea pig neutrophil cationic peptides. Infect Immun (1995) 0.75
Tissue sulfhydryl groups. Arch Biochem Biophys (1959) 61.89
Disk electrophoresis of basic proteins and peptides on polyacrylamide gels. Nature (1962) 20.19
A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther (1959) 16.61
Molecular weight analysis of oligopeptides by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate. Anal Biochem (1971) 13.83
Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest (1985) 8.63
Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun (1984) 5.30
Cationic proteins of polymorphonuclear leukocyte lysosomes. II. Composition, properties, and mechanism of antibacterial action. J Bacteriol (1966) 4.81
Primary structures of three human neutrophil defensins. J Clin Invest (1985) 3.70
Cationic proteins of polymorphonuclear leukocyte lysosomes. I. Resolution of antibacterial and enzymatic activities. J Bacteriol (1966) 3.61
Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem (1985) 3.58
Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J Biol Chem (1983) 3.00
Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin. Infect Immun (1987) 2.16
Mediators of inflammation in leukocyte lysosomes. VI. Partial purification and characterization of a mast cell-rupturing component. J Exp Med (1966) 2.15
Modulation of cyclic AMP in purified rat mast cells. I. Responses to pharmacologic, metabolic, and physical stimuli. J Immunol (1975) 2.07
Isolation and characterization of permeability factors from rabbit neutrophils. J Exp Med (1968) 2.00
Procedures for immunochemical study of histamine release from leukocytes with small volume of blood. J Allergy (1970) 1.87
Carboxypeptidase Y in sequence determination of peptides. Methods Enzymol (1977) 1.80
Determination of the amino acid sequence of porcine trypsin by sequenator aalysis. Biochemistry (1973) 1.68
Mechanism of histamine release from mast cells by cationic protein (band 2) from neutrophil lysosomes. J Immunol (1971) 1.24
Mediators of inflammation in leukocyte lysosomes. VII. Observations on mast cell-rupturing agents in different species. Lab Invest (1968) 1.15
Effect of endocellular cryoprotectant upon polymorphonuclear neutrophil function during storage at low temperature. Cryobiology (1979) 0.96
Purification and characterization of a phagocytosis-stimulating factor from phagocytosing polymorphonuclear neutrophils: comparison with granule basic proteins. Infect Immun (1985) 0.84
Possible involvement of aminopeptidase, an ecto-enzyme, in the inactivation of bradykinin by intact neutrophils. Biochim Biophys Acta (1985) 0.80
No direct involvement of plasma membrane divalent cation-activated adenosine triphosphatase in histamine release from rat mast cells. Biochem Biophys Res Commun (1987) 0.78
Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution. Nature (1995) 7.62
CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res (1998) 6.42
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood (2001) 5.17
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Nature (1998) 3.86
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature (1991) 3.48
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood (1999) 3.46
Mini-laparoscopic appendectomy using a needle loop retractor offers optimal cosmetic results. Surg Endosc (2004) 3.38
A high-speed atomic force microscope for studying biological macromolecules. Proc Natl Acad Sci U S A (2001) 2.97
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene. Nat Genet (2001) 2.79
Single molecule imaging of fluorophores and enzymatic reactions achieved by objective-type total internal reflection fluorescence microscopy. Biochem Biophys Res Commun (1997) 2.65
RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli. Proc Natl Acad Sci U S A (1997) 2.51
Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. Circulation (2001) 2.36
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression. Mol Psychiatry (2009) 2.36
Essential role for Gab2 in the allergic response. Nature (2001) 2.32
A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structure. J Exp Med (1993) 2.29
Chemical components in the cell wall of Salmonella typhimurium affecting its virulence and immunogenicity in mice. Nature (1969) 2.22
Down-regulation of CD40 and CD80 on B cells in patients with life-threatening systemic lupus erythematosus after successful treatment with rituximab. Rheumatology (Oxford) (2004) 2.19
Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain (1992) 2.09
The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana. Plant J (2000) 2.09
Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival. J Biol Chem (1993) 2.07
Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study. Ann Rheum Dis (2010) 2.04
Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain. J Neurosci (1987) 1.94
Identification of bipotential progenitor cells in human liver development. Hepatology (1996) 1.84
Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices. Brain Res (1991) 1.81
Endoscopic submucosal dissection: a safe technique for colorectal tumors. Endoscopy (2007) 1.71
Genetic pathways in the evolution of morphologically distinct colorectal neoplasms. Cancer Res (2001) 1.70
Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR. Clin Chem (2001) 1.69
Regulation of sulfur assimilation in higher plants: a sulfate transporter induced in sulfate-starved roots plays a central role in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1997) 1.67
Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system. Dev Dyn (2005) 1.66
Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho). Leukemia (1997) 1.66
Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport. Brain Res (1978) 1.64
Variation of the mexT gene, a regulator of the MexEF-oprN efflux pump expression in wild-type strains of Pseudomonas aeruginosa. FEMS Microbiol Lett (2000) 1.60
Gastrointestinal stromal tumors and KIT-positive mesenchymal cells in the omentum. Pathol Int (2001) 1.59
Intra-arterial infusion of fasudil hydrochloride for treating vasospasm following subarachnoid haemorrhage. Acta Neurochir (Wien) (1999) 1.57
Ischemic stroke and the gene for angiotensin-converting enzyme in Japanese hypertensives. Circulation (1996) 1.57
Simultaneous detection of several Fusarium mycotoxins in cereals, grains, and foodstuffs. J Assoc Off Anal Chem (1981) 1.57
The effect of epidural saline injection on analgesic level during combined spinal and epidural anesthesia assessed clinically and myelographically. Anesth Analg (1997) 1.57
Commonly deleted regions on the long arm of chromosome 21 in differentiated adenocarcinoma of the stomach. Genes Chromosomes Cancer (1997) 1.56
Etiology of cerebral vasospasm in primates. J Neurosurg (1991) 1.53
Fine structure of the sensory epithelium of guinea-pig organ of Corti: subsurface cisternae and lamellar bodies in the outer hair cells. Cell Tissue Res (1983) 1.52
Case report: Occurrence of hepatocellular carcinoma 4.5 years after successful treatment with virus clearance for chronic hepatitis C. J Gastroenterol Hepatol (1999) 1.51
Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism. Eur J Immunol (2001) 1.51
Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters. Proc Natl Acad Sci U S A (2001) 1.50
Spontaneous regression of hepatocellular carcinoma and review of literature. J Gastroenterol Hepatol (2000) 1.50
Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins. J Biol Chem (1993) 1.50
Highly sensitive ELISA for soluble Fas in serum: increased soluble Fas in the elderly. Clin Chem (1996) 1.49
Iron metabolism in the erythrophagocytosing Kupffer cell. Hepatology (1988) 1.49
The fine structural localization of glutamate decarboxylase in synaptic terminals of rodent cerebellum. Brain Res (1974) 1.48
Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana. J Biol Chem (1998) 1.47
Molecular mimicry between GQ1b ganglioside and lipopolysaccharides of Campylobacter jejuni isolated from patients with Fisher's syndrome. Ann Neurol (1994) 1.47
CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins. Cancer Res (1999) 1.46
Hypocalcemic heart failure: a reversible form of heart muscle disease. Clin Cardiol (1998) 1.45
The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction. Mol Cell Biol (1993) 1.45
Microsatellite instability in gallbladder carcinoma: two independent genetic pathways of gallbladder carcinogenesis. J Gastroenterol (2000) 1.44
The NMR-mouse: construction, excitation, and applications. Magn Reson Imaging (1999) 1.44
Significance of fetal fibronectin and cytokine measurement in the cervicovaginal secretions of women at term in predicting term labor and post-term pregnancy. Eur J Obstet Gynecol Reprod Biol (2001) 1.44
Small head circumference at birth in schizophrenia. Schizophr Res (1996) 1.44
Essential hypertension and neurovascular compression at the ventrolateral medulla oblongata: MR evaluation. AJNR Am J Neuroradiol (1995) 1.43
