Published in Proc Natl Acad Sci U S A on February 01, 1989
Complete MHC haplotype sequencing for common disease gene mapping. Genome Res (2004) 12.09
Concerted and birth-and-death evolution of multigene families. Annu Rev Genet (2005) 6.37
Low nucleotide diversity in man. Genetics (1991) 5.83
Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1. J Virol (1990) 5.20
Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics (1990) 5.11
Positive Darwinian evolution in human influenza A viruses. Proc Natl Acad Sci U S A (1991) 4.78
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS Genet (2006) 2.80
The importance of immune gene variability (MHC) in evolutionary ecology and conservation. Front Zool (2005) 2.80
Selectionism and neutralism in molecular evolution. Mol Biol Evol (2005) 2.64
Polymorphism and balancing selection at major histocompatibility complex loci. Genetics (1992) 2.34
Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. PLoS Genet (2010) 2.14
Natural selection drives Drosophila immune system evolution. Genetics (2003) 2.13
Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population. Proc Natl Acad Sci U S A (1998) 2.13
Mutation rate varies among alleles at a microsatellite locus: phylogenetic evidence. Proc Natl Acad Sci U S A (1996) 1.96
Reliabilities of identifying positive selection by the branch-site and the site-prediction methods. Proc Natl Acad Sci U S A (2009) 1.94
Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques. Immunogenetics (2007) 1.87
Hypervariability generated by natural selection in an extracellular complement-inhibiting protein of serotype M1 strains of group A Streptococcus. Proc Natl Acad Sci U S A (1998) 1.85
Adaptive evolution in two large families of ubiquitin-ligase adapters in nematodes and plants. Genome Res (2006) 1.84
Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli. Mol Microbiol (2006) 1.82
Evidence for balancing selection operating at the het-c heterokaryon incompatibility locus in a group of filamentous fungi. Proc Natl Acad Sci U S A (1998) 1.75
Targets of balancing selection in the human genome. Mol Biol Evol (2009) 1.69
Association between major histocompatibility complex class IIB alleles and resistance to Aeromonas salmonicida in Atlantic salmon. Proc Biol Sci (2001) 1.64
Ancient haplotypes of the HLA Class II region. Genome Res (2005) 1.62
MHC polymorphism under host-pathogen coevolution. Immunogenetics (2004) 1.61
Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions. Genetics (1991) 1.60
Punctuated equilibrium and positive Darwinian evolution in vesicular stomatitis virus. Proc Natl Acad Sci U S A (1993) 1.49
Positive selection and rates of evolution in immunodeficiency viruses from humans and chimpanzees. Proc Natl Acad Sci U S A (1996) 1.44
The functional genomic distribution of protein divergence in two animal phyla: coevolution, genomic conflict, and constraint. Genome Res (2004) 1.41
Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees. Proc Natl Acad Sci U S A (2002) 1.39
Signatures of demographic history and natural selection in the human major histocompatibility complex Loci. Genetics (2006) 1.37
Large-scale, lineage-specific expansion of a bric-a-brac/tramtrack/broad complex ubiquitin-ligase gene family in rice. Plant Cell (2007) 1.36
Evolution of the mitochondrial DNA control region in the mbuna (Cichlidae) species flock of Lake Malawi, East Africa. J Mol Evol (1997) 1.35
Elevated polymorphism and divergence in the class C scavenger receptors of Drosophila melanogaster and D. simulans. Genetics (2005) 1.34
Polymorphisms in Anopheles gambiae immune genes associated with natural resistance to Plasmodium falciparum. PLoS Pathog (2010) 1.34
Gene duplication and fragmentation in the zebra finch major histocompatibility complex. BMC Biol (2010) 1.34
Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes. Genetics (2005) 1.31
Primitive synteny of vertebrate major histocompatibility complex class I and class II genes. Proc Natl Acad Sci U S A (2000) 1.31
Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations. Philos Trans R Soc Lond B Biol Sci (2012) 1.28
SNP profile within the human major histocompatibility complex reveals an extreme and interrupted level of nucleotide diversity. Genome Res (2000) 1.24
Heterozygosity at individual amino acid sites: extremely high levels for HLA-A and -B genes. Proc Natl Acad Sci U S A (1991) 1.23
