Published in J Am Chem Soc on September 24, 2014
Near-IR Light-Mediated Cleavage of Antibody-Drug Conjugates Using Cyanine Photocages. Angew Chem Int Ed Engl (2015) 1.08
Electrophile-integrating Smiles rearrangement provides previously inaccessible C4'-O-alkyl heptamethine cyanine fluorophores. Org Lett (2015) 0.84
Reactive Species Involved in the Regioselective Photooxidation of Heptamethine Cyanines. Chem Sci (2015) 0.83
Near infrared light mediated release of doxorubicin using upconversion nanoparticles. Chem Commun (Camb) (2015) 0.79
Rapid Bioorthogonal Chemistry Turn-on through Enzymatic or Long Wavelength Photocatalytic Activation of Tetrazine Ligation. J Am Chem Soc (2016) 0.79
Impact of Substituents in Tumor Uptake and Fluorescence Imaging Ability of Near-Infrared Cyanine-like Dyes. Photochem Photobiol (2015) 0.78
Nebraska Red: a phosphinate-based near-infrared fluorophore scaffold for chemical biology applications. Chem Commun (Camb) (2016) 0.77
A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol (2016) 0.77
A Thioacetal Photocage Designed for Dual Release: Application in the Quantitation of Therapeutic Release by Synchronous Reporter Decaging. Chembiochem (2016) 0.77
Efficient Red Light Photo-Uncaging of Active Molecules in Water Upon Assembly into Nanoparticles. Chem Sci (2015) 0.76
Fluorinated Photodynamic Therapy Device Tips and their Resistance to Fouling for In Vivo Sensitizer Release. Photochem Photobiol (2015) 0.75
Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates. Mol Biosyst (2016) 0.75
In Vivo Activation of Duocarmycin-Antibody Conjugates by Near-Infrared Light. ACS Cent Sci (2017) 0.75
Synthesis of BODIPY-Peptide Conjugates for Fluorescence Labeling of EGFR Overexpressing Cells. Bioconjug Chem (2017) 0.75
Illuminating developmental biology through photochemistry. Nat Chem Biol (2017) 0.75
A global double-fluorescent Cre reporter mouse. Genesis (2007) 17.86
In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol (2003) 10.76
A clearer vision for in vivo imaging. Nat Biotechnol (2001) 10.49
Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther (2004) 3.84
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. J Neurosci (2003) 3.26
Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat Methods (2007) 3.22
Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds. ACS Chem Biol (2009) 2.67
Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy. Chem Rev (2012) 2.49
Toxicity of organic fluorophores used in molecular imaging: literature review. Mol Imaging (2009) 2.21
Light-controlled tools. Angew Chem Int Ed Engl (2012) 1.96
Solvent-sensitive dyes to report protein conformational changes in living cells. J Am Chem Soc (2003) 1.57
Near IR heptamethine cyanine dye-mediated cancer imaging. Clin Cancer Res (2010) 1.44
Chromophore-assisted laser inactivation in cell biology. Trends Cell Biol (2008) 1.42
Merocyanine dyes with improved photostability. Org Lett (2007) 1.37
Principles and applications of the photochemical control of cellular processes. Chembiochem (2010) 1.33
In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles. Angew Chem Int Ed Engl (2012) 1.33
Ultra-stable organic fluorophores for single-molecule research. Chem Soc Rev (2014) 1.31
Light-induced decomposition of indocyanine green. Invest Ophthalmol Vis Sci (2008) 1.29
Light activation as a method of regulating and studying gene expression. Curr Opin Chem Biol (2009) 1.25
Spatially discrete, light-driven protein expression. Chem Biol (2002) 1.18
Site-specific prodrug release using visible light. J Am Chem Soc (2008) 1.07
Improved photostability and fluorescence properties through polyfluorination of a cyanine dye. Org Lett (2004) 1.04
Direct and sensitized photooxidation of cyanine dyes. Photochem Photobiol (1976) 1.03
Light activated recombination. J Am Chem Soc (2005) 1.03
Development of photostable near-infrared cyanine dyes. Chem Commun (Camb) (2010) 1.01
Two-photon uncaging: New prospects in neuroscience and cellular biology. Bioorg Med Chem (2010) 1.01
Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry. J Med Chem (2013) 1.00
Comparative effects of six intraocular vital dyes on retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2010) 0.96
Photophysical and photosensitizing properties of selected cyanines. J Photochem Photobiol B (2002) 0.93
Photocontrol of protein activity in cultured cells and zebrafish with one- and two-photon illumination. Chembiochem (2010) 0.93
Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas. Angew Chem Int Ed Engl (2013) 0.91