Prevalence of depressive symptoms in a Japanese occupational setting: a preliminary study. Am J Public Health (1989) 1.42
Overexpression of stathmin in oral squamous-cell carcinoma: correlation with tumour progression and poor prognosis. Br J Cancer (2006) 1.42
HbA(1c) variability and the development of microalbuminuria in type 2 diabetes: Tsukuba Kawai Diabetes Registry 2. Diabetologia (2012) 1.41
Differential volumetry of A, B and D cells in the pancreatic islets of diabetic and nondiabetic subjects. Tohoku J Exp Med (1979) 1.41
An outbreak of acute enteritis due to Campylobacter fetus subspecies jejuni at a nursery school of Tokyo. Microbiol Immunol (1980) 1.40
Brugada syndrome associated with an autonomic disorder. Heart (1998) 1.40
The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor. Biochem J (1995) 1.40
Structure and expression analyses of the S-adenosylmethionine synthetase gene family in Arabidopsis thaliana. Gene (1989) 1.39
Alloimmune neonatal neutropenia in monozygous twins. High-dose intravenous gammaglobulin therapy. Acta Paediatr Scand (1991) 1.39
Suprasellar ectopic pituitary adenoma. Acta Neurochir (Wien) (1997) 1.39
Effect of Web-based lifestyle modification on weight control: a meta-analysis. Int J Obes (Lond) (2011) 1.36
Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene. Mol Cell Biol (1994) 1.36
Magnetic stimulation of motor cortex in children: maturity of corticospinal pathway and problem of clinical application. Brain Dev (1997) 1.35
Imaging and nano-manipulation of single biomolecules. Biophys Chem (1997) 1.34
Human microglia convert l-tryptophan into the neurotoxin quinolinic acid. Biochem J (1996) 1.32
Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines. Jpn J Cancer Res (1996) 1.32
Novel mutations and genotype-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD). Hum Mol Genet (1999) 1.31
Clinical and pathologic findings in 52 consecutively autopsied cases with multiple myeloma. Am J Hematol (2001) 1.30
The gamma-subunit rotation and torque generation in F1-ATPase from wild-type or uncoupled mutant Escherichia coli. Proc Natl Acad Sci U S A (1999) 1.29
Organ doses from environmental exposures calculated using voxel phantoms of adults and children. Phys Med Biol (2012) 1.29
Identification of bipotential progenitor cells in human liver regeneration. Lab Invest (1996) 1.26
Molecular biology of the plastidic phosphorylated serine biosynthetic pathway in Arabidopsis thaliana. Amino Acids (2001) 1.26
Characterization of extracellular matrix components in the limbal epithelial stem cell compartment. Exp Eye Res (2007) 1.26
Molecular cloning of two new heat shock genes related to the hsp70 genes in Staphylococcus aureus. J Bacteriol (1994) 1.25
Endodermal sinus tumor of the stomach. Acta Pathol Jpn (1985) 1.25
Idiopathic hypertrophic cranial pachymeningitis: clinicoradiological spectrum and therapeutic options. Neurosurgery (1999) 1.24
Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types. Biochem J (1997) 1.24
beta-Cyanoalanine synthase is a mitochondrial cysteine synthase-like protein in spinach and Arabidopsis. Plant Physiol (2000) 1.23
Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques. FASEB J (1998) 1.23
Conversion of monogalactosyldiacylglycerols to triacylglycerols in ozone-fumigated spinach leaves. Plant Physiol (1990) 1.23
Reversible control of synaptic transmission in a single gene mutant of Drosophila melanogaster. J Cell Biol (1983) 1.23
Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients. J Neuroimmunol (1992) 1.22
Orientation dependence of displacements by a single one-headed myosin relative to the actin filament. Biophys J (1998) 1.22
Airway management for patients with a tracheal bronchus. Br J Anaesth (1996) 1.22
Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid. Biochem J (1992) 1.21
Mutations in c-kit gene exons 9 and 13 in gastrointestinal stromal tumors among Japanese. Jpn J Cancer Res (2001) 1.21
A clinical and pathologic study of a large Japanese family with Machado-Joseph disease tightly linked to the DNA markers on chromosome 14q. Neurology (1994) 1.21
Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase. Antimicrob Agents Chemother (1999) 1.20
T cells from eosinophilic patients produce interleukin-5 with interleukin-2 stimulation. Blood (1989) 1.20
Conversion of l-Sorbosone to l-Ascorbic Acid by a NADP-Dependent Dehydrogenase in Bean and Spinach Leaf. Plant Physiol (1990) 1.19