Published in Front Immunol on August 21, 2014
Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms. Mediators Inflamm (2015) 1.48
Complement in disease: a defence system turning offensive. Nat Rev Nephrol (2016) 0.97
The Macrophage Switch in Obesity Development. Front Immunol (2016) 0.93
Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q. Atherosclerosis (2016) 0.91
RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment. Neurobiol Dis (2015) 0.85
Macrophages at the fork in the road to health or disease. Front Immunol (2015) 0.82
Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation. PLoS Negl Trop Dis (2015) 0.79
Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity. J Transl Med (2017) 0.78
Adiponectin: a versatile player of innate immunity. J Mol Cell Biol (2016) 0.78
Soluble IgM links apoptosis to complement activation in early alcoholic liver disease in mice. Mol Immunol (2016) 0.77
Complement Component C1q Programs a Pro-Efferocytic Phenotype while Limiting TNFα Production in Primary Mouse and Human Macrophages. Front Immunol (2016) 0.76
Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts. Curr Opin Organ Transplant (2016) 0.75
Mannose-Binding Lectin: Biologic Characteristics and Role in the Susceptibility to Infections and Ischemia-Reperfusion Related Injury in Critically Ill Neonates. J Immunol Res (2017) 0.75
Complement Protein C1q Enhances Macrophage Foam Cell Survival and Efferocytosis. J Immunol (2016) 0.75
Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. J Neuroinflammation (2017) 0.75
Transcriptomic Insights into the Response of Placenta and Decidua Basalis to the CpG Oligodeoxynucleotide Stimulation in Non-Obese Diabetic Mice and Wild-Type Controls. Int J Mol Sci (2016) 0.75
Production of complement components by cells of the immune system. Clin Exp Immunol (2017) 0.75
Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies. PLoS Pathog (2016) 0.75
Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice. J Biol Chem (2016) 0.75
Complement in Kidney Transplantation. Front Med (Lausanne) (2017) 0.75
Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice. PLoS One (2017) 0.75
Combined genotypes of the MBL2 gene related to low mannose-binding lectin levels are associated with vaso-occlusive events in children with sickle cell anemia. Genet Mol Biol (2017) 0.75
Upregulation of Early and Downregulation of Terminal Pathway Complement Genes in Subcutaneous Adipose Tissue and Adipocytes in Acquired Obesity. Front Immunol (2017) 0.75
Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy. Front Immunol (2017) 0.75
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest (1998) 13.05
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (2003) 9.79
Adiponectin and adiponectin receptors. Endocr Rev (2005) 8.46
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med (2007) 5.89
The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep (2014) 4.97
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J Exp Med (2001) 4.54
Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J Exp Med (1983) 3.96
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med (2000) 3.65
The chemotactic receptor for human C5a anaphylatoxin. Nature (1991) 3.15
Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype. J Immunol (2008) 3.07
The role of the anaphylatoxins in health and disease. Mol Immunol (2009) 2.95
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration. Cell Metab (2013) 2.92
CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell (2006) 2.89
C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. J Immunol (1997) 2.69
Complement-dependent clearance of apoptotic cells by human macrophages. J Exp Med (1998) 2.69
M1 and M2 Macrophages: Oracles of Health and Disease. Crit Rev Immunol (2012) 2.49
Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol (2007) 2.25
Recent advances in arginine metabolism: roles and regulation of the arginases. Br J Pharmacol (2009) 2.24
Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. J Exp Med (1994) 2.15
Dendritic cells and cytokines in human inflammatory and autoimmune diseases. Cytokine Growth Factor Rev (2008) 2.13
C1q, autoimmunity and apoptosis. Immunobiology (2002) 1.94
C5L2, a nonsignaling C5A binding protein. Biochemistry (2003) 1.90
The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74). J Biol Chem (2001) 1.80
Fine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensis. PLoS Pathog (2013) 1.71
Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. J Immunol (2009) 1.66
C1q and systemic lupus erythematosus. Immunobiology (1998) 1.63
Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue. Crit Rev Immunol (2001) 1.61
Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages. J Exp Med (1985) 1.60
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells. J Immunol (2012) 1.57
