E Sun

Author PubWeight™ 130.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genome sequence of Drosophila melanogaster. Science 2000 74.32
2 Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group. Lancet 1998 4.54
3 ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results. AIDS 2001 3.35
4 Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir. Antimicrob Agents Chemother 1997 2.57
5 Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients. J Virol 2001 2.25
6 ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother 1998 2.23
7 The proteases and pathogenicity of parasitic protozoa. Annu Rev Microbiol 1993 1.96
8 Structure-based inhibitor design by using protein models for the development of antiparasitic agents. Proc Natl Acad Sci U S A 1993 1.82
9 Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteers. Antimicrob Agents Chemother 1998 1.60
10 Ritonavir and saquinavir combination therapy for the treatment of HIV infection. AIDS 1999 1.58
11 The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir. AIDS 1998 1.43
12 Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir. Clin Pharmacol Ther 1998 1.40
13 Recent developments in HIV protease inhibitor therapy. Antiviral Res 1998 1.33
14 Improvement in cell-mediated immune function during potent anti-human immunodeficiency virus therapy with ritonavir plus saquinavir. J Infect Dis 1998 1.18
15 Highly purified pea chloroplast RNA polymerase transcribes both rRNA and mRNA genes. Eur J Biochem 1991 1.14
16 Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression. J Infect Dis 2001 1.01
17 A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation. Development 1996 0.93
18 Blockage of skin invasion by schistosome cercariae by serine protease inhibitors. Am J Trop Med Hyg 1999 0.90
19 Capsaicin inhibits plasma membrane NADH oxidase and growth of human and mouse melanoma lines. Eur J Cancer 1996 0.85
20 Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry. J Pharm Biomed Anal 2012 0.83
21 Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin. Int J Mol Sci 2012 0.83
22 Sustained suppression of plasma HIV RNA is associated with an increase in the production of mitogen-induced MIP-1alpha and MIP-1beta. AIDS Res Hum Retroviruses 1999 0.83
23 Preparation of icariside II-phospholipid complex and its absorption across Caco-2 cell monolayers. Pharmazie 2012 0.83
24 A nanostructured liquid crystalline formulation of 20(S)-protopanaxadiol with improved oral absorption. Fitoterapia 2012 0.83
25 A novel drug-phospholipid complex loaded micelle for baohuoside I enhanced oral absorption: in vivo and in vivo evaluations. Drug Dev Ind Pharm 2012 0.82
26 Effects of molybdate on steroid receptors in intact GH1 cells. Evidence for dissociation of an intracellular 10 S receptor oligomer prior to nuclear accumulation. J Biol Chem 1985 0.82
27 Enhanced oral absorption of 20(S)-protopanaxadiol by self-assembled liquid crystalline nanoparticles containing piperine: in vitro and in vivo studies. Int J Nanomedicine 2013 0.81
28 Combined treatment with Epimedium koreanum Nakai extract and gefitinib overcomes drug resistance caused by T790M mutation in non-small cell lung cancer cells. Nutr Cancer 2014 0.80
29 [Study on preparation of icaritin by enzymolysis of icariin with snail hydrolase]. Zhongguo Zhong Yao Za Zhi 2010 0.79
30 Preparation of a nanoscale baohuoside I-phospholipid complex and determination of its absorption: in vivo and in vitro evaluations. Int J Nanomedicine 2012 0.79
31 [Study on preparation of salvianolic acid phospholipid compound]. Zhongguo Zhong Yao Za Zhi 2014 0.79
32 Characterization of a recombinant Onchocerca volvulus antigen (Ov33) produced in yeast. Am J Trop Med Hyg 1997 0.79
33 Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer. Chem Biol Interact 2012 0.79
34 Enhancement of epimedium fried with suet oil based on in vivo formation of self-assembled flavonoid compound nanomicelles. Molecules 2012 0.78
