Published in Biochem Biophys Res Commun on December 15, 1989
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci U S A (1991) 5.07
Structure of the human cyclo-oxygenase-2 gene. Biochem J (1994) 1.97
Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax (2001) 1.95
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J (1995) 1.74
Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase. Proc Natl Acad Sci U S A (1994) 1.69
The cyclooxygenases. Genome Biol (2004) 1.55
Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog Lipid Res (2007) 1.52
Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells. Proc Natl Acad Sci U S A (1991) 1.47
Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis. Mol Cell Biol (2009) 1.45
Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. J Immunol (2008) 1.07
Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats. Gut (1996) 1.06
Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation. Mol Cell Biol (2003) 1.05
Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. Arthritis Res Ther (2004) 1.01
Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal (2010) 0.98
Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). Pharmacogenet Genomics (2007) 0.97
Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia (2010) 0.94
Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. Neoplasia (1999) 0.94
Bioactive lipids in Trypanosoma cruzi infection. Adv Parasitol (2011) 0.93
Effect of a cyclooxygenase-2 inhibitor on postexercise muscle protein synthesis in humans. Am J Physiol Endocrinol Metab (2009) 0.92
Proliferation-dependent changes in release of arachidonic acid from endothelial cells. J Clin Invest (1994) 0.89
Effects of prostaglandins and COX-inhibiting drugs on skeletal muscle adaptations to exercise. J Appl Physiol (1985) (2013) 0.87
Characterization of a novel transcript of prostaglandin endoperoxide H synthase 1 with a tissue-specific profile of expression. Biochem J (1999) 0.85
Flurbiprofen, a cyclooxygenase inhibitor, protects mice from hepatic ischemia/reperfusion injury by inhibiting GSK-3β signaling and mitochondrial permeability transition. Mol Med (2012) 0.83
Cyclooxygenase-1 and -2: molecular targets for cervical neoplasia. J Cancer Prev (2013) 0.82
Enhanced prostacyclin synthesis in endothelial cells by retrovirus-mediated transfer of prostaglandin H synthase cDNA. J Clin Invest (1993) 0.79
The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1. Neoplasia (2001) 0.78
The role of prostaglandins in gastric mucosal protection. Trans Am Clin Climatol Assoc (1996) 0.76
Molecular evolution of enzymes involved in the arachidonic acid cascade. Mediators Inflamm (1992) 0.75
Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. Inflammation (2001) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1990) 0.75
Effect of common single nucleotide polymorphisms in COX-1 gene on related metabolic activity in diabetic patients treated with acetylsalicylic acid. Arch Med Sci (2013) 0.75
Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature (1984) 8.02
Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature (1987) 6.66
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter. Nature (1986) 5.28
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature (1989) 5.21
Structural homology of Torpedo californica acetylcholine receptor subunits. Nature (1983) 4.70
Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature (1989) 4.55
Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit. Nature (1994) 4.34
The naming of voltage-gated calcium channels. Neuron (1994) 4.31
Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence. Nature (1982) 3.69
Primary structure of the alpha-subunit of transducin and its relationship to ras proteins. Nature (1985) 3.28
Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs. Nature (1990) 3.16
Nomenclature of voltage-gated calcium channels. Neuron (2000) 3.09
Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor. Nature (1983) 2.78
Subcellular membrane topology and turnover of a rat hepatic binding protein specific for asialoglycoproteins. J Biol Chem (1979) 2.59
Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology (1993) 2.57
Primary structures of beta- and delta-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences. Nature (1983) 2.55
Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. Nature (1986) 2.28
Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunits. Neuron (1993) 2.14
Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nat Med (1996) 2.12
Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue. Nucleic Acids Res (1986) 2.04
Localization in the II-III loop of the dihydropyridine receptor of a sequence critical for excitation-contraction coupling. J Biol Chem (1998) 2.02
Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors. J Gen Physiol (1994) 2.00
Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem (1998) 1.87
Primary structure of chicken liver acetyl-CoA carboxylase deduced from cDNA sequence. J Biol Chem (1988) 1.84
Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells. Proc Natl Acad Sci U S A (2001) 1.63
Restoration of junctional tetrads in dysgenic myotubes by dihydropyridine receptor cDNA. Biophys J (1994) 1.58
Primary structure of the alpha-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence. FEBS Lett (1986) 1.57
Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs. Nature (1990) 1.57
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res (1999) 1.54
Non-invasive assessment of cardiac output during exercise in healthy young humans: comparison between Modelflow method and Doppler echocardiography method. Acta Physiol Scand (2003) 1.54
Cytoplasmic and nuclear polyglutamine aggregates in SCA6 Purkinje cells. Neurology (2001) 1.53
Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry (1996) 1.49
Detection of capillary protein leakage by indocyanine green and glucose dilutions in septic patients. Crit Care Med (2000) 1.48
Purification, characterization, and cloning of enamel matrix serine proteinase 1. J Dent Res (1998) 1.46
Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel. EMBO J (2001) 1.45
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur J Biochem (1994) 1.45
Searches for Lepton flavor violation in the decays tau{+/-}-->e{+/-}gamma and tau{+/-}-->mu{+/-}gamma. Phys Rev Lett (2010) 1.44
Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit. Proc Natl Acad Sci U S A (1991) 1.44
Feedback control of cyclooxygenase-2 expression through PPARgamma. J Biol Chem (2000) 1.40
Porcine amelogenins. Calcif Tissue Int (1994) 1.39
The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. Proc Natl Acad Sci U S A (2000) 1.36
Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel. Proc Natl Acad Sci U S A (2000) 1.36
Selective adsorption of porcine-amelogenins onto hydroxyapatite and their inhibitory activity on hydroxyapatite growth in supersaturated solutions. Calcif Tissue Int (1987) 1.31
Sheathlin: cloning, cDNA/polypeptide sequences, and immunolocalization of porcine enamel sheath proteins. J Dent Res (1997) 1.28
Immunochemical and immunohistochemical studies, using antisera against porcine 25 kDa amelogenin, 89 kDa enamelin and the 13-17 kDa nonamelogenins, on immature enamel of the pig and rat. Histochemistry (1991) 1.26
Cloning and characterization of porcine enamelin mRNAs. J Dent Res (1997) 1.25
Primary structure of the beta-subunit of bovine transducin deduced from the cDNA sequence. FEBS Lett (1985) 1.24
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivo. Mol Cell (1998) 1.24
Primary sequence of arginine transfer RNA from Escherichia coli. Biochem Biophys Res Commun (1972) 1.24
L-serine production by a methylotroph and its related enzymes. Appl Microbiol Biotechnol (1993) 1.23
Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases. J Biol Chem (1999) 1.22
Molecular evolution of biotin-dependent carboxylases. Eur J Biochem (1993) 1.20
Identity of molecular structure of Shiga-like toxin I (VT1) from Escherichia coli O157:H7 with that of Shiga toxin. Microb Pathog (1988) 1.20
Micelle structure of amelogenin in porcine secretory enamel. J Dent Res (2007) 1.19
Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. FEBS Lett (1988) 1.19
Co-expression in CHO cells of two muscle proteins involved in excitation-contraction coupling. J Muscle Res Cell Motil (1995) 1.19
Redundancy in the signaling pathways and promoter elements regulating cyclooxygenase-2 gene expression in endotoxin-treated macrophage/monocytic cells. J Biol Chem (2000) 1.17
Coupling between cyclooxygenase, terminal prostanoid synthase, and phospholipase A2. J Biol Chem (2001) 1.17
Enamelysin (matrix metalloproteinase-20): localization in the developing tooth and effects of pH and calcium on amelogenin hydrolysis. J Dent Res (1998) 1.17
Continued high albumin production by multicellular spheroids of adult rat hepatocytes formed in the presence of liver-derived proteoglycans. Biochem Biophys Res Commun (1989) 1.17
Primary structure of alpha-tocopherol transfer protein from rat liver. Homology with cellular retinaldehyde-binding protein. J Biol Chem (1993) 1.16