Heterozygote advantage fails to explain the high degree of polymorphism of the MHC. Immunogenetics (2004) 1.22
New methods for detecting positive selection at single amino acid sites. J Mol Evol (2004) 1.21
Regulation of major histocompatibility complex class II gene expression, genetic variation and disease. Genes Immun (2009) 1.21
Genetic drift can dominate short-term human immunodeficiency virus type 1 nef quasispecies evolution in vivo. J Virol (1997) 1.20
Discrimination of MHC-derived odors by untrained mice is consistent with divergence in peptide-binding region residues. Proc Natl Acad Sci U S A (2002) 1.18
Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex. Proc Natl Acad Sci U S A (1990) 1.18
Human adaptive evolution at Myostatin (GDF8), a regulator of muscle growth. Am J Hum Genet (2006) 1.16
Adaptive evolution in the SRZ chemoreceptor families of Caenorhabditis elegans and Caenorhabditis briggsae. Proc Natl Acad Sci U S A (2005) 1.16
Diversity of Mhc class I and IIB genes in house sparrows (Passer domesticus). Immunogenetics (2004) 1.12
Immunogenetics as a tool in anthropological studies. Immunology (2011) 1.11
Accelerated evolution of Trimeresurus flavoviridis venom gland phospholipase A2 isozymes. Proc Natl Acad Sci U S A (1993) 1.08
HLA-DR and -DQ gene polymorphism in West Africans is twice as extensive as in north European Caucasians: evolutionary implications. Proc Natl Acad Sci U S A (1991) 1.07
Strong balancing selection at HLA loci: evidence from segregation in South Amerindian families. Proc Natl Acad Sci U S A (1997) 1.06
Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark. Proc Natl Acad Sci U S A (1994) 1.06
Gene duplication and gene conversion in class II MHC genes of New Zealand robins (Petroicidae). Immunogenetics (2004) 1.05
Fifty-million-year-old polymorphism at an immunoglobulin variable region gene locus in the rabbit evolutionary lineage. Proc Natl Acad Sci U S A (1999) 1.05
Evolutionary conservation of major histocompatibility complex-DR/peptide/T cell interactions in primates. J Exp Med (1993) 1.04
Ancestral polymorphism of Mhc class II genes in mice: implications for balancing selection and the mammalian molecular clock. Genetics (1997) 1.04
HLA DNA sequence variation among human populations: molecular signatures of demographic and selective events. PLoS One (2011) 1.04
Contrasting roles of interallelic recombination at the HLA-A and HLA-B loci. Genetics (1993) 1.03
Distinct evolutionary strategies of human leucocyte antigen loci in pathogen-rich environments. Philos Trans R Soc Lond B Biol Sci (2012) 1.02
Evolution of the major histocompatibility complex: isolation of class II A cDNA clones from the cartilaginous fish. Proc Natl Acad Sci U S A (1992) 1.02
No evidence for major histocompatibility complex-dependent mating patterns in a free-living ruminant population. Proc Biol Sci (1997) 1.02
Tertiary windowing to detect positive diversifying selection. J Mol Evol (2005) 1.01
Effects of natural selection and gene conversion on the evolution of human glycophorins coding for MNS blood polymorphisms in malaria-endemic African populations. Am J Hum Genet (2011) 1.00
High level of functional polymorphism indicates a unique role of natural selection at human immune system loci. Immunogenetics (2005) 0.98
Evolution of major histocompatibility complex class II allelic diversity: direct descent in mice and humans. Proc Natl Acad Sci U S A (1992) 0.98
Full-length sequence analysis of the HLA-DRB1 locus suggests a recent origin of alleles. Immunogenetics (2007) 0.98
Evolutionary analysis of classical HLA class I and II genes suggests that recent positive selection acted on DPB1*04:01 in Japanese population. PLoS One (2012) 0.98
Selection, diversity and evolutionary patterns of the MHC class II DAB in free-ranging Neotropical marsupials. BMC Genet (2008) 0.98
Study of cynomolgus monkey (Macaca fascicularis) DRA polymorphism in four populations. Immunogenetics (2010) 0.97
Natural selection acts on Atlantic salmon major histocompatibility (MH) variability in the wild. Proc Biol Sci (2007) 0.97
Sympatric and allopatric divergence of MHC genes in threespine stickleback. PLoS One (2010) 0.96
Amplification of major histocompatibility complex class II gene diversity by intraexonic recombination. Proc Natl Acad Sci U S A (1991) 0.96
Gene structure of mouse BIT/SHPS-1. Biochem J (1999) 0.96
Selection, hitchhiking and disequilibrium analysis at three linked loci with application to HLA data. Genetics (1991) 0.94
