Published in J Physiol on April 01, 1989
Mechanism of augmented exercise hyperpnea in chronic heart failure and dead space loading. Respir Physiol Neurobiol (2012) 2.07
Cerebrovascular reactivity is associated with maximal aerobic capacity in healthy older adults. J Appl Physiol (1985) (2013) 1.68
Influence of cerebrovascular function on the hypercapnic ventilatory response in healthy humans. J Physiol (2006) 1.44
On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans. J Physiol (2011) 1.39
Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci (2011) 1.28
Measuring the ventilatory response to hypoxia. J Physiol (2007) 0.98
Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia. J Appl Physiol (1985) (2012) 0.94
Carbonic anhydrase and control of breathing: different effects of benzolamide and methazolamide in the anaesthetized cat. J Physiol (1995) 0.88
The effect of low-dose acetazolamide on the ventilatory CO2 response curve in the anaesthetized cat. J Physiol (1996) 0.86
The steady-state and rebreathing methods compared during morphine administration in humans. J Physiol (1989) 0.84
Ventilatory drive and the apnea-hypopnea index in six-to-twelve year old children. BMC Pulm Med (2004) 0.83
On a pseudo-rebreathing technique to assess the ventilatory sensitivity to carbon dioxide in man. J Physiol (1990) 0.81
Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. Am J Physiol Heart Circ Physiol (2015) 0.79
Effect on ventilation of papaverine administered to the brain stem of the anaesthetized cat. J Physiol (1991) 0.79
The influence of indomethacin on the ventilatory response to CO2 in newborn anaesthetized piglets. J Physiol (1994) 0.79
Adaptation of the respiratory controller contributes to the attenuation of exercise hyperpnea in endurance-trained athletes. Eur J Appl Physiol (2011) 0.78
The reproducibility of the response of the human newborn to CO2 measured by rebreathing and steady-state methods. J Physiol (1994) 0.78
Submissive hypercapnia: Why COPD patients are more prone to CO2 retention than heart failure patients. Respir Physiol Neurobiol (2015) 0.77
Differences in the control of breathing between Andean highlanders and lowlanders after 10 days acclimatization at 3850 m. J Physiol (2010) 0.77
Differences in the control of breathing between Himalayan and sea-level residents. J Physiol (2010) 0.76
THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN. J Clin Invest (1948) 22.75
A clinical method for assessing the ventilatory response to carbon dioxide. Australas Ann Med (1967) 5.61
Respiration and cerebral blood flow in metabolic acidosis and alkalosis in humans. J Appl Physiol (1969) 2.03
Blood-brain tissue Pco2 relationships and ventilation during rebreathing. J Appl Physiol (1967) 1.52
The ventilatory response to CO2 in chronic airways obstruction measured by a rebreathing method. Clin Sci (1968) 1.27
A comparison of the ventilatory response to carbon dioxide by steady-state and rebreathing methods during metabolic acidosis and alkalosis. Clin Sci Mol Med (1973) 1.14
Effect of intravenous dopamine on hypercapnic ventilatory response in humans. J Appl Physiol Respir Environ Exerc Physiol (1983) 1.10
THE IMMEDIATE CARBON DIOXIDE STORAGE CAPACITY OF MAN. Clin Sci (1964) 1.09
Variability of ventilatory responses to hypoxia and hypercapnia. J Appl Physiol Respir Environ Exerc Physiol (1977) 1.03
Effect of brain blood flow on hypoxic ventilatory response in humans. J Appl Physiol (1985) (1987) 0.94
A pseudo-rebreathing technique for assessing the ventilatory response to carbon dioxide in cats. J Physiol (1986) 0.89
Automatic correction for drift in an integrator for phasic signals. Med Biol Eng Comput (1977) 0.88
Respiratory responses to carbon dioxide transients in normal volunteers. Anesthesiology (1958) 0.87
