Formal modelling of toll like receptor 4 and JAK/STAT signalling pathways: insight into the roles of SOCS-1, interferon-β and proinflammatory cytokines in sepsis.

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Published in PLoS One on September 25, 2014

Authors

Rehan Zafar Paracha1, Jamil Ahmad2, Amjad Ali1, Riaz Hussain3, Umar Niazi4, Samar Hayat Khan Tareen2, Babar Aslam1

Author Affiliations

1: Atta-Ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan.
2: Research Center for Modeling and Simulation (RCMS), National University of Sciences and Technology (NUST), Islamabad, Pakistan.
3: Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
4: IBERS, Aberystwyth University, Edward Llwyd Building, Penglais Campus, Aberystwyth, Ceredigion, Wales, United Kingdom.

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