Evidence of positive Darwinian selection in Omp85, a highly conserved bacterial outer membrane protein essential for cell viability. J Mol Evol (2005) 0.94
Patterns of variability at the major histocompatibility class II alpha locus in Atlantic salmon contrast with those at the class I locus. Immunogenetics (2005) 0.93
Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome. Immunogenetics (2003) 0.93
Molecular and immunological significance of chimpanzee major histocompatibility complex haplotypes for hepatitis C virus immune response and vaccination studies. J Virol (2002) 0.92
Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes. BMC Evol Biol (2007) 0.92
Low major histocompatibility complex class II diversity in European and North American moose. Proc Natl Acad Sci U S A (1995) 0.91
Adaptive molecular evolution of the Major Histocompatibility Complex genes, DRA and DQA, in the genus Equus. BMC Evol Biol (2011) 0.91
Microevolution in fimH gene of mucosa-associated Escherichia coli strains isolated from pediatric patients with inflammatory bowel disease. Infect Immun (2012) 0.90
A family of rapidly evolving genes from the sex reversal critical region in Xp21. Mamm Genome (1995) 0.90
Gene duplication, allelic diversity, selection processes and adaptive value of MHC class II DRB genes of the bank vole, Clethrionomys glareolus. Immunogenetics (2007) 0.90
DR haplotype diversity of the cynomolgus macaque as defined by its transcriptome. Immunogenetics (2011) 0.90
Ancient interlocus exon exchange in the history of the HLA-A locus. Genetics (1989) 0.90
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. J Clin Invest (2014) 0.90
Signals of major histocompatibility complex overdominance in a wild salmonid population. Proc Biol Sci (2009) 0.89
Sequencing of the core MHC region of black grouse (Tetrao tetrix) and comparative genomics of the galliform MHC. BMC Genomics (2012) 0.89
Variation in MHC genotypes in two populations of house sparrow (Passer domesticus) with different population histories. Ecol Evol (2011) 0.88
Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations. Proc Biol Sci (2016) 0.88
Major histocompatibility complex variation in the endangered Przewalski's horse. Genetics (1999) 0.88
Polydnavirus-facilitated endoparasite protection against host immune defenses. Proc Natl Acad Sci U S A (1995) 0.88
Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus). BMC Evol Biol (2009) 0.88
Contrasting epidemic histories reveal pathogen-mediated balancing selection on class II MHC diversity in a wild songbird. PLoS One (2012) 0.87
Mhc class II diversity and balancing selection in greater prairie-chickens. Genetica (2009) 0.87
Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol Biol Evol (1986) 36.06
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection. Nature (1988) 15.05
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature (1987) 12.43
A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature (1988) 5.99
The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides. Science (1987) 5.32
Evolutionary significance of the HL-A system. Nature (1972) 4.06
Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex. Nature (1975) 3.49
The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism. Folia Biol (Praha) (1968) 3.43
HLA-A and B polymorphisms predate the divergence of humans and chimpanzees. Nature (1988) 3.21
DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. EMBO J (1985) 3.20
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 3.09
The murine E alpha immune response gene. Cell (1983) 2.86
Genetic variability maintained by mutation and overdominant selection in finite populations. Genetics (1981) 2.79
MHC polymorphism pre-dating speciation. Nature (1988) 2.70
Methods for computing the standard errors of branching points in an evolutionary tree and their application to molecular data from humans and apes. Mol Biol Evol (1985) 2.58
Regions of allelic hypervariability in the murine A alpha immune response gene. Cell (1983) 2.53
Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon. Cell (1983) 2.42
Isotypic and allotypic variation of human class II histocompatibility antigen alpha-chain genes. Nature (1984) 2.37
Mutations and selection in the generation of class II histocompatibility antigen polymorphism. EMBO J (1984) 2.34
Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta. Proc Natl Acad Sci U S A (1984) 2.19
Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains. EMBO J (1984) 2.18
Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18
Evolution of the major histocompatibility complex. Crit Rev Immunol (1986) 2.16
Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science (1983) 2.12
"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta. Proc Natl Acad Sci U S A (1985) 1.93
Allelic variation in the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci U S A (1987) 1.92
The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex. EMBO J (1984) 1.87
Sequence of gene and cDNA encoding murine major histocompatibility complex class II gene A beta 2. J Biol Chem (1985) 1.66
I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif. J Immunol (1988) 1.61
Inherited histocompatibility changes in progeny of irradiated and unirradiated inbred mice. Genet Res (1965) 1.58
Isolation and characterization of a cDNA clone for the murine I-E beta polypeptide chain. Proc Natl Acad Sci U S A (1983) 1.54
Genetics and expression of mouse Ia antigens. Annu Rev Immunol (1985) 1.45
The origin of MHC class II gene polymorphism within the genus Mus. Nature (1988) 1.43
Sequence analysis and structure-function correlations of murine q, k, u, s, and f haplotype I-A beta cDNA clones. Proc Natl Acad Sci U S A (1986) 1.39
The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region. Nature (1983) 1.31
The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas. Proc Natl Acad Sci U S A (1985) 1.21
Complete sequence of the HLA DQ alpha and DQ beta cDNA from a DR5/DQw3 cell line. J Immunol (1987) 1.18
The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions. EMBO J (1985) 1.17
HLA-DR2 subtypes form an additional supertypic family of DR beta alleles. Proc Natl Acad Sci U S A (1987) 1.03
A molecular basis for the Ia.2 and Ia.19 antigenic determinants. Proc Natl Acad Sci U S A (1985) 0.99
MHC class II sequences of an HLA-DR2 narcoleptic. Immunogenetics (1988) 0.94
DQw1 beta gene from HLA-DR2-Dw12 consists of six exons and expresses multiple DQw1 beta polypeptides through alternative splicing. Immunogenetics (1987) 0.94
High codon-usage changes in mammalian genes. Mol Biol Evol (1988) 0.92
Gene clusters and the evolution of the major histocompatibility system. Philos Trans R Soc Lond B Biol Sci (1986) 0.92
Molecular organization of the class II genes of the human and mouse major histocompatibility complexes. Oxf Surv Eukaryot Genes (1986) 0.91
Sequence and evolution of HLA-DR7- and -DRw53-associated beta-chain genes. Proc Natl Acad Sci U S A (1987) 0.89
A newly characterized HLA-DP beta-chain allele. Evidence for DP beta heterogeneity within the DPw4 specificity. J Immunol (1988) 0.88
Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR beta-chain cDNA sequences. Proc Natl Acad Sci U S A (1987) 0.82
Allelic forms of the alpha- and beta-chain genes encoding DQw1-positive heterodimers. Immunogenetics (1987) 0.82
Molecular variation of human major histocompatibility complex DQw3 beta-chains. J Immunol (1987) 0.81
The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol (1987) 266.90
Mathematical model for studying genetic variation in terms of restriction endonucleases. Proc Natl Acad Sci U S A (1979) 41.08
MEGA2: molecular evolutionary genetics analysis software. Bioinformatics (2001) 38.50
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol (1993) 38.03
MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers. Comput Appl Biosci (1994) 28.25
Analysis of gene diversity in subdivided populations. Proc Natl Acad Sci U S A (1973) 26.31
Statistical studies on protein polymorphism in natural populations. I. Distribution of single locus heterozygosity. Genetics (1977) 17.08
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection. Nature (1988) 15.05
Phylogenetic test of the molecular clock and linearized trees. Mol Biol Evol (1995) 14.60
Gene differences between Caucasian, Negro, and Japanese populations. Science (1972) 12.11
Sampling variances of heterozygosity and genetic distance. Genetics (1974) 11.91
A new method of inference of ancestral nucleotide and amino acid sequences. Genetics (1995) 10.23
DNA polymorphism detectable by restriction endonucleases. Genetics (1981) 10.13
The theory of genetic distance and evolution of human races. Jinrui Idengaku Zasshi (1978) 8.80
Relationships between gene trees and species trees. Mol Biol Evol (1988) 8.63