Complement deficiency states and associated infections. Mol Immunol (2011) 1.57
Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages. J Immunol (1987) 1.51
Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab (2011) 1.49
Structure-function relationships of complement receptor type 1. Immunol Rev (2001) 1.47
Complement receptor type 1 (CR1, CD35) is a receptor for C1q. Immunity (1997) 1.44
The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein. J Biol Chem (2003) 1.41
Complement in the brain. Mol Immunol (2011) 1.41
C1q and its growing family. Immunobiology (2006) 1.40
C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. J Leukoc Biol (2006) 1.40
CTRP family: linking immunity to metabolism. Trends Endocrinol Metab (2012) 1.38
beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. J Immunol (1994) 1.38
C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis. Arthritis Rheum (2009) 1.37
Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice. Am J Pathol (2007) 1.36
Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors. Eur J Immunol (1991) 1.35
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol (2010) 1.34
C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. J Immunol (2009) 1.32
C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production. J Neurochem (2009) 1.25
Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. J Immunol (2008) 1.20
Chemotaxis by a CNS macrophage, the microglia. J Neurosci Res (1990) 1.20
Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. J Immunol (2013) 1.20
C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. Blood (2013) 1.18
Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes. J Biol Chem (2007) 1.15
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol (2014) 1.15
Directing an appropriate immune response: the role of defense collagens and other soluble pattern recognition molecules. Curr Drug Targets (2008) 1.15
Potent induction of IFN-alpha and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus. J Immunol (2009) 1.11
Modified low density lipoproteins differentially bind and activate the C1 complex of complement. Mol Immunol (2006) 1.08
The complement system in systemic lupus erythematosus: an update. Ann Rheum Dis (2014) 1.08
Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors. Biol Chem (2010) 1.08
Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells. Clin Exp Immunol (2009) 1.07
Role of complement in Mycobacterium avium pathogenesis: in vivo and in vitro analyses of the host response to infection in the absence of complement component C3. Infect Immun (2001) 1.06
C1q and phagocytosis: the perfect complement to a good meal. J Leukoc Biol (2012) 1.05
The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cells. Arthritis Rheum (2007) 1.05
Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J Biol Chem (1996) 1.01
The complement system in human cardiometabolic disease. Mol Immunol (2014) 1.01
Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition. J Mol Biol (2011) 1.00
Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes. J Immunol (2011) 1.00
Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells. J Immunol (2012) 0.98
Innate immune proteins C1q and mannan-binding lectin enhance clearance of atherogenic lipoproteins by human monocytes and macrophages. J Immunol (2010) 0.95
The C5a complement activation peptide increases IL-1beta and IL-6 release from amyloid-beta primed human monocytes: implications for Alzheimer's disease. J Neuroimmunol (2000) 0.95
Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodies. Immunology (1999) 0.95
Z39Ig is co-expressed with activated macrophage genes. Biochim Biophys Acta (2002) 0.93
Induction of murine macrophage TNF-alpha synthesis by Mycobacterium avium is modulated through complement-dependent interaction via complement receptors 3 and 4 in relation to M. avium glycopeptidolipid. FEMS Microbiol Lett (2005) 0.90
Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosis. J Biol Chem (2013) 0.89
IL-4 down-regulates anaphylatoxin receptors in monocytes and dendritic cells and impairs anaphylatoxin-induced migration in vivo. J Immunol (2003) 0.87
Transcriptional regulation of the murine C5a receptor gene: NF-Y is required for basal and LPS induced expression in macrophages and endothelial cells. Mol Immunol (2005) 0.86
The CD11b-integrin (ITGAM) and systemic lupus erythematosus. Lupus (2013) 0.85
Ficolins in complement activation. Mol Immunol (2012) 0.85
Regulatory effects of C5a on IL-17A, IL-17F, and IL-23. Front Immunol (2013) 0.82
Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins. Inflamm Res (2014) 0.82
Complement protein C1q and adiponectin stimulate Mer tyrosine kinase-dependent engulfment of apoptotic cells through a shared pathway. J Innate Immun (2014) 0.82
Mannan-binding lectin in cardiovascular disease. Biomed Res Int (2014) 0.81