Rational combinations of immunotherapeutics that target discrete pathways.

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🔗 View Article (PMC 4019905)

Published in J Immunother Cancer on September 23, 2013

Authors

Stefani Spranger1, Thomas Gajewski2

Author Affiliations

1: Biological Sciences Division, Pathology, The University of Chicago, 929 E. 57th Street, GCIS W-423, Chicago, IL 60637, USA.
2: Department of Pathology and Department of Medicine, Section of Hematology/Oncology, The University of Chicago, 5841 S. Maryland Ave., MC2115, Chicago, IL 60637, USA.

Associated clinical trials:

Phase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067) | NCT01844505

A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With INCB024360 or Placebo in Subjects With Unresectable or Metastatic Melanoma | NCT01604889

1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | NCT00567931

A Dose-escalation Study in Subjects With Advanced Malignancies | NCT01195311

Vaccine Therapy With or Without Recombinant Interleukin-12 Followed by Daclizumab in Treating Patients With Metastatic Melanoma | NCT01307618

Ovarian Dendritic Cell Vaccine Trial | NCT00703105

NCT00617422

1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | NCT01191216

Vaccination Plus Ontak in Patients With Metastatic Melanoma | NCT00515528

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