Published in Hum Mol Genet on June 06, 2014
DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites. J Biol Chem (2015) 0.96
Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders. EBioMedicine (2015) 0.84
Chronic Stress Increases Prefrontal Inhibition: A Mechanism for Stress-Induced Prefrontal Dysfunction. Biol Psychiatry (2016) 0.81
Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function. NPJ Schizophr (2016) 0.78
DISC1 causes associative memory and neurodevelopmental defects in fruit flies. Mol Psychiatry (2016) 0.78
The involvement of N-methyl-d-aspartate receptor (NMDAR) subunit NR1 in the pathophysiology of schizophrenia. Acta Biochim Biophys Sin (Shanghai) (2016) 0.77
Utility and validity of DISC1 mouse models in biological psychiatry. Neuroscience (2016) 0.77
A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons. Hum Mol Genet (2016) 0.77
Investigating the mechanism(s) underlying switching between states in bipolar disorder. Eur J Pharmacol (2015) 0.77
Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol (2015) 0.75
Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring. Mol Brain (2016) 0.75
Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice. Neurobiol Dis (2017) 0.75
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The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology (Berl) (1985) 7.53
Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet (2000) 7.16
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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) (2001) 5.67
The AMP-activated protein kinase pathway--new players upstream and downstream. J Cell Sci (2004) 5.65
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell (2009) 5.34
Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci (1997) 5.30
Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J Neurosci (2003) 4.86
Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J (2002) 4.83
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet (2001) 4.77
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell (2007) 4.76
The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev (2005) 4.64
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml. Nucleic Acids Res (1997) 4.40
NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J Neurosci (2007) 4.35
SUnSET, a nonradioactive method to monitor protein synthesis. Nat Methods (2009) 4.12
Association within a family of a balanced autosomal translocation with major mental illness. Lancet (1990) 3.94
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol (2005) 3.89
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus. Genes Dev (2003) 3.85
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat Cell Biol (2005) 3.80
Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia. Arch Gen Psychiatry (2000) 3.44
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Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys (1993) 3.26
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eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature (2007) 3.07
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci U S A (2007) 3.02
FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012) 2.95
Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci (2011) 2.89
Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry (1992) 2.72
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Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology (1995) 2.53
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry (2007) 2.53
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev (2006) 2.47
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
Molecular mechanisms of fragile X syndrome: a twenty-year perspective. Annu Rev Pathol (2011) 2.39
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci U S A (2008) 2.37
Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology (1997) 2.20
The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci (2012) 2.16
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Exaggerated translation causes synaptic and behavioural aberrations associated with autism. Nature (2012) 1.98
Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: clinical, protein, and cell type-specific features. Am J Psychiatry (2011) 1.91
Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am J Psychiatry (2000) 1.75
Single-copy gene detection using branched DNA (bDNA) in situ hybridization. J Histochem Cytochem (2001) 1.69
Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Hum Mol Genet (2006) 1.61
Essential fatty acids in visual and brain development. Lipids (2001) 1.60
Translational efficiency of EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location. Biotechniques (2006) 1.60
Activity-dependent development of inhibitory synapses and innervation pattern: role of GABA signalling and beyond. J Physiol (2009) 1.53
Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95. Cell (2012) 1.48
From mTOR to cognition: molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis. J Intellect Disabil Res (2009) 1.37
Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet (2011) 1.36
Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology (2006) 1.33
Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease. J Neurosci (2008) 1.32
Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport (2001) 1.31
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Mol Psychiatry (2010) 1.28
Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1). Genomics (2002) 1.22
MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets. Acta Histochem (2012) 1.21
Heritable differences in the dopaminergic regulation of sensorimotor gating. II. Temporal, pharmacologic and generational analyses of apomorphine effects on prepulse inhibition. Psychopharmacology (Berl) (2003) 1.20
Habituation of the Blink reflex in normals and schizophrenic patients. Psychophysiology (1982) 1.19
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Effects of noncompetitive NMDA receptor blockade on anterior cingulate cerebral blood flow in volunteers with schizophrenia. Neuropsychopharmacology (2005) 1.08
Epigenetic silencing of nucleolar rRNA genes in Alzheimer's disease. PLoS One (2011) 1.07
A metabolic throttle regulates the epigenetic state of rDNA. Cell (2008) 1.06
Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia. Br J Haematol (2012) 1.05
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. Mol Psychiatry (2013) 1.05
mRNA translation and energy metabolism in cancer: the role of the MAPK and mTORC1 pathways. Cold Spring Harb Symp Quant Biol (2011) 1.03
Recessive hereditary methaemoglobinaemia, type II: delineation of the clinical spectrum. Brain (2008) 1.01
Insoluble DISC1-Boymaw fusion proteins generated by DISC1 translocation. Mol Psychiatry (2010) 0.98
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins. Hum Mol Genet (2012) 0.97
Effects of weekly blood collection in C57BL/6 mice. J Am Assoc Lab Anim Sci (2011) 0.96
Pramipexole effects on startle gating in rats and normal men. Psychopharmacology (Berl) (2009) 0.93
Four factors underlying mouse behavior in an open field. Behav Brain Res (2012) 0.91
Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia. PLoS One (2013) 0.90
Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease. Cell Death Differ (2011) 0.89
Translation's coming of age. Mol Syst Biol (2011) 0.89
A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications. J Proteome Res (2009) 0.89
System-wide immunohistochemical analysis of protein co-localization. PLoS One (2012) 0.89
Attenuation of high sweet solution preference by mood stabilizers: a possible mouse model for the increased reward-seeking domain of mania. J Neurosci Methods (2008) 0.87
Promoter variant in the GRK3 gene associated with bipolar disorder alters gene expression. Biol Psychiatry (2008) 0.87
Does disrupted-in-schizophrenia (DISC1) generate fusion transcripts? Mol Psychiatry (2008) 0.87
Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review. Schizophr Res (2013) 0.87
The effect of pregabalin on sensorimotor gating in 'low' gating humans and mice. Neuropharmacology (2012) 0.80
Inhibition of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) endocytosis by ouabain in human endothelial cells. FEBS Lett (2006) 0.79