Published in Nat Chem Biol on October 05, 2014
Immunomodulatory spherical nucleic acids. Proc Natl Acad Sci U S A (2015) 0.90
The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response. EBioMedicine (2016) 0.88
Recent advances in the molecular design of synthetic vaccines. Nat Chem (2015) 0.85
Antigen-specific cytotoxic T lymphocytes target airway CD103(+) and CD11b(+) dendritic cells to suppress allergic inflammation. Mucosal Immunol (2015) 0.78
Synthetic self-adjuvanting glycopeptide cancer vaccines. Front Chem (2015) 0.76
From Immunologically Archaic to Neoteric Glycovaccines. Vaccines (Basel) (2017) 0.75
Vaccine development: NKT-cell adjuvants in conjugate. Nat Chem Biol (2014) 0.75
Innate immune recognition. Annu Rev Immunol (2001) 26.65
T cell receptor antagonist peptides induce positive selection. Cell (1994) 18.66
The biology of NKT cells. Annu Rev Immunol (2007) 14.43
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science (1997) 13.67
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature (1998) 12.70
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature (1998) 12.07
Taking dendritic cells into medicine. Nature (2007) 11.82
Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature (1998) 11.08
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature (1989) 7.52
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med (1994) 7.35
Continuous proliferation of murine antigen-specific helper T lymphocytes in culture. J Exp Med (1979) 7.20
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity (2005) 6.48
Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol (1999) 5.51
CD1 recognition by mouse NK1+ T lymphocytes. Science (1995) 5.33
In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma. J Exp Med (2005) 4.34
Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice. Immunity (1997) 3.74
Targeted disruption of the MHC class II Aa gene in C57BL/6 mice. Int Immunol (1993) 3.73
NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells. J Immunol (2003) 3.19
Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat Immunol (2005) 3.12
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors. Clin Cancer Res (2002) 2.86
Glycolipid antigen induces long-term natural killer T cell anergy in mice. J Clin Invest (2005) 2.85
Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors. Immunity (2009) 2.61
Apolipoprotein-mediated pathways of lipid antigen presentation. Nature (2005) 2.61
Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells. Science (1993) 2.43
An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family. Proc Natl Acad Sci U S A (1992) 2.43
Natural killer T cell ligand alpha-galactosylceramide enhances protective immunity induced by malaria vaccines. J Exp Med (2002) 2.38
Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc Natl Acad Sci U S A (2006) 2.34
Robust immune responses elicited by a fully synthetic three-component vaccine. Nat Chem Biol (2007) 2.24
CD1d-restricted help to B cells by human invariant natural killer T lymphocytes. J Exp Med (2003) 2.01
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol (2013) 1.91
Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells. J Exp Med (1999) 1.88
Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs. Nat Immunol (2010) 1.81
alpha-galactosylceramide induces early B-cell activation through IL-4 production by NKT cells. Cell Immunol (2000) 1.77
Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness. Nat Med (2004) 1.71
Alpha-galactosylceramide-induced iNKT cells suppress experimental allergic asthma in sensitized mice: role of IFN-gamma. Eur J Immunol (2005) 1.66
A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses. Proc Natl Acad Sci U S A (2004) 1.60
The CD1d-binding glycolipid alpha-galactosylceramide enhances humoral immunity to T-dependent and T-independent antigen in a CD1d-dependent manner. Immunology (2006) 1.44
The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. J Exp Med (2003) 1.31
Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity. Eur J Immunol (2000) 1.24
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells. J Biol Chem (2007) 1.23
Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide. Eur J Immunol (2005) 1.22
NKT cells provide help for dendritic cell-dependent priming of MHC class I-restricted CD8+ T cells in vivo. J Immunol (2003) 1.14
Scavenger receptors target glycolipids for natural killer T cell activation. J Clin Invest (2012) 1.13
alpha-Galactosylceramide, a ligand of natural killer T cells, inhibits allergic airway inflammation. Am J Respir Cell Mol Biol (2005) 1.12
Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens. J Immunol (2009) 1.09
Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model. J Allergy Clin Immunol (2004) 1.08
(Acyloxy)alkyl carbamates as novel bioreversible prodrugs for amines: increased permeation through biological membranes. J Med Chem (1988) 1.02
The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity. J Immunol (2010) 0.97
Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration. J Allergy Clin Immunol (2006) 0.96
Allergen-specific CTL require perforin expression to suppress allergic airway inflammation. J Immunol (2012) 0.93
Novel synthesis of alpha-galactosyl-ceramides and confirmation of their powerful NKT cell agonist activity. Carbohydr Res (2006) 0.91
Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines. Oncoimmunology (2013) 0.91
Stabilized integrin-targeting ternary LPD (lipopolyplex) vectors for gene delivery designed to disassemble within the target cell. Bioconjug Chem (2009) 0.87
Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype. Am J Respir Crit Care Med (2009) 0.85
High-affinity interactions between peptides and heat shock protein 70 augment CD8+ T lymphocyte immune responses. J Immunol (2006) 0.84
Conjugation of a TLR7 agonist and antigen enhances protection in the S. pneumoniae murine infection model. Eur J Pharm Biopharm (2014) 0.78
A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes. Free Radic Biol Med (2013) 0.80
Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids. Innate Immun (2014) 0.78
Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells. PLoS One (2015) 0.75
Activation-Induced TIM-4 Expression Identifies Differential Responsiveness of Intestinal CD103+ CD11b+ Dendritic Cells to a Mucosal Adjuvant. PLoS One (2016) 0.75
Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System. PLoS One (2015) 0.75
Type I interferon is required for T helper (Th) 2 induction by dendritic cells. EMBO J (2017) 0.75
Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis. Front Immunol (2017) 0.75
Fetal dendritic cells give mum a break. Immunol Cell Biol (2017) 0.75