Estimating medullary chemoreceptor blood flow from ventilatory-CO2 response transients: theory and data from anesthetized dogs. Ann Biomed Eng (1984) 0.84
Increased ventilatory response to CO 2 by rebreathing in consecutive daily trials. Jpn J Physiol (1972) 0.81
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol Biol Cell (1995) 6.23
Opioid-induced respiratory depression in paediatrics: a review of case reports. Br J Anaesth (2012) 3.39
Somatic hyperconversion diversifies the single Vh gene of the chicken with a high incidence in the D region. Cell (1989) 2.77
A single rearrangement event generates most of the chicken immunoglobulin light chain diversity. Cell (1985) 2.65
Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2. J Biol Chem (1994) 2.34
Current status of ketamine anaesthesia. Lancet (1971) 2.28
The Leiden anaesthesia simulator. Br J Anaesth (1994) 2.12
Ventilatory responses after major surgery and high dependency care. Br J Anaesth (2012) 2.05
Pharmacodynamics of propofol in female patients. Anesthesiology (1992) 1.83
The pharmacodynamic interaction of propofol and alfentanil during lower abdominal surgery in women. Anesthesiology (1995) 1.65
Does training on an anaesthesia simulator lead to improvement in performance? Br J Anaesth (1994) 1.61
Two novel human and mouse DNA polymerases of the polX family. Nucleic Acids Res (2000) 1.58
Nonlinear analysis of epicardial atrial electrograms of electrically induced atrial fibrillation in man. J Cardiovasc Electrophysiol (1995) 1.56
Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia. J Comp Neurol (1997) 1.56
Sex differences in morphine analgesia: an experimental study in healthy volunteers. Anesthesiology (2000) 1.55
Adalimumab drug and antibody levels as predictors of clinical and laboratory response in patients with Crohn's disease. Aliment Pharmacol Ther (2014) 1.54
Effects of subanesthetic halothane on the ventilatory responses to hypercapnia and acute hypoxia in healthy volunteers. Anesthesiology (1994) 1.52
Computer-controlled infusion of alfentanil versus patient-controlled administration of morphine for postoperative analgesia: a double-blind randomized trial. Anesth Analg (1995) 1.48
Effect of propofol on peripheral vascular resistance during cardiopulmonary bypass. Br J Anaesth (1990) 1.44
Influence of age on the pharmacokinetics of alfentanil. Gender dependence. Clin Pharmacokinet (1990) 1.43
Evaluation of surgical conditions during laparoscopic surgery in patients with moderate vs deep neuromuscular block. Br J Anaesth (2013) 1.42
Unconscious learning during anaesthesia. Anaesthesia (1992) 1.42
Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. J Med Genet (2005) 1.40
Performance of computer-controlled infusion of propofol: an evaluation of five pharmacokinetic parameter sets. Anesth Analg (1995) 1.34
Clinical studies of induction agents. XXXVI: Ketamine. Br J Anaesth (1970) 1.32
Formation of the chicken B-cell repertoire: ontogenesis, regulation of Ig gene rearrangement, and diversification by gene conversion. Adv Immunol (1994) 1.24
Nucleotide sequence of the constant region of a chicken mu heavy chain immunoglobulin mRNA. Nucleic Acids Res (1983) 1.22
Permutation entropy of the electroencephalogram: a measure of anaesthetic drug effect. Br J Anaesth (2008) 1.19
Accidents, near accidents and complications during anaesthesia. A retrospective analysis of a 10-year period in a teaching hospital. Anaesthesia (1990) 1.18
Comparison of chemoreflex gains obtained with two different methods in cats. J Appl Physiol (1985) (1985) 1.17
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia. Anesthesiology (1984) 1.17
Reported significant observations during anaesthesia: a prospective analysis over an 18-month period. Br J Anaesth (1992) 1.16
