Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts.

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🔗 View Article (PMC 4154988)

Published in Clin Cancer Res on July 10, 2014

Authors

Santi Suryani1, Hernan Carol1, Triona Ni Chonghaile2, Viktoras Frismantas3, Chintanu Sarmah1, Laura High1, Beat Bornhauser3, Mark J Cowley4, Barbara Szymanska1, Kathryn Evans1, Ingrid Boehm1, Elise Tonna1, Luke Jones1, Donya Moradi Manesh1, Raushan T Kurmasheva5, Catherine Billups6, Warren Kaplan4, Anthony Letai2, Jean-Pierre Bourquin3, Peter J Houghton5, Malcolm A Smith7, Richard B Lock8

Author Affiliations

1: Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW, Sydney, Australia.
2: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
3: Division of Pediatric Oncology, University Children's Hospital, Zurich, Switzerland.
4: Peter Wills Bioinformatics Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.
5: Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio.
6: Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee.
7: Cancer Therapy Evaluation Program, NCI, Bethesda, Maryland.
8: Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW, Sydney, Australia. rlock@ccia.unsw.edu.au.

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