Organoid cultures derived from patients with advanced prostate cancer.

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🔗 View Article (PMC 4237931)

Published in Cell on September 04, 2014

Authors

Dong Gao1, Ian Vela2, Andrea Sboner3, Phillip J Iaquinta1, Wouter R Karthaus4, Anuradha Gopalan5, Catherine Dowling2, Jackline N Wanjala1, Eva A Undvall6, Vivek K Arora7, John Wongvipat1, Myriam Kossai8, Sinan Ramazanoglu9, Luendreo P Barboza1, Wei Di1, Zhen Cao1, Qi Fan Zhang1, Inna Sirota1, Leili Ran1, Theresa Y MacDonald8, Himisha Beltran10, Juan-Miguel Mosquera11, Karim A Touijer12, Peter T Scardino12, Vincent P Laudone12, Kristen R Curtis13, Dana E Rathkopf14, Michael J Morris14, Daniel C Danila14, Susan F Slovin14, Stephen B Solomon15, James A Eastham12, Ping Chi16, Brett Carver2, Mark A Rubin11, Howard I Scher14, Hans Clevers4, Charles L Sawyers17, Yu Chen18

Author Affiliations

1: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
2: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
3: Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Institute for Precision Medicine of Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA.
4: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT, Utrecht, The Netherlands.
5: Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
6: Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
7: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
8: Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA.
9: Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA.
10: Institute for Precision Medicine of Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA.
11: Institute for Precision Medicine of Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA.
12: Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
13: Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
14: Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
15: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
16: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
17: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: sawyersc@mskcc.org.
18: Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: cheny1@mskcc.org.

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