Published in J Phys Chem A on July 31, 2014
Fluorescence quenching studies of structure and dynamics in calmodulin-eNOS complexes. FEBS Lett (2015) 0.81
Insight into structural rearrangements and interdomain interactions related to electron transfer between flavin mononucleotide and heme in nitric oxide synthase: A molecular dynamics study. J Inorg Biochem (2015) 0.76
Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap. ACS Catal (2016) 0.76
A perspective on conformational control of electron transfer in nitric oxide synthases. Nitric Oxide (2016) 0.75
Elucidating nitric oxide synthase domain interactions by molecular dynamics. Protein Sci (2015) 0.75
Restricting the conformational freedom of the neuronal nitric-oxide synthase flavoprotein domain reveals impact on electron transfer and catalysis. J Biol Chem (2017) 0.75
Solving Kinetic Equations for the Laser Flash Photolysis Experiment on Nitric Oxide Synthases: Effect of Conformational Dynamics on the Interdomain Electron Transfer. J Phys Chem A (2015) 0.75
Nitric oxide synthases: structure, function and inhibition. Biochem J (2001) 9.73
Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell (1998) 3.20
Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes. Proc Natl Acad Sci U S A (1997) 3.15
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science (1998) 2.75
Structure of a cytochrome P450-redox partner electron-transfer complex. Proc Natl Acad Sci U S A (1999) 2.30
Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase. J Biol Chem (2004) 2.28
P450 BM3: the very model of a modern flavocytochrome. Trends Biochem Sci (2002) 1.77
The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis. Biochemistry (2002) 1.65
Intrinsic and extrinsic modulation of nitric oxide synthase activity. Chem Rev (2002) 1.51
Pulsed EPR determination of the distance between heme iron and FMN centers in a human inducible nitric oxide synthase. J Am Chem Soc (2010) 1.45
Crystal structure of the FAD/NADPH-binding domain of rat neuronal nitric-oxide synthase. Comparisons with NADPH-cytochrome P450 oxidoreductase. J Biol Chem (2001) 1.39
Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain. FEBS J (2009) 1.39
Optical difference spectrophotometry as a probe of rat brain nitric oxide synthase heme-substrate interaction. Biochemistry (1993) 1.38
Structural basis for endothelial nitric oxide synthase binding to calmodulin. EMBO J (2003) 1.37
A connecting hinge represses the activity of endothelial nitric oxide synthase. Proc Natl Acad Sci U S A (2007) 1.32
NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J Biol Chem (2001) 1.31
Structural studies of constitutive nitric oxide synthases with diatomic ligands bound. J Biol Inorg Chem (2006) 1.28
Direct measurement by laser flash photolysis of intraprotein electron transfer in a rat neuronal nitric oxide synthase. J Am Chem Soc (2007) 1.26
Regulation of interdomain interactions by calmodulin in inducible nitric-oxide synthase. J Biol Chem (2009) 1.25
Intraprotein electron transfer in a two-domain construct of neuronal nitric oxide synthase: the output state in nitric oxide formation. Biochemistry (2006) 1.25
Nitric oxide synthases: domain structure and alignment in enzyme function and control. Front Biosci (2003) 1.24
Effect of freezing conditions on distances and their distributions derived from Double Electron Electron Resonance (DEER): a study of doubly-spin-labeled T4 lysozyme. J Magn Reson (2012) 1.22
Nitric-oxide synthase output state. Design and properties of nitric-oxide synthase oxygenase/FMN domain constructs. J Biol Chem (2006) 1.22
Regulation of FMN subdomain interactions and function in neuronal nitric oxide synthase. Biochemistry (2009) 1.22
Direct measurement by laser flash photolysis of intramolecular electron transfer in a two-domain construct of murine inducible nitric oxide synthase. J Am Chem Soc (2006) 1.18
Differential binding of calmodulin domains to constitutive and inducible nitric oxide synthase enzymes. Biochemistry (2007) 1.16
Importance of the domain-domain interface to the catalytic action of the NO synthase reductase domain. Biochemistry (2008) 1.13
Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of HIV-1 reverse transcriptase revealed by site-directed spin labelling. J Mol Biol (2000) 1.09
Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme. J Biol Inorg Chem (2008) 1.09
Differential activation of nitric-oxide synthase isozymes by calmodulin-troponin C chimeras. J Biol Chem (2004) 1.07
Regulation of interdomain electron transfer in the NOS output state for NO production. Dalton Trans (2009) 1.01
FMN fluorescence in inducible NOS constructs reveals a series of conformational states involved in the reductase catalytic cycle. FEBS J (2012) 1.00
Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation. Proc Natl Acad Sci U S A (2013) 1.00
Calmodulin-induced structural changes in endothelial nitric oxide synthase. FEBS Lett (2012) 0.98
Surface charges and regulation of FMN to heme electron transfer in nitric-oxide synthase. J Biol Chem (2010) 0.97
Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions. Coord Chem Rev (2011) 0.97
Calmodulin activates neuronal nitric oxide synthase by enabling transitions between conformational states. FEBS Lett (2012) 0.96