35 [Study on pharmacokinetics of 20 (S) -protopanaxadiol lipid cubic nanoparticles]. Zhongguo Zhong Yao Za Zhi 2013 0.78
36 Characterization of metabolites of 20(S)-protopanaxadiol in rats using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2013 0.78
37 Onchocerca volvulus: identification and characterization of an immunogenic eggshell protein (Oveg1). Exp Parasitol 1995 0.78
38 Synthesis of dideoxy-pepstatin. Mechanism of inhibition of porcine pepsin. Biochem Biophys Res Commun 1977 0.78
39 Child neck strength characteristics using an animal model. Stapp Car Crash J 2000 0.78
40 FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival. Transplant Proc 1998 0.77
41 [Preparation of baicalin colon-specific solid dispersion and evaluation on its in vitro release]. Zhongguo Zhong Yao Za Zhi 2014 0.77
42 Metabolic profiling of isomeric aglycones central-icaritin (c-IT) and icaritin (IT) in osteoporotic rats by UPLC-QTOF-MS. Drug Test Anal 2014 0.77
43 [Comparative study on effect of crude and different processed products of epimedium on pharmacokinetics characteristics in mice]. Zhongguo Zhong Yao Za Zhi 2013 0.77
44 [Discussion on research ideas of synergistic mechanism of Epimedium fried with suet oil based on self-assembled micelles formation in vivo]. Zhongguo Zhong Yao Za Zhi 2014 0.76
45 Unrelated donor bone marrow transplantation for beta-thalassemia major: an experience from China. Bone Marrow Transplant 2006 0.76
46 Metabolite profiles of epimedin C in rat plasma and bile by ultra-performance liquid chromatography coupled with quadrupole-TOF-MS. Biomed Chromatogr 2014 0.76
47 Safety, tolerability, and antiretroviral effects of ritonavir-nelfinavir combination therapy administered for 48 weeks. J Acquir Immune Defic Syndr 2000 0.76
48 The rabbit study: ritonavir and saquinavir in combination in saquinavir-experienced and previously untreated patients. AIDS Res Hum Retroviruses 1999 0.76
49 β-cyclodextrin assistant flavonoid glycosides enzymatic hydrolysis. Pharmacogn Mag 2013 0.76
50 [Processing mechanism of Epimedium fried with suet oil based on absorption and metabolism of flavonoids]. Zhongguo Zhong Yao Za Zhi 2014 0.76
51 Correction: Shuang, L.; et al. Autophagy Activated by Bluetongue Virus Infection Plays a Positive Role in Its Replication, Viruses 2015, 7, 4657-4675. Viruses 2016 0.75
52 Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin. J Nat Sci Biol Med 2013 0.75
53 The liver mediates apoptotic cell-induced immune regulation. Scand J Immunol 2008 0.75
54 [Traditional Chinese medicine components and construction of components biopharmaceutical classification system]. Zhongguo Zhong Yao Za Zhi 2012 0.75
55 Hepatic schistosomiasis. Prog Liver Dis 1994 0.75
56 [Content determination of epigoitrin in Radix Isatidis and its preparation by RP-HPLC]. Zhongguo Zhong Yao Za Zhi 2008 0.75
57 [Two-dimensional zebrafish model combined with hyphenated chromatographic techniques for evaluation anti-osteoporosis activity of epimendin A and its metabolite baohuoside I]. Yao Xue Xue Bao 2014 0.75
58 [Discussion about research progress and ideas on processing mechanism of traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi 2014 0.75
59 [Study on totai flavonoids of Epimedium assisted with soybean polysaccharide spray-drying powder]. Zhongguo Zhong Yao Za Zhi 2015 0.75
60 [Research on variation regularity of five main flavonoids contents in Epimedium and processed Epimedium]. Zhongguo Zhong Yao Za Zhi 2009 0.75
61 [Response surface method optimize of nano-silica solid dispersion technology assistant enzymatic hydrolysis preparation genistein]. Yao Xue Xue Bao 2012 0.75
62 [Discussion on correlation between preparation, in vivo conversion process and potential structure-activity relationship of ginsenoside]. Zhongguo Zhong Yao Za Zhi 2013 0.75
63 [Solidification of volatile oil with graphene oxide]. Yao Xue Xue Bao 2015 0.75
64 [Study on oral absorption enhancers of astragalus polysaccharides]. Zhongguo Zhong Yao Za Zhi 2014 0.75
