Published in Crit Care on April 25, 2014
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2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med (2003) 10.39
A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med (2003) 10.13
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A randomized trial of glutamine and antioxidants in critically ill patients. N Engl J Med (2013) 8.94
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Transfusion strategies for patients in pediatric intensive care units. N Engl J Med (2007) 7.21
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High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood (2011) 6.50
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Aspirin in patients undergoing noncardiac surgery. N Engl J Med (2014) 6.10
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Systematic overview of warfarin and its drug and food interactions. Arch Intern Med (2005) 5.86
A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med (2006) 5.74
A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. N Engl J Med (2015) 5.28
Dalteparin versus unfractionated heparin in critically ill patients. N Engl J Med (2011) 4.59
Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA (2012) 4.58
Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 4.41
Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol (2014) 4.39
Toothbrushing for critically ill mechanically ventilated patients: a systematic review and meta-analysis of randomized trials evaluating ventilator-associated pneumonia. Crit Care Med (2013) 4.29
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
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Clinical consequences of red cell storage in the critically ill. Transfusion (2006) 3.57
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A comparison of three methods to estimate baseline creatinine for RIFLE classification. Nephrol Dial Transplant (2010) 3.45
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Acute kidney injury after cardiac surgery: focus on modifiable risk factors. Circulation (2009) 3.10
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Rationing critical care beds: a systematic review. Crit Care Med (2004) 2.86
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med (2015) 2.85
Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids. Crit Care Med (2010) 2.82
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Pulmonary arteriovenous malformations. Chest (2013) 2.77
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Attributable cost of catheter-associated bloodstream infections among intensive care patients in a nonteaching hospital. Crit Care Med (2006) 2.76
Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis. Thromb Haemost (2011) 2.75
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One (2012) 2.75
One-Year Outcomes in Caregivers of Critically Ill Patients. N Engl J Med (2016) 2.73
Facilitating clinician adherence to guidelines in the intensive care unit: A multicenter, qualitative study. Crit Care Med (2007) 2.72
Acute rehabilitation practices in critically ill children: a multicenter study. Pediatr Crit Care Med (2014) 2.71
Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: a randomized placebo controlled pilot trial (CANTREAT study). Intensive Care Med (2014) 2.70
Credibility of claims of subgroup effects in randomised controlled trials: systematic review. BMJ (2012) 2.69
Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69
Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort study. Crit Care Med (2008) 2.68
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Crit Care Med (2013) 2.68
Longitudinal changes in procalcitonin in a heterogeneous group of critically ill patients. Crit Care Med (2012) 2.65
Clinician predictions of intensive care unit mortality. Crit Care Med (2004) 2.65
Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit patients in a suburban medical center. Crit Care Med (2003) 2.59
An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods. J Clin Epidemiol (2004) 2.58
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Age of transfused blood in critically ill adults. N Engl J Med (2015) 2.52
Indications, complications, and management of inferior vena cava filters: the experience in 952 patients at an academic hospital with a level I trauma center. JAMA Intern Med (2013) 2.52
Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: a meta-analysis of randomized trials. Arch Intern Med (2007) 2.50
Diagnosis of DVT: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 2.50
Meta-analyses of therapies for postmenopausal osteoporosis. II. Meta-analysis of alendronate for the treatment of postmenopausal women. Endocr Rev (2002) 2.49
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Evidence based medicine has come a long way. BMJ (2004) 2.42
A persistent and diverse airway microbiota present during chronic obstructive pulmonary disease exacerbations. OMICS (2010) 2.42
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Probiotics in the critically ill: a systematic review of the randomized trial evidence. Crit Care Med (2012) 2.35
Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med (2011) 2.35
Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 2.28
Predicting deep venous thrombosis in pregnancy: out in "LEFt" field? Ann Intern Med (2009) 2.26
Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med (2015) 2.25
Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest (2013) 2.24