Phosphorylation within an autoinhibitory domain in endothelial nitric oxide synthase reduces the Ca(2+) concentrations required for calmodulin to bind and activate the enzyme. Biochemistry (2008) 0.96
Effect of solution viscosity on intraprotein electron transfer between the FMN and heme domains in inducible nitric oxide synthase. FEBS Lett (2011) 0.92
Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain. J Biol Chem (2014) 0.92
Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin binding, increase FMN shielding, and suppress interflavin electron transfer. J Biol Chem (2009) 0.89
Crucial role of Lys(423) in the electron transfer of neuronal nitric-oxide synthase. J Biol Chem (1999) 0.89
Energy landscapes and catalysis in nitric-oxide synthase. J Biol Chem (2014) 0.87
Electron dipole-dipole ESEEM in field-step ELDOR of nitroxide biradicals. J Magn Reson (2002) 0.85
Dissecting regulation mechanism of the FMN to heme interdomain electron transfer in nitric oxide synthases. J Inorg Biochem (2013) 0.84
Regulatory role of Glu546 in flavin mononucleotide-heme electron transfer in human inducible nitric oxide synthase. Inorg Chem (2013) 0.83
FRET conformational analysis of calmodulin binding to nitric oxide synthase peptides and enzymes. Biochemistry (2008) 0.79
Genome-wide atlas of gene expression in the adult mouse brain. Nature (2006) 28.02
Prevalence of diabetes among men and women in China. N Engl J Med (2010) 19.98
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature (2012) 15.91
The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol (2007) 13.99
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
The Protein Data Bank and structural genomics. Nucleic Acids Res (2003) 8.34
The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema. Nucleic Acids Res (2005) 7.81
The distribution and query systems of the RCSB Protein Data Bank. Nucleic Acids Res (2004) 7.03
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med (2009) 6.61
The RCSB PDB information portal for structural genomics. Nucleic Acids Res (2006) 6.36
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A (2006) 5.16
An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol (2009) 4.62
Tools for the automatic identification and classification of RNA base pairs. Nucleic Acids Res (2003) 4.12
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome. Genome Res (2010) 3.34
Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J Invest Dermatol (2013) 3.32
Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature (2011) 3.19
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
Gene dosage of the common variant 9p21 predicts severity of coronary artery disease. J Am Coll Cardiol (2010) 3.07
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy. Nat Biotechnol (2012) 2.98
Potential clinical and economic consequences of noncardiac incidental findings on cardiac computed tomography. J Am Coll Cardiol (2009) 2.76
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. Cancer Discov (2014) 2.64
Ambient air pollution, birth weight and preterm birth: a systematic review and meta-analysis. Environ Res (2012) 2.63
TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med (2005) 2.62
Darbepoetin alpha for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol (2008) 2.60
Prevalence of cardiovascular disease risk factor in the Chinese population: the 2007-2008 China National Diabetes and Metabolic Disorders Study. Eur Heart J (2011) 2.57
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50
Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns. Proc Natl Acad Sci U S A (2014) 2.42
Prognostic value of 64-slice cardiac computed tomography severity of coronary artery disease, coronary atherosclerosis, and left ventricular ejection fraction. J Am Coll Cardiol (2010) 2.21
Ligand Depot: a data warehouse for ligands bound to macromolecules. Bioinformatics (2004) 2.21
Diagnostic accuracy and impact of computed tomographic coronary angiography on utilization of invasive coronary angiography. Circ Cardiovasc Imaging (2009) 2.16
Molecular evidence of persistent epidemic and evolution of subgenotype B1 coxsackievirus A16-associated hand, foot, and mouth disease in China. J Clin Microbiol (2009) 2.11
Prognostic value of CT angiography in coronary bypass patients. JACC Cardiovasc Imaging (2011) 2.10
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res (2009) 2.08
Oxidative mechanism of arsenic toxicity and carcinogenesis. Mol Cell Biochem (2004) 2.07
Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis. Gastroenterology (2008) 1.99
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci Transl Med (2012) 1.99
The locus of fixation and the foveal cone mosaic. J Vis (2005) 1.96
Prevalence of ideal cardiovascular health and its relationship with the 4-year cardiovascular events in a northern Chinese industrial city. Circ Cardiovasc Qual Outcomes (2012) 1.93
Normobaric hyperoxia reduces the neurovascular complications associated with delayed tissue plasminogen activator treatment in a rat model of focal cerebral ischemia. Stroke (2009) 1.90
Function, structure, and evolution of the RubisCO-like proteins and their RubisCO homologs. Microbiol Mol Biol Rev (2007) 1.89
Incremental prognostic value of cardiac computed tomography in coronary artery disease using CONFIRM: COroNary computed tomography angiography evaluation for clinical outcomes: an InteRnational Multicenter registry. Circ Cardiovasc Imaging (2011) 1.89
