| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The genome sequence of Drosophila melanogaster.
|
Science
|
2000
|
74.32
|
|
2
|
Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group.
|
Lancet
|
1998
|
4.54
|
|
3
|
ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results.
|
AIDS
|
2001
|
3.35
|
|
4
|
Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.
|
Antimicrob Agents Chemother
|
1997
|
2.57
|
|
5
|
Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients.
|
J Virol
|
2001
|
2.25
|
|
6
|
ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease.
|
Antimicrob Agents Chemother
|
1998
|
2.23
|
|
7
|
The proteases and pathogenicity of parasitic protozoa.
|
Annu Rev Microbiol
|
1993
|
1.96
|
|
8
|
Structure-based inhibitor design by using protein models for the development of antiparasitic agents.
|
Proc Natl Acad Sci U S A
|
1993
|
1.82
|
|
9
|
Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteers.
|
Antimicrob Agents Chemother
|
1998
|
1.60
|
|
10
|
Ritonavir and saquinavir combination therapy for the treatment of HIV infection.
|
AIDS
|
1999
|
1.58
|
|
11
|
The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir.
|
AIDS
|
1998
|
1.43
|
|
12
|
Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir.
|
Clin Pharmacol Ther
|
1998
|
1.40
|
|
13
|
Recent developments in HIV protease inhibitor therapy.
|
Antiviral Res
|
1998
|
1.33
|
|
14
|
Improvement in cell-mediated immune function during potent anti-human immunodeficiency virus therapy with ritonavir plus saquinavir.
|
J Infect Dis
|
1998
|
1.18
|
|
15
|
Highly purified pea chloroplast RNA polymerase transcribes both rRNA and mRNA genes.
|
Eur J Biochem
|
1991
|
1.14
|
|
16
|
Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression.
|
J Infect Dis
|
2001
|
1.01
|
|
17
|
A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation.
|
Development
|
1996
|
0.93
|
|
18
|
Blockage of skin invasion by schistosome cercariae by serine protease inhibitors.
|
Am J Trop Med Hyg
|
1999
|
0.90
|
|
19
|
Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines.
|
Eur J Cancer
|
1996
|
0.85
|
|
20
|
Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry.
|
J Pharm Biomed Anal
|
2012
|
0.83
|
|
21
|
Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin.
|
Int J Mol Sci
|
2012
|
0.83
|
|
22
|
Sustained suppression of plasma HIV RNA is associated with an increase in the production of mitogen-induced MIP-1alpha and MIP-1beta.
|
AIDS Res Hum Retroviruses
|
1999
|
0.83
|
|
23
|
Preparation of icariside II-phospholipid complex and its absorption across Caco-2 cell monolayers.
|
Pharmazie
|
2012
|
0.83
|
|
24
|
A nanostructured liquid crystalline formulation of 20(S)-protopanaxadiol with improved oral absorption.
|
Fitoterapia
|
2012
|
0.83
|
|
25
|
A novel drug-phospholipid complex loaded micelle for baohuoside I enhanced oral absorption: in vivo and in vivo evaluations.
|
Drug Dev Ind Pharm
|
2012
|
0.82
|
|
26
|
Effects of molybdate on steroid receptors in intact GH1 cells. Evidence for dissociation of an intracellular 10 S receptor oligomer prior to nuclear accumulation.
|
J Biol Chem
|
1985
|
0.82
|
|
27
|
Enhanced oral absorption of 20(S)-protopanaxadiol by self-assembled liquid crystalline nanoparticles containing piperine: in vitro and in vivo studies.
|
Int J Nanomedicine
|
2013
|
0.81
|
|
28
|
Combined treatment with Epimedium koreanum Nakai extract and gefitinib overcomes drug resistance caused by T790M mutation in non-small cell lung cancer cells.
|
Nutr Cancer
|
2014
|
0.80
|
|
29
|
[Study on preparation of icaritin by enzymolysis of icariin with snail hydrolase].
|
Zhongguo Zhong Yao Za Zhi
|
2010
|
0.79
|
|
30
|
Preparation of a nanoscale baohuoside I-phospholipid complex and determination of its absorption: in vivo and in vitro evaluations.
|
Int J Nanomedicine
|
2012
|
0.79
|
|
31
|
[Study on preparation of salvianolic acid phospholipid compound].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.79
|
|
32
|
Characterization of a recombinant Onchocerca volvulus antigen (Ov33) produced in yeast.
|
Am J Trop Med Hyg
|
1997
|
0.79
|
|
33
|
Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer.
