Advanced prostate cancer - patient survival and potential impact of enzalutamide and other emerging therapies.

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Published in Ther Clin Risk Manag on August 16, 2014

Authors

Nihar K Patel1, Antoine Finianos1, Kristen D Whitaker1, Jeanny B Aragon-Ching1

Author Affiliations

1: Department of Medicine, Division of Hematology and Oncology, George Washington University Medical Center, Washington, DC, USA.

Associated clinical trials:

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer | NCT01057810

A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer (Prospect) | NCT01322490

Provenge® (Sipuleucel-T) Active Cellular Immunotherapy Treatment of Metastatic Prostate Cancer After Failing Hormone Therapy | NCT00065442

Study Comparing Orteronel Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer | NCT01193257

XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer (TROPIC) | NCT00417079

A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases (ALSYMPCA) | NCT00699751

Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer (COMET-2) | NCT01522443

Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100 (COMET-1) | NCT01605227

Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer (SYNERGY) | NCT01188187

A Study of Tasquinimod in Men With Metastatic Castrate Resistant Prostate Cancer | NCT01234311

Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for 2nd Line Chemotherapy in Prostate Cancer (AFFINITY) | NCT01578655

Provenge (TM) for the Treatment of Hormone Sensitive Prostate Cancer (PROTECT) | NCT00779402

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer (SPARTAN) | NCT01946204

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