Published in Diabetes Care on September 01, 2014
Look AHEAD: Action for Health in Diabetes (LookAHEAD) | NCT00017953
Identification of type 2 diabetes subgroups through topological analysis of patient similarity. Sci Transl Med (2015) 1.27
Impact of the Affordable Care Act on access to care for US adults with diabetes, 2011-2012. Prev Chronic Dis (2015) 1.16
Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention. Diabetes Care (2016) 0.83
The Look AHEAD Trial: Implications for Lifestyle Intervention in Type 2 Diabetes Mellitus. Prog Cardiovasc Dis (2015) 0.82
Exercise and type 2 diabetes: molecular mechanisms regulating glucose uptake in skeletal muscle. Adv Physiol Educ (2014) 0.81
Implications of Look AHEAD for clinical trials and clinical practice. Diabetes Obes Metab (2014) 0.80
Insights offered by economic analyses. Diabetes Care (2014) 0.79
Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. Am J Hypertens (2015) 0.78
How much will we pay to increase steps per day? Examining the cost-effectiveness of a pedometer-based lifestyle program in primary care. Prev Med Rep (2015) 0.77
Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc (2017) 0.77
Evidence based review of type 2 diabetes prevention and management in low and middle income countries. World J Diabetes (2016) 0.76
An Economic Evaluation of a Weight Loss Intervention Program for People with Serious Mental Illnesses Taking Antipsychotic Medications. Adm Policy Ment Health (2016) 0.76
Exercise and Regulation of Carbohydrate Metabolism. Prog Mol Biol Transl Sci (2015) 0.75
Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial. Obesity (Silver Spring) (2016) 0.75
Weight maintenance following the STRIDE lifestyle intervention for individuals taking antipsychotic medications. Obesity (Silver Spring) (2015) 0.75
Prediction of Incident Diabetes in the Jackson Heart Study Using High-Dimensional Machine Learning. PLoS One (2016) 0.75
George A. Bray, MD: Progress in Obesity-Multidisciplinary Research, Multidimensional Man. Diabetes Care (2016) 0.75
The Lifestyle Intervention for the Treatment of Diabetes study (LIFT Diabetes): Design and baseline characteristics for a randomized translational trial to improve control of cardiovascular disease risk factors. Contemp Clin Trials (2016) 0.75
Impact of a behavioral weight loss intervention on comorbidities in overweight and obese breast cancer survivors. Support Care Cancer (2016) 0.75
Predictors of Diet-Induced Weight Loss in Overweight Adults with Type 2 Diabetes. PLoS One (2016) 0.75
Relative differences in resting-state brain connectivity associated with long term intensive lifestyle intervention. Psychoneuroendocrinology (2016) 0.75
Cost of intervention delivery in a lifestyle weight loss trial in type 2 diabetes: results from the Look AHEAD clinical trial. Obes Sci Pract (2017) 0.75
Design and participant characteristics for a randomized effectiveness trial of an intensive lifestyle intervention to reduce cardiovascular risk in adults with type 2 diabetes: The I-D-HEALTH study. Contemp Clin Trials (2015) 0.75
Associations Between Cardiovascular Health and Health-Related Quality of Life, Behavioral Risk Factor Surveillance System, 2013. Prev Chronic Dis (2016) 0.75
Self-Reported Gastrointestinal Symptoms in Type 2 Diabetes Improve With an Intensive Lifestyle Intervention: Results From the Action for Health in Diabetes (Look AHEAD) Clinical Trial. Clin Diabetes (2015) 0.75
The Look AHEAD Trial: A Review and Discussion Of Its Outcomes. Curr Nutr Rep (2014) 0.75
Personalized multistep cognitive behavioral therapy for obesity. Diabetes Metab Syndr Obes (2017) 0.75
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA (2003) 25.44
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood) (2009) 12.45
Prevalence of obesity in the United States, 2009-2010. NCHS Data Brief (2012) 10.88
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med (2010) 8.77
The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring) (2006) 8.25
The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance. Ann Intern Med (2005) 6.63
Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15