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol (2004) 1.85
Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect (2008) 1.83
Bipolar resistance switching characteristics with opposite polarity of Au/SrTiO3/Ti memory cells. Nanoscale Res Lett (2011) 1.82
Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci. PLoS Genet (2013) 1.81
Questionable value of planting thirsty trees in dry regions. Nature (2010) 1.81
Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam. Implications for the dioxygen activation mechanism. J Biol Chem (2005) 1.77
Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A. Mol Cell Biol (2005) 1.74
Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science (2003) 1.73
An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer. Nucleic Acids Res (2010) 1.73
Can differences in corrected coronary opacification measured with computed tomography predict resting coronary artery flow? J Am Coll Cardiol (2011) 1.70
Heart valve prosthesis selection in patients with end-stage renal disease requiring dialysis: a systematic review and meta-analysis. Heart (2011) 1.70
Structure-function studies on nitric oxide synthases. J Inorg Biochem (2005) 1.69
Disharmony between society and environmental carrying capacity: a historical review, with an emphasis on China. Ambio (2007) 1.68
A novel superhydrophilic and underwater superoleophobic hydrogel-coated mesh for oil/water separation. Adv Mater (2011) 1.67
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res (2010) 1.67
The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis. Biochemistry (2002) 1.65
Type 2 vaccine-derived poliovirus from patients with acute flaccid paralysis in china: current immunization strategy effectively prevented its sustained transmission. J Infect Dis (2010) 1.65
Kinesin family member 6 variant Trp719Arg does not associate with angiographically defined coronary artery disease in the Ottawa Heart Genomics Study. J Am Coll Cardiol (2009) 1.64
Resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction. Cardiovasc Drugs Ther (2008) 1.63
Smartphone versus pen-and-paper data collection of infant feeding practices in rural China. J Med Internet Res (2012) 1.62
Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome. J Am Coll Cardiol (2012) 1.61
Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab (2004) 1.60
The PP2A inhibitor SET regulates granzyme B expression in human natural killer cells. Blood (2010) 1.60
Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants. Free Radic Biol Med (2007) 1.59
Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy. Ann Neurol (2009) 1.58
Outdoor air pollution and emergency department visits for asthma among children and adults: a case-crossover study in northern Alberta, Canada. Environ Health (2007) 1.55
Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia. J Cereb Blood Flow Metab (2006) 1.54
Network meta-analysis of prasugrel, ticagrelor, high- and standard-dose clopidogrel in patients scheduled for percutaneous coronary interventions. Thromb Haemost (2012) 1.54
Neural compensation for the eye's optical aberrations. J Vis (2004) 1.53
The effects of continuous positive airway pressure on myocardial energetics in patients with heart failure and obstructive sleep apnea. J Am Coll Cardiol (2007) 1.53
Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia. J Neurochem (2009) 1.53
What is the prognostic value of myocardial perfusion imaging using rubidium-82 positron emission tomography? J Am Coll Cardiol (2006) 1.52
Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality. Circulation (2012) 1.52
Global functional analyses of cellular responses to pore-forming toxins. PLoS Pathog (2011) 1.52
Associations between outdoor air pollution and emergency department visits for stroke in Edmonton, Canada. Eur J Epidemiol (2006) 1.51
Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease. J Clin Invest (2015) 1.51
Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies. BMJ (2013) 1.50
hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation. Mol Cell Biol (2005) 1.50
Comparison of premier CAMPY enzyme immunoassay (EIA), ProSpecT Campylobacter EIA, and ImmunoCard STAT! CAMPY tests with culture for laboratory diagnosis of Campylobacter enteric infections. J Clin Microbiol (2010) 1.49
Posttranscriptional control of the competence factor betaFTZ-F1 by juvenile hormone in the mosquito Aedes aegypti. Proc Natl Acad Sci U S A (2003) 1.49
miR-155 regulates IFN-γ production in natural killer cells. Blood (2012) 1.47
Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors. J Am Chem Soc (2008) 1.47
Discordance between Framingham Risk Score and atherosclerotic plaque burden. Eur Heart J (2013) 1.46
Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Proc Natl Acad Sci U S A (2007) 1.46
Mutation analysis of PEX7 in 60 probands with rhizomelic chondrodysplasia punctata and functional correlations of genotype with phenotype. Hum Mutat (2002) 1.45
Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs. J Biol Chem (2011) 1.45
ERβ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. Cancer Biol Ther (2011) 1.45
Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J Am Chem Soc (2010) 1.45