PubRank

Mingdong Huang

Author PubWeight™ 43.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex. Structure 2008 1.93
2 Structure of human urokinase plasminogen activator in complex with its receptor. Science 2006 1.84
3 Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood 2012 1.26
4 Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions. J Exp Med 2002 1.25
5 Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes. Nat Struct Mol Biol 2008 1.23
6 Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy. J Biol Chem 2010 1.14
7 Effect of human serum albumin on drug metabolism: structural evidence of esterase activity of human serum albumin. J Struct Biol 2006 1.07
8 Crystal structure of the urokinase receptor in a ligand-free form. J Mol Biol 2012 1.03
9 Amine-functionalized lanthanide-doped zirconia nanoparticles: optical spectroscopy, time-resolved fluorescence resonance energy transfer biodetection, and targeted imaging. J Am Chem Soc 2012 0.99
10 A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography. J Struct Biol 2007 0.98
11 Amine-functionalized lanthanide-doped KGdF4 nanocrystals as potential optical/magnetic multimodal bioprobes. J Am Chem Soc 2011 0.97
12 Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. J Biol Chem 2011 0.96
13 Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIII. J Mol Biol 2007 0.96
14 Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor. J Biol Chem 2011 0.94
15 Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J Biol Chem 2010 0.94
16 An anti-urokinase plasminogen activator receptor (uPAR) antibody: crystal structure and binding epitope. J Mol Biol 2006 0.90
17 Lanthanide-doped upconversion nanoparticles electrostatically coupled with photosensitizers for near-infrared-triggered photodynamic therapy. Nanoscale 2014 0.88
18 Structural mechanism of ring-opening reaction of glucose by human serum albumin. J Biol Chem 2013 0.88
19 Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1. J Struct Biol 2007 0.88
20 Structural basis of transport of lysophospholipids by human serum albumin. Biochem J 2009 0.87
21 Structural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist. Chem Biol 2013 0.87
22 Lanthanide-doped LiLuF(4) upconversion nanoprobes for the detection of disease biomarkers. Angew Chem Int Ed Engl 2014 0.87
23 Sub-10 nm lanthanide-doped CaF2 nanoprobes for time-resolved luminescent biodetection. Angew Chem Int Ed Engl 2013 0.86
24 Structural evidence of perfluorooctane sulfonate transport by human serum albumin. Chem Res Toxicol 2012 0.86
25 Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. BMC Struct Biol 2011 0.84
26 Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J Biol Chem 2013 0.84
27 Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs. Mol Pharmacol 2011 0.83
28 An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg2+. Biochem Biophys Res Commun 2006 0.82
29 Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X. Biochem J 2010 0.81
30 Structural basis for therapeutic intervention of uPA/uPAR system. Curr Drug Targets 2011 0.81
31 A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin. Protein Sci 2011 0.81
32 Pentalysine beta-carbonylphthalocyanine zinc: an effective tumor-targeting photosensitizer for photodynamic therapy. ChemMedChem 2010 0.80
33 A new type of dye-sensitized solar cell with a multilayered photoanode prepared by a film-transfer technique. Adv Mater 2011 0.80
34 Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies. Biochem J 2011 0.79
35 Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix). FEBS Lett 2012 0.78
36 Bicyclic peptide inhibitor of urokinase-type plasminogen activator: mode of action. Chembiochem 2013 0.78
37 Enhanced photodynamic efficacy of zinc phthalocyanine by conjugating to heptalysine. Bioconjug Chem 2012 0.78
38 Lanthanide-doped luminescent nano-bioprobes for the detection of tumor markers. Nanoscale 2015 0.78
39 The binding mechanism of a peptidic cyclic serine protease inhibitor. J Mol Biol 2011 0.78
40 Detection of active matriptase using a biotinylated chloromethyl ketone peptide. PLoS One 2013 0.78
41 Expression, purification and characterization of recombinant Jerdonitin, a P-II class snake venom metalloproteinase comprising metalloproteinase and disintegrin domains. Toxicon 2009 0.77
42 Receptor-targeting phthalocyanine photosensitizer for improving antitumor photocytotoxicity. PLoS One 2012 0.77
43 Challenges for drug discovery - a case study of urokinase receptor inhibition. Comb Chem High Throughput Screen 2009 0.77
44 Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata. J Struct Biol 2008 0.76
45 Purification and preliminary crystallographic analysis of a Penicillium expansum lipase. Biochim Biophys Acta 2005 0.76
46 Lanthanide-doped NaScF4 nanoprobes: crystal structure, optical spectroscopy and biodetection. Nanoscale 2013 0.76
47 X-ray sequence and crystal structure of luffaculin 1, a novel type 1 ribosome-inactivating protein. BMC Struct Biol 2007 0.76
48 Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem J 2013 0.76
49 Urokinase-type plasminogen activator-like proteases in teleosts lack genuine receptor-binding epidermal growth factor-like domains. J Biol Chem 2012 0.75
50 Crystallization of an anti-factor IX antibody and its complex. Acta Crystallogr D Biol Crystallogr 2005 0.75
51 Optimization of crystals of an inhibitory antibody of urokinase plasminogen activator receptor (uPAR) with hydrogen peroxide and low protein concentration. Protein Pept Lett 2005 0.75
52 Phthalocyanine-Biomolecule Conjugated Photosensitizers for Targeted Photodynamic Therapy and Imaging. Curr Drug Metab 2015 0.75
53 Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD. Proteins 2010 0.75
54 A structural mechanism of flavonoids in inhibiting serine proteases. Food Funct 2017 0.75
55 Dissolution-enhanced luminescent bioassay based on inorganic lanthanide nanoparticles. Angew Chem Int Ed Engl 2014 0.75
56 Evaluation of interactions between urokinase plasminogen and inhibitors using molecular dynamic simulation and free-energy calculation. J Phys Chem A 2014 0.75