65 [Effects of micronization on micromeritics properties of baicalin]. Zhongguo Zhong Yao Za Zhi 2014 0.75
66 [Studies on hydroxyapatite applicatied in coprecipitate of total salvianolic acids phospholipid complex]. Zhongguo Zhong Yao Za Zhi 2014 0.75
67 Metabolite profiles of epimedin B in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry. J Agric Food Chem 2013 0.75
68 [Compared with colloidal silica and porous silica as baicalin solid dispersion carrier]. Zhongguo Zhong Yao Za Zhi 2014 0.75
69 [Polybasic research on the biopharmaceutical characteristics of 20 (S)-protopanaxadiol]. Yao Xue Xue Bao 2013 0.75
70 Influence of vitamin E tocopherol polyethylene glycol succinate 1000 on intestinal absorption of icariside II. Pharmazie 2012 0.75
71 [Construction of research system for processing mechanism of traditional Chinese medicine based on chemical composition transformation combined with intestinal absorption barrier]. Zhongguo Zhong Yao Za Zhi 2014 0.75
72 Metabolite profiling of four major flavonoids of Herba Epimedii in zebrafish. Molecules 2012 0.75
73 [Ideas and methods of two-dimensional zebrafish model combined with chromatographic techniques in high-throughput screening of active anti-osteoporosis components of traditional Chinese medicines]. Zhongguo Zhong Yao Za Zhi 2014 0.75
74 [Effect of spray drying process on physical properties and dissolution of tanshinone]. Zhongguo Zhong Yao Za Zhi 2014 0.75
75 [Effect of suet oil on formation of self-assembled micelles of flavonoids in Epimedium]. Zhongguo Zhong Yao Za Zhi 2014 0.75
76 [Design technology of traditional Chinese medicine component and formulation]. Zhongguo Zhong Yao Za Zhi 2012 0.75
77 [Study on preparation of sagittatoside B with epimedin B converted from cellulase]. Zhongguo Zhong Yao Za Zhi 2014 0.75
78 [Study on preparation of CIT microemulsion and its absorption in intestine]. Zhongguo Zhong Yao Za Zhi 2010 0.75
79 [Construction of evaluation systems for traditional Chinese medicine multiple drug delivery system on basis of component level]. Zhongguo Zhong Yao Za Zhi 2012 0.75
80 [Preparation of naringenin by enzymolysis of naringin-HP-beta-CD]. Zhongguo Zhong Yao Za Zhi 2012 0.75
81 [Study on porous maize starch preparation and powdering coix seed oil]. Zhongguo Zhong Yao Za Zhi 2013 0.75
82 [Advance in studies on anti-cancer activity and mechanism of flavonoids]. Zhongguo Zhong Yao Za Zhi 2015 0.75
83 [Effect of dragon's blood powder with different grain size on transdermal absorption and adhesion of ZJHX paste]. Zhongguo Zhong Yao Za Zhi 2012 0.75
84 [Study on absorbing volatile oil with mesoporous carbon]. Zhongguo Zhong Yao Za Zhi 2014 0.75
85 Ex vivo inhibition of beta-thromboglobulin release following administration to man of ABT-299, a novel prodrug of a potent platelet activating factor antagonist. Inflamm Res 1997 0.75
86 [Determination pharmacokinetics parameters of raw and different processed epimediums by pharmacology effect method]. Zhong Yao Cai 2013 0.75
87 [Study on sustained release preparations of Epimedium component]. Zhongguo Zhong Yao Za Zhi 2015 0.75
88 A review of the in vitro and in vivo neurochemical characterization of the NMDA/PCP/glycine/ion channel receptor macrocomplex. Neurochem Res 1990 0.75
89 [Market investigation report on Epimedium material drugs and decoction pieces]. Zhongguo Zhong Yao Za Zhi 2010 0.75
90 [Study on porous starch as solid dispersion carrier of total Epimedium flavonoids]. Zhongguo Zhong Yao Za Zhi 2015 0.75
91 Genotyping of ABO blood group system by PCR and RFLP on mummies discovered at Taklamakan desert in 1912. Nihon Hoigaku Zasshi 1996 0.75
92 [Construction of multiple drug release system based on components of traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi 2012 0.75
93 Ex vivo inhibition of PAF-induced beta-thromboglobulin release in man by ABT-299, a potent PAF antagonist. Adv Exp Med Biol 1996 0.75