Accuracy of estimated phylogenetic trees from molecular data. II. Gene frequency data. J Mol Evol (1983) 7.45
Limitations of the evolutionary parsimony method of phylogenetic analysis. Mol Biol Evol (1990) 5.92
F-statistics and analysis of gene diversity in subdivided populations. Ann Hum Genet (1977) 5.89
Estimation of fixation indices and gene diversities. Ann Hum Genet (1983) 5.67
Genetic structure of human populations. II. Differentiation of blood group gene frequencies among isolated populations. Heredity (Edinb) (1966) 5.55
Positive Darwinian selection after gene duplication in primate ribonuclease genes. Proc Natl Acad Sci U S A (1998) 5.54
Maximum likelihood estimation of the number of nucleotide substitutions from restriction sites data. Genetics (1983) 5.48
Estimation of evolutionary distance between nucleotide sequences. Mol Biol Evol (1984) 5.39
Linkage disequilibrium in subdivided populations. Genetics (1973) 5.22
Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci. Genetics (1990) 5.11
Genetic distances and reconstruction of phylogenetic trees from microsatellite DNA. Genetics (1996) 4.55
Drift variances of heterozygosity and genetic distance in transient states. Genet Res (1975) 4.45
Molecular phylogeny and divergence times of drosophilid species. Mol Biol Evol (1995) 4.33
Pseudogenes as a paradigm of neutral evolution. Nature (1981) 4.33
Genetic distance and electrophoretic identity of proteins between taxa. J Mol Evol (1973) 4.19
Modification of linkage intensity by natural selection. Genetics (1967) 3.99
Non-random association between electromorphs and inversion chromosomes in finite populations. Genet Res (1980) 3.69
Gene genealogy and variance of interpopulational nucleotide differences. Genetics (1985) 3.64
Infinite allele model with varying mutation rate. Proc Natl Acad Sci U S A (1976) 3.56
Estimation of average number of nucleotide substitutions when the rate of substitution varies with nucleotide. J Mol Evol (1982) 3.45
Population dynamics of sex-determining alleles in honey bees and self-incompatibility alleles in plants. Genetics (1979) 3.27
Probability of identical monomorphism in related species. Genet Res (1975) 2.91
Efficiencies of fast algorithms of phylogenetic inference under the criteria of maximum parsimony, minimum evolution, and maximum likelihood when a large number of sequences are used. Mol Biol Evol (2000) 2.86
Genetic variability maintained by mutation and overdominant selection in finite populations. Genetics (1981) 2.79
Genic variation within and between the three major races of man, Caucasoids, Negroids, and Mongoloids. Am J Hum Genet (1974) 2.77
The frequency distribution of lethal chromosomes in finite populations. Proc Natl Acad Sci U S A (1968) 2.76
Statistical Studies on Protein Polymorphism in Natural Populations. III. Distribution of Allele Frequencies and the Number of Alleles per Locus. Genetics (1980) 2.76
Theoretical foundation of the minimum-evolution method of phylogenetic inference. Mol Biol Evol (1993) 2.74
Letters to the editors: Lewontin-Krakauer test for neutral genes. Genetics (1975) 2.59
Models of evolution of reproductive isolation. Genetics (1983) 2.58
Phylogenetic analysis of polymorphic DNA sequences at the Adh locus in Drosophila melanogaster and its sibling species. J Mol Evol (1985) 2.48
Interior-branch and bootstrap tests of phylogenetic trees. Mol Biol Evol (1995) 2.45
Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules. Mol Biol Evol (1990) 2.41
Testing the neutral mutation hypothesis by distribution of single locus heterozygosity. Nature (1976) 2.37
Accumulation of mutations in sexual and asexual populations. Genet Res (1987) 2.30
Genetic structure of human populations. I. Local differentiation of blood group gene frequencies in Japan. Heredity (Edinb) (1966) 2.26
The number of nucleotides required to determine the branching order of three species, with special reference to the human-chimpanzee-gorilla divergence. J Mol Evol (1986) 2.25
Accuracies of ancestral amino acid sequences inferred by the parsimony, likelihood, and distance methods. J Mol Evol (1997) 2.23
Identity of genes by descent within and between populations under mutation and migration pressures. Theor Popul Biol (1972) 2.19
Positive darwinian selection observed at the variable-region genes of immunoglobulins. Mol Biol Evol (1989) 2.17
Estimation of mutation rate from rare protein variants. Am J Hum Genet (1977) 2.15
