Published in BMC Med Genomics on August 09, 2014
Upregulation of long noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor prognosis in hepatocellular carcinoma. Oncogene (2015) 1.14
Anticancer Cytokines: Biology and Clinical Effects of Interferon-α2, Interleukin (IL)-2, IL-15, IL-21, and IL-12. Semin Oncol (2015) 0.89
Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet. BMC Genomics (2015) 0.84
Meta-analysis of chemotherapy and dendritic cells with cytokine-induced killer cells in the treatment of non-small-cell lung cancer. Int J Clin Exp Med (2015) 0.82
Matrine regulates immune functions to inhibit the proliferation of leukemic cells. Int J Clin Exp Med (2015) 0.79
MicroRNA profiling of CD3+ CD56+ cytokine-induced killer cells. Sci Rep (2015) 0.75
MiR-9a-5p regulates proliferation and migration of hepatic stellate cells under pressure through inhibition of Sirt1. World J Gastroenterol (2015) 0.75
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00
Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res (2003) 103.76
Differential expression analysis for sequence count data. Genome Biol (2010) 64.56
The KEGG resource for deciphering the genome. Nucleic Acids Res (2004) 53.05
Network biology: understanding the cell's functional organization. Nat Rev Genet (2004) 36.62
Hierarchical organization of modularity in metabolic networks. Science (2002) 22.47
Reactome: a knowledgebase of biological pathways. Nucleic Acids Res (2005) 20.05
Wnt signalling in stem cells and cancer. Nature (2005) 19.26
The Gene Ontology (GO) project in 2006. Nucleic Acids Res (2006) 13.79
MapSplice: accurate mapping of RNA-seq reads for splice junction discovery. Nucleic Acids Res (2010) 9.80
A systems biology approach for pathway level analysis. Genome Res (2007) 6.95
Network-constrained regularization and variable selection for analysis of genomic data. Bioinformatics (2008) 6.01
Relating whole-genome expression data with protein-protein interactions. Genome Res (2002) 5.78
Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp Med (1994) 5.20
Interleukin 15: biology and relevance to human disease. Blood (2001) 4.47
RSeQC: quality control of RNA-seq experiments. Bioinformatics (2012) 4.31
False discovery rate, sensitivity and sample size for microarray studies. Bioinformatics (2005) 3.83
CTLA-4-Mediated inhibition of early events of T cell proliferation. J Immunol (1999) 3.49
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity (2001) 3.45
Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med (2002) 3.20
Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J Exp Med (1991) 3.03
A Markov random field model for network-based analysis of genomic data. Bioinformatics (2007) 2.93
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat Med (2012) 2.66
KEGGgraph: a graph approach to KEGG PATHWAY in R and bioconductor. Bioinformatics (2009) 2.31
Phase I study of recombinant human CD40 ligand in cancer patients. J Clin Oncol (2001) 2.12
Human gene coexpression landscape: confident network derived from tissue transcriptomic profiles. PLoS One (2008) 2.09
WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data. BMC Bioinformatics (2006) 1.95
Prospect of targeting the CD40 pathway for cancer therapy. Clin Cancer Res (2007) 1.75
PDGF-D is a potent transforming and angiogenic growth factor. Oncogene (2003) 1.63
Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. Cancer Res (2007) 1.56
Emerging roles of PDGF-D signaling pathway in tumor development and progression. Biochim Biophys Acta (2010) 1.42
CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol Cell Biol (2000) 1.35
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat Immunol (2012) 1.34
Wnt4/β-catenin signaling induces VSMC proliferation and is associated with intimal thickening. Circ Res (2010) 1.24
Cytokine-induced killer cells promote antitumor immunity. J Transl Med (2013) 1.16
Cytokine-induced NK-like T cells: from bench to bedside. J Biomed Biotechnol (2010) 1.13
Retracted Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-κB signaling pathways. Breast Cancer Res Treat (2010) 1.08
The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells. Cytotherapy (2011) 1.04
Evaluation of gene association methods for coexpression network construction and biological knowledge discovery. PLoS One (2012) 1.04
PDGF-D signaling: a novel target in cancer therapy. Curr Drug Targets (2009) 1.04
Characterization of interleukin-15 gene-modified human natural killer cells: implications for adoptive cellular immunotherapy. Haematologica (2004) 0.99
AACR Cancer Progress Report 2013. Clin Cancer Res (2013) 0.95
IFNβ produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response. Cancer Res (2011) 0.93
Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model. PLoS One (2012) 0.90
WNT4 and RSPO1 together are required for cell proliferation in the early mouse gonad. Development (2012) 0.86
The structure of a gene co-expression network reveals biological functions underlying eQTLs. PLoS One (2013) 0.86
LegumeGRN: a gene regulatory network prediction server for functional and comparative studies. PLoS One (2013) 0.86
Effects of MICA expression on the prognosis of advanced non-small cell lung cancer and the efficacy of CIK therapy. PLoS One (2013) 0.84
CD40 stimulates a "feed-forward" NF-κB-driven molecular pathway that regulates IFN-β expression in carcinoma cells. J Immunol (2012) 0.81