|
Chem Biol Interact
|
2012
|
0.79
|
|
34
|
Enhancement of epimedium fried with suet oil based on in vivo formation of self-assembled flavonoid compound nanomicelles.
|
Molecules
|
2012
|
0.78
|
|
35
|
[Study on pharmacokinetics of 20 (S) -protopanaxadiol lipid cubic nanoparticles].
|
Zhongguo Zhong Yao Za Zhi
|
2013
|
0.78
|
|
36
|
Characterization of metabolites of 20(S)-protopanaxadiol in rats using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2013
|
0.78
|
|
37
|
Onchocerca volvulus: identification and characterization of an immunogenic eggshell protein (Oveg1).
|
Exp Parasitol
|
1995
|
0.78
|
|
38
|
Synthesis of dideoxy-pepstatin. Mechanism of inhibition of porcine pepsin.
|
Biochem Biophys Res Commun
|
1977
|
0.78
|
|
39
|
Child neck strength characteristics using an animal model.
|
Stapp Car Crash J
|
2000
|
0.78
|
|
40
|
FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival.
|
Transplant Proc
|
1998
|
0.77
|
|
41
|
[Preparation of baicalin colon-specific solid dispersion and evaluation on its in vitro release].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.77
|
|
42
|
Metabolic profiling of isomeric aglycones central-icaritin (c-IT) and icaritin (IT) in osteoporotic rats by UPLC-QTOF-MS.
|
Drug Test Anal
|
2014
|
0.77
|
|
43
|
[Comparative study on effect of crude and different processed products of epimedium on pharmacokinetics characteristics in mice].
|
Zhongguo Zhong Yao Za Zhi
|
2013
|
0.77
|
|
44
|
[Discussion on research ideas of synergistic mechanism of Epimedium fried with suet oil based on self-assembled micelles formation in vivo].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.76
|
|
45
|
Unrelated donor bone marrow transplantation for beta-thalassemia major: an experience from China.
|
Bone Marrow Transplant
|
2006
|
0.76
|
|
46
|
Metabolite profiles of epimedin C in rat plasma and bile by ultra-performance liquid chromatography coupled with quadrupole-TOF-MS.
|
Biomed Chromatogr
|
2014
|
0.76
|
|
47
|
Safety, tolerability, and antiretroviral effects of ritonavir-nelfinavir combination therapy administered for 48 weeks.
|
J Acquir Immune Defic Syndr
|
2000
|
0.76
|
|
48
|
The rabbit study: ritonavir and saquinavir in combination in saquinavir-experienced and previously untreated patients.
|
AIDS Res Hum Retroviruses
|
1999
|
0.76
|
|
49
|
β-cyclodextrin assistant flavonoid glycosides enzymatic hydrolysis.
|
Pharmacogn Mag
|
2013
|
0.76
|
|
50
|
[Processing mechanism of Epimedium fried with suet oil based on absorption and metabolism of flavonoids].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.76
|
|
51
|
Correction: Shuang, L.; et al. Autophagy Activated by Bluetongue Virus Infection Plays a Positive Role in Its Replication, Viruses 2015, 7, 4657-4675.
|
Viruses
|
2016
|
0.75
|
|
52
|
Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin.
|
J Nat Sci Biol Med
|
2013
|
0.75
|
|
53
|
The liver mediates apoptotic cell-induced immune regulation.
|
Scand J Immunol
|
2008
|
0.75
|
|
54
|
[Traditional Chinese medicine components and construction of components biopharmaceutical classification system].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
55
|
Hepatic schistosomiasis.
|
Prog Liver Dis
|
1994
|
0.75
|
|
56
|
[Content determination of epigoitrin in Radix Isatidis and its preparation by RP-HPLC].
|
Zhongguo Zhong Yao Za Zhi
|
2008
|
0.75
|
|
57
|
[Two-dimensional zebrafish model combined with hyphenated chromatographic techniques for evaluation anti-osteoporosis activity of epimendin A and its metabolite baohuoside I].
|
Yao Xue Xue Bao
|
2014
|
0.75
|
|
58
|
[Discussion about research progress and ideas on processing mechanism of traditional Chinese medicine].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
59
|
[Study on totai flavonoids of Epimedium assisted with soybean polysaccharide spray-drying powder].
|
Zhongguo Zhong Yao Za Zhi
|
2015
|
0.75
|
|
60
|
[Research on variation regularity of five main flavonoids contents in Epimedium and processed Epimedium].
|
Zhongguo Zhong Yao Za Zhi
|
2009
|
0.75
|
|
61
|
[Response surface method optimize of nano-silica solid dispersion technology assistant enzymatic hydrolysis preparation genistein].
