Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.

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Published in Genes Dev on June 15, 2014

Authors

Grace J Liu1, Luisa Cimmino1, Julian G Jude2, Yifang Hu3, Matthew T Witkowski1, Mark D McKenzie1, Mutlu Kartal-Kaess1, Sarah A Best1, Laura Tuohey1, Yang Liao4, Wei Shi4, Charles G Mullighan5, Michael A Farrar6, Stephen L Nutt7, Gordon K Smyth8, Johannes Zuber2, Ross A Dickins1

Author Affiliations

1: Molecular Medicine Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia;
2: Research Institute of Molecular Pathology, Vienna Biocenter, A-1030 Vienna, Austria;
3: Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia;
4: Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia; Department of Computing and Information Systems, University of Melbourne, Parkville, Victoria 3010, Australia;
5: Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA;
6: Department of Laboratory Medicine and Pathology, Center for Immunology, The Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA;
7: Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia; Molecular Immunology Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia;
8: Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia; Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria 3010, Australia.

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