Clinical studies of induction agents. 38. Effect of premedicants and supplements on ketamine anaesthesia. Br J Anaesth (1971) 1.16
Complete sequence of a chicken lambda light chain immunoglobulin derived from the nucleotide sequence of its mRNA. Proc Natl Acad Sci U S A (1983) 1.15
The influence of oxygen on the ventilatory response to carbon dioxide in man. J Physiol (1990) 1.14
Gender differences in opioid-mediated analgesia: animal and human studies. Anesthesiology (2000) 1.14
Clinical studies of induction agents. XXXIX: CT1341, a new steroid anaesthetic. Br J Anaesth (1971) 1.09
Propofol anesthesia and rational opioid selection: determination of optimal EC50-EC95 propofol-opioid concentrations that assure adequate anesthesia and a rapid return of consciousness. Anesthesiology (1997) 1.09
The dynamic relationship between end-tidal sevoflurane and isoflurane concentrations and bispectral index and spectral edge frequency of the electroencephalogram. Anesthesiology (1999) 1.08
The ecdysone response enhancer of the Fbp1 gene of Drosophila melanogaster is a direct target for the EcR/USP nuclear receptor. Mol Cell Biol (1994) 1.08
Nonlinear dynamics of epileptic seizures on basis of intracranial EEG recordings. Brain Topogr (1997) 1.07
G-protein-mediated interconversions of cell-surface cAMP receptors and their involvement in excitation and desensitization of guanylate cyclase in Dictyostelium discoideum. J Biol Chem (1986) 1.07
Pharmacodynamic interaction between propofol and alfentanil when given for induction of anesthesia. Anesthesiology (1996) 1.06
The pharmacokinetics of alfentanil (R39209): a new opioid analgesic. Anesthesiology (1982) 1.03
Postoperative analgesic effects of three demand-dose sizes of fentanyl administered by patient-controlled analgesia. Anesth Analg (1998) 1.00
Which potent opioid? Important criteria for selection. Drugs (1987) 0.99
Acetazolamide and breathing. Does a clinical dose alter peripheral and central CO(2) sensitivity? Am J Respir Crit Care Med (1999) 0.98
Perioperative infusions in paediatric patients: rationale for using Ringer-lactate solution with low dextrose concentration. J Clin Pharm Ther (2003) 0.97
High-density molecular map of chromosome region harboring stripe-rust resistance genes YrH52 and Yr15 derived from wild emmer wheat, Triticum dicoccoides. Genetica (2000) 0.95
Sex differences in morphine-induced ventilatory depression reside within the peripheral chemoreflex loop. Anesthesiology (1999) 0.94
Quantification of the EEG effect of midazolam by aperiodic analysis in volunteers. Pharmacokinetic/pharmacodynamic modelling. Clin Pharmacokinet (1990) 0.94
Dynamics of ventilatory response to step changes in PCO2 of blood perfusing the brain stem. J Appl Physiol (1985) (1989) 0.92
Influences of morphine on the ventilatory response to isocapnic hypoxia. Anesthesiology (1997) 0.91
Effects of sounds presented during general anaesthesia on postoperative course. Br J Anaesth (1988) 0.90
A randomised comparison of intravenous remifentanil patient-controlled analgesia with epidural ropivacaine/sufentanil during labour. Int J Obstet Anesth (2011) 0.90
Ventilatory sensitivities of peripheral and central chemoreceptors of young piglets to inhalation of CO2 in air. Pediatr Res (1991) 0.90
A pseudo-rebreathing technique for assessing the ventilatory response to carbon dioxide in cats. J Physiol (1986) 0.89
The taming of ketamine. Anaesthesia (1973) 0.89
Gender differences in the pharmacokinetics of propofol in elderly patients during and after continuous infusion. Br J Anaesth (2001) 0.89
Propofol for monitored anesthesia care: implications on hypoxic control of cardiorespiratory responses. Anesthesiology (2000) 0.89
The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception. Anesth Analg (2001) 0.89
