Published in Am J Pathol on July 01, 2014
Renal protective effect of sirtuin 1. J Diabetes Res (2014) 1.05
Nephrin Preserves Podocyte Viability and Glomerular Structure and Function in Adult Kidneys. J Am Soc Nephrol (2015) 0.90
Reduction in podocyte SIRT1 accelerates kidney injury in aging mice. Am J Physiol Renal Physiol (2017) 0.75
Retinoic acid improves nephrotoxic serum-induced glomerulonephritis through activation of podocyte retinoic acid receptor α. Kidney Int (2017) 0.75
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature (2005) 18.41
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol (2008) 17.81
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (2004) 17.38
Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell (2001) 15.05
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J (2008) 12.89
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature (2004) 10.32
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. BMC Bioinformatics (2012) 8.61
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J (2002) 6.37
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J Biol Chem (2005) 5.93
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol (2005) 5.54
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice. Cell Metab (2005) 5.39
SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell (2007) 5.01
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proc Natl Acad Sci U S A (2007) 4.87
A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol (2002) 4.63
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc (2009) 4.47
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem (2008) 4.16
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci U S A (2006) 4.07
A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell (2011) 3.69
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest (2010) 3.44
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J Biol Chem (2004) 3.39
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab (2005) 3.15
Podocyte-specific expression of cre recombinase in transgenic mice. Genesis (2003) 3.11
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest (2010) 2.92
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim Biophys Acta (2010) 2.70
Transcriptional integration of mitochondrial biogenesis. Trends Endocrinol Metab (2012) 2.34
Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes. Nat Med (2013) 2.29
A simplified method for HPLC determination of creatinine in mouse serum. Am J Physiol Renal Physiol (2004) 2.17
An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice. Nat Med (2008) 2.12
Integration of cellular bioenergetics with mitochondrial quality control and autophagy. Biol Chem (2012) 2.08
Sirt1 activation protects the mouse renal medulla from oxidative injury. J Clin Invest (2010) 1.90
Inducible podocyte-specific gene expression in transgenic mice. J Am Soc Nephrol (2003) 1.87
Adriamycin nephropathy: a model of focal segmental glomerulosclerosis. Nephrology (Carlton) (2011) 1.82
Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxid Redox Signal (2011) 1.79
PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders. J Cell Sci (2012) 1.73
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab (2012) 1.66
Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway. Diabetes (2011) 1.61
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int (2013) 1.55
Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function. J Biol Chem (2010) 1.45
Sirtuins at a glance. J Cell Sci (2011) 1.41
Adriamycin alters glomerular endothelium to induce proteinuria. J Am Soc Nephrol (2008) 1.38
Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice. J Clin Invest (2010) 1.34
SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice. Breast Cancer Res (2007) 1.30
SIRT1: regulation of longevity via autophagy. Cell Signal (2009) 1.29
Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus. PLoS One (2011) 1.24
Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition. Int J Biol Sci (2010) 1.16
Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in diabetic Wistar fatty (fa/fa) rats: a model of type 2 diabetes. Exp Diabetes Res (2011) 1.14
Streptozotocin-induced diabetic models in mice and rats. Curr Protoc Pharmacol (2008) 1.12
Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy. Free Radic Res (2008) 1.04
Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis (2010) 1.01
Expression of HIV transgene aggravates kidney injury in diabetic mice. Kidney Int (2013) 1.00
Podocyte cell-specific expression of doxycycline inducible Cre recombinase in mice. J Am Soc Nephrol (2006) 0.91
Deciphering the renal code: advances in conditional gene targeting. Physiology (Bethesda) (2004) 0.90
Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy. AIDS (2013) 0.88
Progress in gene targeting: using mutant mice to study renal function and disease. Kidney Int (2008) 0.87
Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2. Kidney Int (2010) 0.85