A cyclodextrin dimer with a photocleavable linker as a possible carrier for the photosensitizer in photodynamic tumor therapy. Proc Natl Acad Sci U S A (1999) 0.90
Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem (2012) 0.90
Cyclization-activated prodrugs. Basic carbamates of 4-hydroxyanisole. J Med Chem (1990) 0.90
Click and photo-unclick chemistry of aminoacrylate for visible light-triggered drug release. Chem Commun (Camb) (2012) 0.88
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Cell-mediated assembly of phototherapeutics. Angew Chem Int Ed Engl (2014) 0.85
Nucleic acid binders activated by light of selectable wavelength. Angew Chem Int Ed Engl (2007) 0.84
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. Chem Commun (Camb) (2013) 0.83
Photochemistry and Cytotoxicity Evaluation of Heptamethinecyanine Near Infrared (NIR) Dyes. Int J Mol Sci (2013) 0.77
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell (2010) 4.99
Kinetics of tamoxifen-regulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton. Dev Dyn (2006) 3.05
Uncoupling Sonic hedgehog control of pattern and expansion of the developing limb bud. Dev Cell (2008) 2.25
Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone. Proc Natl Acad Sci U S A (2007) 1.85
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development (2008) 1.79
Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet (2010) 1.35
Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. Mol Cell Biol (2006) 1.34
Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh. Development (2004) 1.27
A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses. Proc Natl Acad Sci U S A (2010) 1.20
beta-Catenin has sequential roles in the survival and specification of ventral dermis. Development (2008) 1.17
Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life. Proc Natl Acad Sci U S A (2010) 1.14
Transient activation of Wnt/{beta}-catenin signaling induces abnormal growth plate closure and articular cartilage thickening in postnatal mice. Am J Pathol (2009) 1.10
Tamoxifen-dependent, inducible Hoxb6CreERT recombinase function in lateral plate and limb mesoderm, CNS isthmic organizer, posterior trunk neural crest, hindgut, and tailbud. Dev Dyn (2009) 1.05
IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway. J Bone Miner Res (2011) 1.02
The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells. Mol Cell Biol (2012) 0.98
Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canal. J Orthop Res (2010) 0.98
Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS One (2009) 0.95
Enantioselective total synthesis of (+)-salvileucalin B. J Am Chem Soc (2011) 0.93
Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3. Dev Biol (2012) 0.91
Cyanine polyene reactivity: scope and biomedical applications. Org Biomol Chem (2015) 0.87
Deletion of SNAP-23 results in pre-implantation embryonic lethality in mice. PLoS One (2011) 0.85
Electrophile-integrating Smiles rearrangement provides previously inaccessible C4'-O-alkyl heptamethine cyanine fluorophores. Org Lett (2015) 0.84
Tracing the evolution of avian wing digits. Curr Biol (2013) 0.84
Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway. Genesis (2012) 0.83
Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates. Bioconjug Chem (2015) 0.83
Analysis of mutants with altered shh activity and posterior digit loss supports a biphasic model for shh function as a morphogen and mitogen. Dev Dyn (2011) 0.82
Rapid assembly of the salvileucalin B norcaradiene core. Org Lett (2010) 0.81
A role for the mesenchymal T-box gene Brachyury in AER formation during limb development. Development (2003) 0.81
Limb development: the rise and fall of retinoic acid. Curr Biol (2009) 0.80
Augmentation of revascularization and prevention of plasma leakage by angiopoietin-1 and vascular endothelial growth factor co-transfection in rats with experimental limb ischaemia. Acta Cardiol (2006) 0.80
The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling. FASEB J (2011) 0.77
Developmental biology: extending the limb and body with vectors and scalars. Curr Biol (2011) 0.77
Ventral tail bud mesenchyme is a signaling center for tail paraxial mesoderm induction. Dev Dyn (2004) 0.76
A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides. Anal Bioanal Chem (2015) 0.75
Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates. Mol Biosyst (2016) 0.75
Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold. J Org Chem (2016) 0.75