The CIK cells stimulated with combination of IL-2 and IL-15 provide an improved cytotoxic capacity against human lung adenocarcinoma. Tumour Biol (2013) 0.78
The chromosomal basis of cancer. Cell Oncol (2005) 3.63
Meta-analysis suggests that smoking is associated with an increased risk of early natural menopause. Menopause (2012) 2.36
NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy. Arterioscler Thromb Vasc Biol (2003) 2.30
Human papillomavirus infection and increased risk of HIV acquisition. A systematic review and meta-analysis. AIDS (2012) 2.15
Potential bridges for HIV infection to men who have sex with men in Guangzhou, China. AIDS Behav (2006) 2.06
Accumulation of advanced oxidation protein products induces podocyte apoptosis and deletion through NADPH-dependent mechanisms. Kidney Int (2009) 1.84
Repeat-region polymorphisms in the gene for the dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related molecule: effects on HIV-1 susceptibility. J Infect Dis (2006) 1.62
Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing. Proc Natl Acad Sci U S A (2011) 1.60
The coexistence of superconductivity and topological order in the Bi₂Se₃ thin films. Science (2012) 1.56
Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. J Neurosci (2009) 1.54
In vivo bone regeneration using tubular perfusion system bioreactor cultured nanofibrous scaffolds. Tissue Eng Part A (2013) 1.53
Glutamate metabolism in major depressive disorder. Am J Psychiatry (2014) 1.52
Multistep carcinogenesis: a chain reaction of aneuploidizations. Cell Cycle (2003) 1.49
Specific clones of spontaneously evolving karyotypes generate individuality of cancers. Cancer Genet Cytogenet (2008) 1.48
Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population. Rheumatol Int (2012) 1.45
Imaging features of small intestinal amyloidosis: a case report. Abdom Imaging (2011) 1.43
Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet (2010) 1.42
Temporal changes in matrix metalloproteinase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice. Life Sci (2004) 1.40
Response to the Center for Medicare & Medicaid Services coverage with evidence development request for primary prevention implantable cardioverter-defibrillators: data from the OMNI study. Heart Rhythm (2012) 1.40
IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation. Cancer Res (2009) 1.39
OsC6, encoding a lipid transfer protein, is required for postmeiotic anther development in rice. Plant Physiol (2010) 1.39
Efficacy of human papillomavirus-based screen-and-treat for cervical cancer prevention among HIV-infected women. AIDS (2010) 1.36
Aneuploidy and cancer: from correlation to causation. Contrib Microbiol (2006) 1.35
C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection. Proc Natl Acad Sci U S A (2011) 1.31
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus. PLoS One (2010) 1.30
PERSISTENT TAPETAL CELL1 encodes a PHD-finger protein that is required for tapetal cell death and pollen development in rice. Plant Physiol (2011) 1.28
Rice MADS3 regulates ROS homeostasis during late anther development. Plant Cell (2011) 1.28
Genetic framework of cyclin-dependent kinase function in Arabidopsis. Dev Cell (2012) 1.26
Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PLoS One (2009) 1.26
IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection. J Immunol (2010) 1.25
Dielectrophoretic separation of colorectal cancer cells. Biomicrofluidics (2010) 1.25
Does blood glucose monitoring increase prior to clinic visits in children with type 1 diabetes? Diabetes Care (2011) 1.22
Endogenous interleukin-4 promotes tumor development by increasing tumor cell resistance to apoptosis. Cancer Res (2008) 1.21
Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. J Clin Invest (2013) 1.20
Bioactive electrospun scaffolds delivering growth factors and genes for tissue engineering applications. Pharm Res (2010) 1.18
Contact-free Measurement of Heart Rate Variability via a Microwave Sensor. Sensors (Basel) (2009) 1.18
Population normative data for the 10/66 Dementia Research Group cognitive test battery from Latin America, India and China: a cross-sectional survey. BMC Neurol (2009) 1.18
grassy tillers1 promotes apical dominance in maize and responds to shade signals in the grasses. Proc Natl Acad Sci U S A (2011) 1.18
Cancer drug resistance: the central role of the karyotype. Drug Resist Updat (2007) 1.17
Activation of microglia and chemokines in light-induced retinal degeneration. Mol Vis (2005) 1.16
Polymer-coated nanoparticles: a universal tool for biolabelling experiments. Small (2011) 1.16
Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat. PLoS One (2010) 1.14
Structure-based discovery of natural-product-like TNF-α inhibitors. Angew Chem Int Ed Engl (2010) 1.13
Quantification of the relative roles of niche and neutral processes in structuring gastrointestinal microbiomes. Proc Natl Acad Sci U S A (2012) 1.10
Role of AT2 receptors in the cardioprotective effect of AT1 antagonists in mice. Hypertension (2002) 1.10
ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. Am J Med Genet B Neuropsychiatr Genet (2013) 1.08
Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase. Endocrinology (2008) 1.08
Viral load in the natural history of human papillomavirus type 16 infection: a nested case-control study. J Infect Dis (2011) 1.08