Projecting the future diabetes population size and related costs for the U.S. Diabetes Care (2009) 3.34
A randomized study on the effect of weight loss on obstructive sleep apnea among obese patients with type 2 diabetes: the Sleep AHEAD study. Arch Intern Med (2009) 3.27
The 10-year cost-effectiveness of lifestyle intervention or metformin for diabetes prevention: an intent-to-treat analysis of the DPP/DPPOS. Diabetes Care (2012) 3.12
Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med (2012) 2.90
Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study. Int J Obes (Lond) (2009) 2.32
Direct medical cost of overweight and obesity in the USA: a quantitative systematic review. Obes Rev (2011) 1.95
The cost burden of diabetes mellitus: the evidence from Germany--the CoDiM study. Diabetologia (2006) 1.69
Effects of lifestyle intervention on health care costs: Improving Control with Activity and Nutrition (ICAN). J Am Diet Assoc (2007) 1.62
The development and description of the comparison group in the Look AHEAD trial. Clin Trials (2011) 1.46
Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Diabetes Care (2010) 1.39
Comparing behavioral weight loss modalities: incremental cost-effectiveness of an internet-based versus an in-person condition. Obesity (Silver Spring) (2011) 1.21
Medication cost savings associated with weight loss for obese non-insulin-dependent diabetic men and women. Prev Med (1995) 1.08
Direct costs and health-related resource utilisation in the 6 months after insulin initiation in German patients with type 2 diabetes mellitus in 2006: INSTIGATE study. Curr Med Res Opin (2008) 1.01
Future direct and indirect costs of obesity and the influence of gaining weight: results from the MONICA/KORA cohort studies, 1995-2005. Econ Hum Biol (2011) 0.91
Cost-effectiveness of a primary care intervention to treat obesity. Int J Obes (Lond) (2013) 0.91
Bariatric surgery: shedding the monetary weight of prescription costs in the managed care arena. Obes Surg (2004) 0.90
Cost-effectiveness of a low-carbohydrate diet and a standard diet in severe obesity. Obes Res (2005) 0.87
Four-year analysis of cardiovascular disease risk factors, depression symptoms, and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetes Care (2013) 0.85
Pharmaceutical cost savings of treating obesity with weight loss medications. Obes Res (1999) 0.82
Economic impact of moderate weight loss in patients with Type 2 diabetes: the Fremantle Diabetes Study. Diabet Med (2011) 0.81
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 15.58
Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials (2003) 9.97
Benefits of modest weight loss in improving cardiovascular risk factors in overweight and obese individuals with type 2 diabetes. Diabetes Care (2011) 5.50
Association of an intensive lifestyle intervention with remission of type 2 diabetes. JAMA (2012) 5.15
Effect of a long-term behavioural weight loss intervention on nephropathy in overweight or obese adults with type 2 diabetes: a secondary analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2014) 4.30
One-year weight losses in the Look AHEAD study: factors associated with success. Obesity (Silver Spring) (2009) 4.08
Four-year weight losses in the Look AHEAD study: factors associated with long-term success. Obesity (Silver Spring) (2011) 3.62
Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2014) 3.10
Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med (2012) 2.90
Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med (2009) 2.59
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
One-year changes in symptoms of depression and weight in overweight/obese individuals with type 2 diabetes in the Look AHEAD study. Obesity (Silver Spring) (2011) 1.97
Weight loss prevents urinary incontinence in women with type 2 diabetes: results from the Look AHEAD trial. J Urol (2012) 1.85
Do weight loss and adherence cluster within behavioral treatment groups? Obesity (Silver Spring) (2013) 1.83
Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial. Diabetes Care (2011) 1.78
Intensive lifestyle intervention improves physical function among obese adults with knee pain: findings from the Look AHEAD trial. Obesity (Silver Spring) (2010) 1.78
Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study. J Diabetes Complications (2008) 1.77
Exercise capacity and cardiovascular/metabolic characteristics of overweight and obese individuals with type 2 diabetes: the Look AHEAD clinical trial. Diabetes Care (2007) 1.50
Evaluation of early weight loss thresholds for identifying nonresponders to an intensive lifestyle intervention. Obesity (Silver Spring) (2014) 1.44
Correlates of health-related quality of life in overweight and obese adults with type 2 diabetes. Obesity (Silver Spring) (2006) 1.43
Effect of the look AHEAD study intervention on medication use and related cost to treat cardiovascular disease risk factors in individuals with type 2 diabetes. Diabetes Care (2010) 1.39
Action for Health in Diabetes (Look AHEAD) trial: baseline evaluation of selected nutrients and food group intake. J Am Diet Assoc (2009) 1.30
The long-term effectiveness of a lifestyle intervention in severely obese individuals. Am J Med (2013) 1.22
A 1-year lifestyle intervention for weight loss in individuals with type 2 diabetes reduces high C-reactive protein levels and identifies metabolic predictors of change: from the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 1.21
Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial. Diabetes Care (2014) 1.19
Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr (2012) 1.18
Consent for genetics studies among clinical trial participants: findings from Action for Health in Diabetes (Look AHEAD). Clin Trials (2006) 1.15
Patterns of weight change associated with long-term weight change and cardiovascular disease risk factors in the Look AHEAD Study. Obesity (Silver Spring) (2012) 1.12
Altered body composition in type 2 diabetes mellitus. Int J Obes (Lond) (2008) 1.10
Neighborhood and weight-related health behaviors in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2010) 1.07
Four-year change in cardiorespiratory fitness and influence on glycemic control in adults with type 2 diabetes in a randomized trial: the Look AHEAD Trial. Diabetes Care (2012) 1.02
Lifestyle intervention improves heart rate recovery from exercise in adults with type 2 diabetes: results from the Look AHEAD study. J Obes (2012) 1.01
Effect of 1 year of an intentional weight loss intervention on bone mineral density in type 2 diabetes: results from the Look AHEAD randomized trial. J Bone Miner Res (2012) 1.01
Neighborhood socioeconomic status, depression, and health status in the Look AHEAD (Action for Health in Diabetes) study. BMC Public Health (2011) 1.00
Cardiovascular disease risk factors, depression symptoms and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetologia (2010) 0.99
Long-term impact of behavioral weight loss intervention on cognitive function. J Gerontol A Biol Sci Med Sci (2014) 0.98
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol (2016) 0.98
Binge eating and weight loss outcomes in overweight and obese individuals with type 2 diabetes: results from the Look AHEAD trial. Arch Gen Psychiatry (2008) 0.96
Weight change in the first 2 months of a lifestyle intervention predicts weight changes 8 years later. Obesity (Silver Spring) (2015) 0.96
Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study. Obesity (Silver Spring) (2015) 0.94
Regression from prediabetes to normal glucose regulation is associated with reduction in cardiovascular risk: results from the Diabetes Prevention Program outcomes study. Diabetes Care (2014) 0.91
American association of clinical endocrinologists and american college of endocrinology position statement on the 2014 advanced framework for a new diagnosis of obesity as a chronic disease. Endocr Pract (2014) 0.89
Adiponectin and the mediation of HDL-cholesterol change with improved lifestyle: the Look AHEAD Study. J Lipid Res (2012) 0.88
Factors influencing enrollment of African Americans in the Look AHEAD trial. Clin Trials (2011) 0.88
FTO predicts weight regain in the Look AHEAD clinical trial. Int J Obes (Lond) (2013) 0.88
American association of clinical endocrinologists and american college of endocrinology consensus conference on obesity: building an evidence base for comprehensive action. Endocr Pract (2014) 0.88
