Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation.

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Published in EMBO J on October 29, 2014

Authors

Matthias Voss1, Ulrike Künzel1, Fabian Higel2, Peer-Hendrik Kuhn3, Alessio Colombo4, Akio Fukumori4, Martina Haug-Kröper1, Bärbel Klier4, Gudula Grammer1, Andreas Seidl2, Bernd Schröder5, Reinhard Obst6, Harald Steiner7, Stefan F Lichtenthaler8, Christian Haass9, Regina Fluhrer10

Author Affiliations

1: Adolf Butenandt Institute for Biochemistry, Ludwig-Maximilians University Munich, Munich, Germany.
2: Sandoz Biopharmaceuticals/HEXAL AG, Oberhaching, Germany.
3: DZNE - German Center for Neurodegenerative Diseases, Munich, Germany Institute for Advanced Study, Technische Universität München, Garching, Germany.
4: DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.
5: Biochemical Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
6: Institute for Immunology, Ludwig-Maximilians University Munich, Munich, Germany.
7: Adolf Butenandt Institute for Biochemistry, Ludwig-Maximilians University Munich, Munich, Germany DZNE - German Center for Neurodegenerative Diseases, Munich, Germany.
8: DZNE - German Center for Neurodegenerative Diseases, Munich, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany Neuroproteomics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
9: Adolf Butenandt Institute for Biochemistry, Ludwig-Maximilians University Munich, Munich, Germany DZNE - German Center for Neurodegenerative Diseases, Munich, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
10: Adolf Butenandt Institute for Biochemistry, Ludwig-Maximilians University Munich, Munich, Germany DZNE - German Center for Neurodegenerative Diseases, Munich, Germany rfluhrer@med.uni-muenchen.de.

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