Electrophilic carbocyclization of aryl propargylic alcohols: a facile synthesis of diiodinated carbocycles and heterocycles. Org Lett (2011) 1.08
Biomaterials and scaffolds for ligament tissue engineering. J Biomed Mater Res A (2006) 1.07
In vitro study of human vascular endothelial cell function on materials with various surface roughness. J Biomed Mater Res A (2004) 1.06
The AGL6-like gene OsMADS6 regulates floral organ and meristem identities in rice. Cell Res (2009) 1.06
Preliminary characterization of the oral microbiota of Chinese adults with and without gingivitis. BMC Oral Health (2011) 1.05
Accessing men who have sex with men through long-chain referral recruitment, Guangzhou, China. AIDS Behav (2008) 1.05
Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla. Biol Psychiatry (2011) 1.04
Parent-adolescent interaction and risk of adolescent internet addiction: a population-based study in Shanghai. BMC Psychiatry (2014) 1.04
Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation. Nucleic Acids Res (2014) 1.04
The performance of dental pulp stem cells on nanofibrous PCL/gelatin/nHA scaffolds. J Biomed Mater Res A (2010) 1.04
Genome-wide analysis of WOX gene family in rice, sorghum, maize, Arabidopsis and poplar. J Integr Plant Biol (2010) 1.04
Sr(1.7)Zn(0.3)CeO4: Eu3+ novel red-emitting phosphors: synthesis and photoluminescence properties. ACS Appl Mater Interfaces (2014) 1.03
Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. J Biol Chem (2008) 1.03
Neuroprotection of photoreceptors by minocycline in light-induced retinal degeneration. Invest Ophthalmol Vis Sci (2004) 1.02
Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci (2008) 1.02
Concentration-dependent effects on intracellular and surface pH of exposing Xenopus oocytes to solutions containing NH3/NH4(+). J Membr Biol (2009) 1.02
Regulation of male fertility by X-linked genes. J Androl (2009) 1.01
A novel onco-miR-365 induces cutaneous squamous cell carcinoma. Carcinogenesis (2013) 1.01
Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection. Eur J Immunol (2009) 1.01
In vivo bone generation via the endochondral pathway on three-dimensional electrospun fibers. Acta Biomater (2012) 1.00
Highly efficient high-power thulium-doped germanate glass fiber laser. Opt Lett (2007) 1.00
Diagnostic accuracy of contrast-enhanced ultrasound for renal cell carcinoma: a meta-analysis. Tumour Biol (2014) 0.99
Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation. Phytomedicine (2011) 0.98
Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3β signaling. Neurochem Int (2011) 0.98
Regulatory modules controlling maize inflorescence architecture. Genome Res (2013) 0.97
Adeno-associated virus (AAV)-mediated transduction of male germ line stem cells results in transgene transmission after germ cell transplantation. FASEB J (2007) 0.96
Biocompatibility and degradation characteristics of PLGA-based electrospun nanofibrous scaffolds with nanoapatite incorporation. Biomaterials (2012) 0.96
Effect of ACE inhibitors and angiotensin II type 1 receptor antagonists on endothelial NO synthase knockout mice with heart failure. Hypertension (2002) 0.96
Coculture of osteoblasts and endothelial cells: optimization of culture medium and cell ratio. Tissue Eng Part C Methods (2010) 0.96
Prevalence of hypertension in China: a systematic review and meta-regression analysis of trends and regional differences. J Hypertens (2014) 0.96
Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine. J Neurochem (2010) 0.95
Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites. J Bone Miner Res (2007) 0.95
Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice. Cancer Biother Radiopharm (2008) 0.94
Dual inhibition of ACE and NEP provides greater cardioprotection in mice with heart failure. J Card Fail (2004) 0.94
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density. Proteomics (2008) 0.94
A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgamma. J Atheroscler Thromb (2010) 0.94
Quasiparticle dynamics in reshaped helical Dirac cone of topological insulators. Proc Natl Acad Sci U S A (2013) 0.94
MNS1 is essential for spermiogenesis and motile ciliary functions in mice. PLoS Genet (2012) 0.93
Applications of magnetic microbubbles for theranostics. Theranostics (2012) 0.93
HIV trends and related risk factors among men having sex with men in mainland China: findings from a systematic literature review. Southeast Asian J Trop Med Public Health (2011) 0.93
[Evaluation of a pilot study on needle and syringe exchange program among injecting drug users in a community in Guangdong, China]. Zhonghua Yu Fang Yi Xue Za Zhi (2004) 0.93
Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa. BMC Med (2010) 0.93
Cinnamaldehyde reduction of platelet aggregation and thrombosis in rodents. Thromb Res (2006) 0.93
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice. Am J Physiol Gastrointest Liver Physiol (2012) 0.93
Incorporation of biodegradable electrospun fibers into calcium phosphate cement for bone regeneration. Acta Biomater (2009) 0.93
Biflavonoids from Caper (Capparis spinosa L.) fruits and their effects in inhibiting NF-kappa B activation. J Agric Food Chem (2011) 0.92
Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling. Hippocampus (2013) 0.92
Effect of salvianolic acid B and paeonol on blood lipid metabolism and hemorrheology in myocardial ischemia rabbits induced by pituitruin. Int J Mol Sci (2010) 0.92