Effect of three different anaesthetic agents on the postoperative production of cardiac troponin T in paediatric cardiac surgery. Br J Anaesth (2005) 0.88
Mechanism of action of an epidural top-up in combined spinal epidural anesthesia. Anesth Analg (1996) 0.88
First-pass lung uptake and pulmonary clearance of propofol: assessment with a recirculatory indocyanine green pharmacokinetic model. Anesthesiology (1999) 0.88
Motor control in complex regional pain syndrome: a kinematic analysis. Pain (2012) 0.88
Transcription, beta-like DNA polymerases and hypermutation. Philos Trans R Soc Lond B Biol Sci (2001) 0.88
Carbonic anhydrase and control of breathing: different effects of benzolamide and methazolamide in the anaesthetized cat. J Physiol (1995) 0.88
The effects of hypoxia on the ventilatory response to sudden changes in CO2 in newborn piglets. J Physiol (1992) 0.88
The pharmacokinetics of sufentanil in surgical patients. Anesthesiology (1984) 0.87
Lumbar epidural catheter insertion: the midline vs. the paramedian approach. Eur J Anaesthesiol (2005) 0.87
Influence of 0.1 minimum alveolar concentration of sevoflurane, desflurane and isoflurane on dynamic ventilatory response to hypercapnia in humans. Br J Anaesth (1998) 0.87
Effect of thiopentone, etomidate and propofol on systemic vascular resistance during cardiopulmonary bypass. Br J Anaesth (1991) 0.86
Effects of high-dose fentanyl anesthesia on the electroencephalogram. Anesthesiology (1981) 0.86
Gut permeability in paediatric cardiac surgery. Br J Anaesth (2004) 0.86
Some cardiovascular effects of ketamine in man. Br J Pharmacol (1971) 0.86
Differential effects of propofol and nitrous oxide on posterior tibial nerve somatosensory cortical evoked potentials during alfentanil anaesthesia. Br J Anaesth (1991) 0.86
Low-dose acetazolamide reduces CO(2)-O(2) stimulus interaction within the peripheral chemoreceptors in the anaesthetised cat. J Physiol (2001) 0.86
Comparison of nitroglycerine, verapamil and nifedipine in the management of arterial pressure during coronary artery surgery. Br J Anaesth (1986) 0.86
Respiratory sites of action of propofol: absence of depression of peripheral chemoreflex loop by low-dose propofol. Anesthesiology (2001) 0.86
Isolation of microsatellite and RAPD markers flanking the Yr15 gene of wheat using NILs and bulked segregant analysis. Genome (1999) 0.85
The neuronal nitric oxide synthase inhibitor 7-nitroindazole (7-NI) and morphine act independently on the control of breathing. Br J Anaesth (2000) 0.85
Recirculatory pharmacokinetics and pharmacodynamics of rocuronium in patients: the influence of cardiac output. Anesthesiology (2001) 0.85
Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice. Br J Anaesth (2003) 0.85
The ventilatory response to CO2 of the peripheral and central chemoreflex loop before and after sustained hypoxia in man. J Physiol (1992) 0.85
Fentanyl and convulsions. Anesth Analg (1983) 0.85
High-inspired oxygen concentration further impairs opioid-induced respiratory depression. Br J Anaesth (2013) 0.84
An anaphylactic reaction to protamine in a patient allergic to fish. Anesthesiology (1981) 0.84
Modeling population pharmacokinetics of lidocaine: should cardiac output be included as a patient factor? Anesthesiology (2001) 0.84
A comparison of the effects of propofol and midazolam on memory during two levels of sedation by using target-controlled infusion. Anesth Analg (2000) 0.83
The epidural "top-up" in combined spinal-epidural anesthesia: the effect of volume versus dose. Anesth Analg (1999) 0.83
Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation. Anesthesiology (1996) 0.83
Pharmacokinetics of high-dose fentanyl. A study in patients undergoing cardiac surgery. Br J Anaesth (1980) 0.83
A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia. Eur J Pain (2013) 0.83