|
Yao Xue Xue Bao
|
2012
|
0.75
|
|
62
|
[Discussion on correlation between preparation, in vivo conversion process and potential structure-activity relationship of ginsenoside].
|
Zhongguo Zhong Yao Za Zhi
|
2013
|
0.75
|
|
63
|
[Solidification of volatile oil with graphene oxide].
|
Yao Xue Xue Bao
|
2015
|
0.75
|
|
64
|
[Study on oral absorption enhancers of astragalus polysaccharides].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
65
|
[Effects of micronization on micromeritics properties of baicalin].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
66
|
[Studies on hydroxyapatite applicatied in coprecipitate of total salvianolic acids phospholipid complex].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
67
|
Metabolite profiles of epimedin B in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry.
|
J Agric Food Chem
|
2013
|
0.75
|
|
68
|
[Compared with colloidal silica and porous silica as baicalin solid dispersion carrier].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
69
|
[Polybasic research on the biopharmaceutical characteristics of 20 (S)-protopanaxadiol].
|
Yao Xue Xue Bao
|
2013
|
0.75
|
|
70
|
Influence of vitamin E tocopherol polyethylene glycol succinate 1000 on intestinal absorption of icariside II.
|
Pharmazie
|
2012
|
0.75
|
|
71
|
[Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
72
|
Metabolite profiling of four major flavonoids of Herba Epimedii in zebrafish.
|
Molecules
|
2012
|
0.75
|
|
73
|
[Ideas and methods of two-dimensional zebrafish model combined with chromatographic techniques in high-throughput screening of active anti-osteoporosis components of traditional Chinese medicines].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
74
|
[Effect of spray drying process on physical properties and dissolution of tanshinone].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
75
|
[Effect of suet oil on formation of self-assembled micelles of flavonoids in Epimedium].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
76
|
[Design technology of traditional Chinese medicine component and formulation].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
77
|
[Study on preparation of sagittatoside B with epimedin B converted from cellulase].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
78
|
[Study on preparation of CIT microemulsion and its absorption in intestine].
|
Zhongguo Zhong Yao Za Zhi
|
2010
|
0.75
|
|
79
|
[Construction of evaluation systems for traditional Chinese medicine multiple drug delivery system on basis of component level].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
80
|
[Preparation of naringenin by enzymolysis of naringin-HP-beta-CD].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
81
|
[Study on porous maize starch preparation and powdering coix seed oil].
|
Zhongguo Zhong Yao Za Zhi
|
2013
|
0.75
|
|
82
|
[Advance in studies on anti-cancer activity and mechanism of flavonoids].
|
Zhongguo Zhong Yao Za Zhi
|
2015
|
0.75
|
|
83
|
[Effect of dragon's blood powder with different grain size on transdermal absorption and adhesion of ZJHX paste].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
84
|
[Study on absorbing volatile oil with mesoporous carbon].
|
Zhongguo Zhong Yao Za Zhi
|
2014
|
0.75
|
|
85
|
Ex vivo inhibition of beta-thromboglobulin release following administration to man of ABT-299, a novel prodrug of a potent platelet activating factor antagonist.
|
Inflamm Res
|
1997
|
0.75
|
|
86
|
[Determination pharmacokinetics parameters of raw and different processed epimediums by pharmacology effect method].
|
Zhong Yao Cai
|
2013
|
0.75
|
|
87
|
[Study on sustained release preparations of Epimedium component].
|
Zhongguo Zhong Yao Za Zhi
|
2015
|
0.75
|
|
88
|
A review of the in vitro and in vivo neurochemical characterization of the NMDA/PCP/glycine/ion channel receptor macrocomplex.
|
Neurochem Res
|
1990
|
0.75
|
|
89
|
[Market investigation report on Epimedium material drugs and decoction pieces].
|
Zhongguo Zhong Yao Za Zhi
|
2010
|
0.75
|
|
90
|
[Study on porous starch as solid dispersion carrier of total Epimedium flavonoids].
|
Zhongguo Zhong Yao Za Zhi
|
2015
|
0.75
|
|
91
|
Genotyping of ABO blood group system by PCR and RFLP on mummies discovered at Taklamakan desert in 1912.
|
Nihon Hoigaku Zasshi
|
1996
|
0.75
|
|
92
|
[Construction of multiple drug release system based on components of traditional Chinese medicine].
|
Zhongguo Zhong Yao Za Zhi
|
2012
|
0.75
|
|
93
|
Ex vivo inhibition of PAF-induced beta-thromboglobulin release in man by ABT-299, a potent PAF antagonist.
|
Adv Exp Med Biol
|
1996
|
0.75
|