Published in Proc Natl Acad Sci U S A on October 13, 2014
A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands. Mol Cell (2015) 1.75
The architecture of a eukaryotic replisome. Nat Struct Mol Biol (2015) 1.15
Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation. Elife (2015) 1.12
Chromosome Duplication in Saccharomyces cerevisiae. Genetics (2016) 1.11
A panoply of errors: polymerase proofreading domain mutations in cancer. Nat Rev Cancer (2016) 1.06
Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement. Proc Natl Acad Sci U S A (2015) 0.99
How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication. Mol Cell (2016) 0.92
CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination. Genes Dev (2017) 0.91
Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc Natl Acad Sci U S A (2017) 0.90
Cdc45 is limiting for replication initiation in humans. Cell Cycle (2016) 0.86
The Eukaryotic Replisome Goes Under the Microscope. Curr Biol (2016) 0.84
Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Mol Cell (2016) 0.82
DNA Polymerases Divide the Labor of Genome Replication. Trends Cell Biol (2016) 0.79
Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit. J Biol Chem (2015) 0.79
Evolution of replication machines. Crit Rev Biochem Mol Biol (2015) 0.78
Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint. PLoS Genet (2017) 0.78
Eukaryotic genome instability in light of asymmetric DNA replication. Crit Rev Biochem Mol Biol (2015) 0.77
Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest. Proc Natl Acad Sci U S A (2016) 0.77
The eukaryotic CMG helicase pumpjack and integration into the replisome. Nucleus (2016) 0.77
Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae. G3 (Bethesda) (2015) 0.76
Methods to study the coupling between replicative helicase and leading-strand DNA polymerase at the replication fork. Methods (2016) 0.76
Role of the Polymerase ϵ sub-unit DPB2 in DNA replication, cell cycle regulation and DNA damage response in Arabidopsis. Nucleic Acids Res (2016) 0.76
Elaborated Action of the Human Primosome. Genes (Basel) (2017) 0.75
Reconstitution of a eukaryotic replisome reveals the mechanism of asymmetric distribution of DNA polymerases. Nucleus (2016) 0.75
Replication Protein A Prohibits Diffusion of the PCNA Sliding Clamp along Single-Stranded DNA. Biochemistry (2017) 0.75
CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome. Proc Natl Acad Sci U S A (2017) 0.75
Cryo-EM of dynamic protein complexes in eukaryotic DNA replication. Protein Sci (2016) 0.75
Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4. G3 (Bethesda) (2016) 0.75
Breaking Symmetry - Asymmetric Histone Inheritance in Stem Cells. Trends Cell Biol (2017) 0.75
Centromere Stability: The Replication Connection. Genes (Basel) (2017) 0.75
Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork. Proc Natl Acad Sci U S A (2017) 0.75
Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase. Elife (2017) 0.75
Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. DNA Repair (Amst) (2016) 0.75
Bacterial and Eukaryotic Replisome Machines. JSM Biochem Mol Biol (2016) 0.75
Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks. Genes (Basel) (2017) 0.75
From structure to mechanism-understanding initiation of DNA replication. Genes Dev (2017) 0.75
Diverse roles of Dpb2, the non-catalytic subunit of DNA polymerase ε. Curr Genet (2017) 0.75
Mechanisms of DNA replication termination. Nat Rev Mol Cell Biol (2017) 0.75
Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks. Elife (2017) 0.75
Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome. Proc Natl Acad Sci U S A (2017) 0.75
Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand. Genome Res (2017) 0.75
Replication dynamics of the yeast genome. Science (2001) 7.56
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol (2006) 6.36
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc Natl Acad Sci U S A (2006) 5.66
Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Science (2007) 4.63
The Escherichia coli dnaB replication protein is a DNA helicase. J Biol Chem (1986) 4.56
A third essential DNA polymerase in S. cerevisiae. Cell (1990) 4.46
Division of labor at the eukaryotic replication fork. Mol Cell (2008) 4.41
Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. Mol Cell (2010) 4.24
GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev (2003) 3.53
DNA polymerases that propagate the eukaryotic DNA replication fork. Crit Rev Biochem Mol Biol (2005) 3.46
Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement. Cell (1996) 2.96
The structural basis for MCM2-7 helicase activation by GINS and Cdc45. Nat Struct Mol Biol (2011) 2.93
Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. Cell (2011) 2.40
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding. J Biol Chem (2003) 2.19
Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication. Genes Dev (2007) 2.17
A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J (2009) 2.17
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. J Biol Chem (1990) 2.06
Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Curr Biol (2013) 1.93
CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast. Genes Dev (2010) 1.86
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 1.75
Replisome architecture and dynamics in Escherichia coli. J Biol Chem (2006) 1.71
Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork. Nat Struct Mol Biol (2014) 1.59
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. Nucleic Acids Res (2007) 1.49
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol (2010) 1.45
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis. Proc Natl Acad Sci U S A (2012) 1.44
Ctf4 coordinates the progression of helicase and DNA polymerase alpha. Genes Cells (2009) 1.33
Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery. Cell Cycle (2009) 1.28
Dynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primase. Curr Opin Chem Biol (2011) 1.24
Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase. Proc Natl Acad Sci U S A (1992) 1.23
Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. J Biol Chem (2011) 1.21
Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication. EMBO J (2014) 1.14
Influence of the human cohesion establishment factor Ctf4/AND-1 on DNA replication. J Biol Chem (2010) 1.10
Origin plasticity during budding yeast DNA replication in vitro. EMBO J (2014) 1.08
Collaborative coupling between polymerase and helicase for leading-strand synthesis. Nucleic Acids Res (2012) 1.08
Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication. Genes Cells (2013) 0.98
Double-stranded DNA binding, an unusual property of DNA polymerase epsilon, promotes epigenetic silencing in Saccharomyces cerevisiae. J Biol Chem (2006) 0.96
Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress. J Biol Chem (2013) 0.96
Double-stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase epsilon and of the Dpb3p-Dpb4p subassembly. Genes Cells (2003) 0.94
Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae. Genetics (2008) 0.91
The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability. Nucleic Acids Res (2012) 0.87
Why are there so many diverse replication machineries? J Mol Biol (2013) 0.86
Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae. Mutat Res (2012) 0.81