Four-year analysis of cardiovascular disease risk factors, depression symptoms, and antidepressant medicine use in the Look AHEAD (Action for Health in Diabetes) clinical trial of weight loss in diabetes. Diabetes Care (2013) 0.85
Intensive lifestyle intervention reduces urinary incontinence in overweight/obese men with type 2 diabetes: results from the Look AHEAD trial. J Urol (2014) 0.85
Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention. J Gerontol A Biol Sci Med Sci (2014) 0.84
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet (2013) 0.84
Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial. Hum Hered (2013) 0.84
Intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 0.84
Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention. Diabetes Care (2016) 0.83
Prevalence and predictors of abnormal cardiovascular responses to exercise testing among individuals with type 2 diabetes: the Look AHEAD (Action for Health in Diabetes) study. Diabetes Care (2010) 0.82
Genetic modifiers of cardiorespiratory fitness response to lifestyle intervention. Med Sci Sports Exerc (2014) 0.81
Partial Meal Replacement Plan and Quality of the Diet at 1 Year: Action for Health in Diabetes (Look AHEAD) Trial. J Acad Nutr Diet (2015) 0.81
Effect of an intensive lifestyle intervention on atrial fibrillation risk in individuals with type 2 diabetes: the Look AHEAD randomized trial. Am Heart J (2015) 0.81
Implications of Look AHEAD for clinical trials and clinical practice. Diabetes Obes Metab (2014) 0.80
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial. Diabetologia (2015) 0.80
Weight-loss therapy in type 2 diabetes: effects of phentermine and topiramate extended release. Diabetes Care (2014) 0.79
Systolic Blood Pressure Control Among Individuals With Type 2 Diabetes: A Comparative Effectiveness Analysis of Three Interventions. Am J Hypertens (2015) 0.78
Prospective Association of GLUL rs10911021 With Cardiovascular Morbidity and Mortality Among Individuals With Type 2 Diabetes: The Look AHEAD Study. Diabetes (2015) 0.77
The Look AHEAD Trial: bone loss at 4-year follow-up in type 2 diabetes. Diabetes Care (2014) 0.77
Baseline predictors of missed visits in the Look AHEAD study. Obesity (Silver Spring) (2014) 0.77
Diabetic kidneys do deserve a lifestyle change. Lancet Diabetes Endocrinol (2014) 0.77
Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc (2017) 0.77
The relationship of social support with treatment adherence and weight loss in Latinos with type 2 diabetes. Obesity (Silver Spring) (2016) 0.76
Impact of weight loss on ankle-brachial index and interartery blood pressures. Obesity (Silver Spring) (2014) 0.76
Changes in regional body composition over 8 years in a randomized lifestyle trial: The look AHEAD study. Obesity (Silver Spring) (2016) 0.75
Cost of intervention delivery in a lifestyle weight loss trial in type 2 diabetes: results from the Look AHEAD clinical trial. Obes Sci Pract (2017) 0.75
Can an intensive diet and exercise program prevent knee pain among overweight adults at high risk? Arthritis Care Res (Hoboken) (2015) 0.75
Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women. Diabetes Care (2015) 0.75
A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes. Physiol Genomics (2015) 0.75
Impact of intensive lifestyle intervention on preference-based quality of life in type 2 diabetes: Results from the Look AHEAD trial. Obesity (Silver Spring) (2016) 0.75
Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study. Diabetologia (2017) 0.75
Genetic Predictors of Depressive Symptoms in the Look AHEAD Trial. Psychosom Med (2015) 0.75
The Look AHEAD study: a missed opportunity--authors' reply. Lancet Diabetes Endocrinol (2014) 0.75
Physical Function Following a Long-Term Lifestyle Intervention among Middle Aged and Older Adults with Type 2 Diabetes: the Look AHEAD Study. J Gerontol A Biol Sci Med Sci (2017) 0.75
The effect of intentional weight loss on fracture risk in persons with diabetes: results from the Look AHEAD Randomized Clinical Trial. J Bone Miner Res (2017) 0.75
Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial. Obesity (Silver Spring) (2020) 0.75