APOBEC3 signature mutations in chronic lymphocytic leukemia.

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Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution. Nat Commun (2015) 0.90

AID/APOBEC deaminases and cancer. Oncoscience (2015) 0.89

AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells. Eur J Immunol (2014) 0.84

Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif. Oncotarget (2015) 0.80

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms. Annu Rev Genet (2015) 0.78

Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation. Cell Commun Signal (2017) 0.75

APOBEC3B expression in human leptomeninges and meningiomas. Oncol Lett (2016) 0.75

Signatures of mutational processes in human cancer. Nature (2013) 21.63

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature (2011) 13.18

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell (2013) 9.24

Molecular mechanisms of antibody somatic hypermutation. Annu Rev Biochem (2007) 6.92

APOBEC3B is an enzymatic source of mutation in breast cancer. Nature (2013) 5.18

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet (2013) 4.69

The AID/APOBEC family of nucleic acid mutators. Genome Biol (2008) 3.25

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. Elife (2013) 2.67

RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA. Biochim Biophys Acta (2000) 1.77

Mutagenic and epigenetic effects of DNA methylation. Mutat Res (1997) 1.38

High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia. Leukemia (2004) 1.09

Creative deaminases, self-inflicted damage, and genome evolution. Ann N Y Acad Sci (2012) 1.03

Activation-induced cytidine deaminase in antibody diversification and chromosome translocation. Adv Cancer Res (2012) 0.92

IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions. Blood (2012) 0.91

Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation. Leukemia (2006) 0.89