Statistical Studies on Protein Polymorphism in Natural Populations II. Gene Differentiation between Populations. Genetics (1978) 2.13
Evolution of human races at the gene level. Prog Clin Biol Res (1982) 2.13
Note on genetic drift and estimation of effective population size. Genetics (1984) 2.07
Relative efficiencies of the maximum parsimony and distance-matrix methods in obtaining the correct phylogenetic tree. Mol Biol Evol (1988) 2.03
Total number of individuals affected by a single deleterious mutation in a finite population. Am J Hum Genet (1972) 1.98
Small-sample tests of episodic adaptive evolution: a case study of primate lysozymes. Mol Biol Evol (1997) 1.97
Linkage modifications and sex difference in recombination. Genetics (1969) 1.96
Stable linkage disequilibrium without epistasis in subdivided populations. Theor Popul Biol (1974) 1.93
Extinction time of deleterious mutant genes in large populations. Theor Popul Biol (1971) 1.87
Polymorphism and evolution of influenza A virus genes. Mol Biol Evol (1986) 1.86
Gene duplication and nucleotide substitution in evolution. Nature (1969) 1.85
Efficiencies of different genes and different tree-building methods in recovering a known vertebrate phylogeny. Mol Biol Evol (1996) 1.84
Mean and variance of FST in a finite number of incompletely isolated populations. Theor Popul Biol (1977) 1.79
Divergent evolution and evolution by the birth-and-death process in the immunoglobulin VH gene family. Mol Biol Evol (1994) 1.77
Effective population size when fertility is inherited. Genet Res (1966) 1.76
Variability and heritability of human fertility. Ann Hum Genet (1970) 1.71
The transient distribution of allele frequencies under mutation pressure. Genet Res (1976) 1.70
A note on positive identification of paternity by using genetic markers. Hum Hered (1983) 1.66
Evolution of Antennapedia-class homeobox genes. Genetics (1996) 1.63
Circumsporozoite protein genes of malaria parasites (Plasmodium spp.): evidence for positive selection on immunogenic regions. Genetics (1991) 1.60
Probability of fixation and mean fixation time of an overdominant mutation. Genetics (1973) 1.57
Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site. Mol Biol Evol (1994) 1.57
Relative efficiencies of the maximum-likelihood, neighbor-joining, and maximum-parsimony methods when substitution rate varies with site. Mol Biol Evol (1994) 1.57
Evolution of the major histocompatibility complex: independent origin of nonclassical class I genes in different groups of mammals. Mol Biol Evol (1989) 1.56
Persistence of common alleles in two related populations or species. Genetics (1977) 1.54
Evolutionary change of linkage intensity. Nature (1968) 1.54
Relative efficiencies of the maximum-parsimony and distance-matrix methods of phylogeny construction for restriction data. Mol Biol Evol (1991) 1.53
Four-cluster analysis: a simple method to test phylogenetic hypotheses. Mol Biol Evol (1995) 1.48
Dynamics of gene differentiation between incompletely isolated populations of unequal sizes. Theor Popul Biol (1974) 1.47
F and g statistics in the finite island model. Genetics (1984) 1.46
Accuracy of estimated phylogenetic trees from molecular data. I. Distantly related species. J Mol Evol (1982) 1.45
Reliabilities of parsimony-based and likelihood-based methods for detecting positive selection at single amino acid sites. Mol Biol Evol (2001) 1.44
Effective size of human populations. Am J Hum Genet (1970) 1.41
ADAPTSITE: detecting natural selection at single amino acid sites. Bioinformatics (2001) 1.40
Total number of individuals affected by a single deleterious mutation in large populations. Theor Popul Biol (1971) 1.39
Statistical properties of the ordinary least-squares, generalized least-squares, and minimum-evolution methods of phylogenetic inference. J Mol Evol (1992) 1.35
Drift variances of FST and GST statistics obtained from a finite number of isolated populations. Theor Popul Biol (1977) 1.31
Frequency changes of new inversions in populations under mutation-selection equilibria. Genetics (1967) 1.29
Effects of restricted population size and increase in mutation rate on the genetic variation of quantitative characters. Genetics (1966) 1.26
Maintenance of MHC polymorphism. Nature (1992) 1.25
Tests of applicability of several substitution models for DNA sequence data. Mol Biol Evol (1995) 1.24
Models of host-parasite interaction and MHC polymorphism. Genetics (1992) 1.19