Primary structure of the alpha-subunit of bovine adenylate cyclase-stimulating G-protein deduced from the cDNA sequence. FEBS Lett (1986) 1.16
Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. Cancer Res (2001) 1.15
Mass screening for hepatocellular carcinoma: experience in Hokkaido, Japan. J Gastroenterol Hepatol (1994) 1.15
Acetyl-coenzyme-A carboxylase from rat liver. Subunit structure and proteolytic modification. Eur J Biochem (1975) 1.14
Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. Biochem J (1995) 1.13
Abundant expression and cytoplasmic aggregations of [alpha]1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6. Hum Mol Genet (1999) 1.12
Immunocytochemical and immunochemical detection of a 32 kDa nonamelogenin and related proteins in porcine tooth germs. Arch Histol Cytol (1991) 1.12
Inhibition of rat-liver acetyl-coenzyme-A carboxylase by palmitoyl-coenzyme A. Formation of equimolar enzyme-inhibitor complex. Eur J Biochem (1978) 1.12
Effective transduction and stable transgene expression in human blood cells by a third-generation lentiviral vector. Gene Ther (2003) 1.12
Function of a truncated dihydropyridine receptor as both voltage sensor and calcium channel. Nature (1992) 1.11
Nonurea sodium dodecyl sulfate-polyacrylamide gel electrophoresis with high-molarity buffers for the separation of proteins and peptides. Anal Biochem (1993) 1.11
Molecular structure of the nicotinic acetylcholine receptor. Cold Spring Harb Symp Quant Biol (1983) 1.10
Isolation of exfoliative toxin from Staphylococcus hyicus subsp. hyicus and its exfoliative activity in the piglet. Vet Microbiol (1991) 1.09
Association of calcium channel alpha1S and beta1a subunits is required for the targeting of beta1a but not of alpha1S into skeletal muscle triads. Proc Natl Acad Sci U S A (1998) 1.09
Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem Biophys Res Commun (1998) 1.09
Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells. J Biol Chem (1994) 1.08
IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells. Clin Exp Allergy (2011) 1.08
Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes. Proc Natl Acad Sci U S A (1990) 1.08
Proteolytic enzyme in porcine immature enamel. J Dent Res (1979) 1.07
Cystadenoma and cystadenocarcinoma of the pancreas. Hepatogastroenterology (1989) 1.07
Precise measurement of the e+e- --> pi+pi-(gamma) cross section with the initial state radiation method at BABAR. Phys Rev Lett (2009) 1.07
The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells. FEBS Lett (1994) 1.07
Importance of E-selectin (ELAM-1) and sialyl Lewis(a) in the adhesion of pancreatic carcinoma cells to activated endothelium. Int J Cancer (1993) 1.07
Calcium binding of enamel proteins and their derivatives with emphasis on the calcium-binding domain of porcine sheathlin. Arch Oral Biol (2001) 1.07
Prostacyclin-dependent apoptosis mediated by PPAR delta. J Biol Chem (2001) 1.06
Pars plana vitrectomy for cystoid macular edema secondary to sarcoid uveitis. Ophthalmology (2001) 1.05
Structural regions of the cardiac Ca channel alpha subunit involved in Ca-dependent inactivation. J Gen Physiol (1997) 1.05
Primary structure of delta subunit precursor of calf muscle acetylcholine receptor deduced from cDNA sequence. Eur J Biochem (1985) 1.05
Measurement of |V(cb)| and the form-factor slope in B --> Dl- nu(l) decays in events tagged by a fully reconstructed B meson. Phys Rev Lett (2010) 1.05
Development of an elliptical multipole wiggler at SPring-8. J Synchrotron Radiat (1998) 1.05
Discrimination of odors in olfactory bulb, pyriform-amygdaloid areas, and orbitofrontal cortex of the monkey. J Neurophysiol (1975) 1.05
A prospective, randomised comparison of single and three piece acrylic foldable intraocular lenses. Br J Ophthalmol (2004) 1.05
Possible roles of partial sequences at N- and C-termini of amelogenin in protein-enamel mineral interaction. J Dent Res (1989) 1.04
Family 19 chitinases of Streptomyces species: characterization and distribution. Microbiology (1999) 1.03
Inhibitory effects of long-chain acyl coenzyme A analogues on rat liver acetyl coenzyme A carboxylase. FEBS Lett (1979) 1.03
Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III. J Virol (1999) 1.02
[A successfully treated case of fundic varices by retrograde transvenous obliteration with balloon]. Nihon Shokakibyo Gakkai Zasshi (1991) 1.02
Molecular determinants of calcium-dependent inactivation in cardiac L-type calcium channels. Biochem Biophys Res Commun (1994) 1.01