Published in Exp Dermatol on February 01, 2015
Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation. Blood (2010) 1.77
Vitamin C equivalent antioxidant capacity (VCEAC) of phenolic phytochemicals. J Agric Food Chem (2002) 1.64
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Mol Cell (2012) 1.50
Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer. Clin Cancer Res (2009) 1.50
Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities. Cardiovasc Res (2008) 1.44
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Res (2008) 1.30
Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Res (2008) 1.29
CT and MRI findings of sex cord-stromal tumor of the ovary. AJR Am J Roentgenol (2005) 1.28
Tpl2 is a key mediator of arsenite-induced signal transduction. Cancer Res (2009) 1.26
Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem (2009) 1.25
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res (2008) 1.20
Resveratrol directly targets COX-2 to inhibit carcinogenesis. Mol Carcinog (2008) 1.17
Embryonic stem cell-like cells established by culture of adult ovarian cells in mice. Fertil Steril (2010) 1.15
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis (2007) 1.11
Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells. Cardiovasc Res (2009) 1.10
Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer. Cancer Res (2010) 1.07
Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis (2008) 1.07
[Two cases of metronidazole-induced encephalopathy]. Korean J Gastroenterol (2005) 1.04
Serial CT findings of Mycobacterium massiliense pulmonary disease compared with Mycobacterium abscessus disease after treatment with antibiotic therapy. Radiology (2012) 1.03
Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res (2006) 1.03
Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activity. Biochem Pharmacol (2010) 1.03
Variation in major antioxidants and total antioxidant activity of Yuzu (Citrus junos Sieb ex Tanaka) during maturation and between cultivars. J Agric Food Chem (2004) 1.03
de Quervain disease: US identification of anatomic variations in the first extensor compartment with an emphasis on subcompartmentalization. Radiology (2011) 1.01
T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. Cancer Res (2007) 1.00
Impact of myocardial infarct proteins and oscillating pressure on the differentiation of mesenchymal stem cells: effect of acute myocardial infarction on stem cell differentiation. Stem Cells (2008) 0.99
Interpreting positive signs of the supraspinatus test in screening for torn rotator cuff. Acta Med Okayama (2006) 0.98
Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol Ther (2011) 0.98
Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. Carcinogenesis (2011) 0.97
Establishment of autologous embryonic stem cells derived from preantral follicle culture and oocyte parthenogenesis. Fertil Steril (2007) 0.96
Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice. Breast Cancer Res (2011) 0.96
Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila) (2011) 0.96
Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase. Carcinogenesis (2009) 0.96
Circling mouse, a spontaneous mutant in the inner ear. Exp Anim (2002) 0.95
Hypoxic priming of mESCs accelerates vascular-lineage differentiation through HIF1-mediated inverse regulation of Oct4 and VEGF. EMBO Mol Med (2012) 0.94
Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation. J Biol Chem (2012) 0.94
Secondary sphere formation enhances the functionality of cardiac progenitor cells. Mol Ther (2012) 0.94
Protective effect of quercetin against arsenite-induced COX-2 expression by targeting PI3K in rat liver epithelial cells. J Agric Food Chem (2010) 0.94
Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin. Int J Biochem Cell Biol (2009) 0.93
Src kinase is a direct target of apigenin against UVB-induced skin inflammation. Carcinogenesis (2012) 0.93
6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. Carcinogenesis (2011) 0.93
Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells. Biopolymers (2014) 0.93
Notch inhibition promotes human embryonic stem cell-derived cardiac mesoderm differentiation. Stem Cells (2008) 0.92
Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase. J Biol Chem (2008) 0.92
A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. Mol Carcinog (2011) 0.92
H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells. Int J Cancer (2006) 0.92
Functional analysis of TiO2 nanoparticle toxicity in three plant species. Biol Trace Elem Res (2013) 0.92
Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro. Fertil Steril (2007) 0.91
Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway. J Biol Chem (2007) 0.91
Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission. J Biol Chem (2013) 0.91
Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells. Ann N Y Acad Sci (2007) 0.91
Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro. Food Chem Toxicol (2009) 0.90
Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin. Cancer Prev Res (Phila) (2013) 0.90
7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. J Biol Chem (2011) 0.90
Protective effects of piceatannol against beta-amyloid-induced neuronal cell death. Ann N Y Acad Sci (2007) 0.90
Enzymatic production of 3,6-anhydro-L-galactose from agarose and its purification and in vitro skin whitening and anti-inflammatory activities. Appl Microbiol Biotechnol (2012) 0.90
Phytotoxic effects and chemical analysis of leaf extracts from three Phytolaccaceae species in South Korea. J Chem Ecol (2005) 0.89
Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis. Ann N Y Acad Sci (2011) 0.89
High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: roles of adipocytes and M2-macrophages. Int J Cancer (2014) 0.89
Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1. Cancer Res (2010) 0.89
Eupatilin, a major flavonoid of Artemisia, attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities. Planta Med (2013) 0.89
Human feeder layer system derived from umbilical cord stromal cells for human embryonic stem cells. Fertil Steril (2010) 0.89
Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK. Mutat Res (2008) 0.89
Antioxidant activity of black tea vs. green tea. J Nutr (2002) 0.89
Jaceosidin, a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells. Ann N Y Acad Sci (2007) 0.88
Autoimmune hemolytic anemia in a patient with primary ovarian non-Hodgkin's lymphoma. J Korean Med Sci (2004) 0.88
Caffeinated coffee, decaffeinated coffee, and the phenolic phytochemical chlorogenic acid up-regulate NQO1 expression and prevent H₂O₂-induced apoptosis in primary cortical neurons. Neurochem Int (2012) 0.88
Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling. Ann N Y Acad Sci (2009) 0.88
Investigation of heavy metal accumulation in Polygonum thunbergii for phytoextraction. Environ Pollut (2003) 0.88
Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1. Biochem Pharmacol (2010) 0.88
Sonographic differentiation of benign and malignant papillary lesions of the breast. J Ultrasound Med (2008) 0.88
Fine mapping of the circling (cir) gene on the distal portion of mouse chromosome 9. Comp Med (2003) 0.88
Preventive effects of vitamin C on carcinogenesis. Lancet (2002) 0.88
5-deoxykaempferol plays a potential therapeutic role by targeting multiple signaling pathways in skin cancer. Cancer Prev Res (Phila) (2010) 0.87
Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B. Genes Nutr (2008) 0.87
7,3',4'-Trihydroxyisoflavone inhibits epidermal growth factor-induced proliferation and transformation of JB6 P+ mouse epidermal cells by suppressing cyclin-dependent kinases and phosphatidylinositol 3-kinase. J Biol Chem (2010) 0.87
Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis. Mol Ther (2013) 0.87
Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice. Am J Physiol Endocrinol Metab (2013) 0.87
Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf. Biochem Pharmacol (2010) 0.87
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol suppresses UV-Induced MMP-1 expression through AMPK-mediated mTOR inhibition as a downstream of the PKA-LKB1 pathway. J Cell Biochem (2014) 0.86
Cancer chemopreventive effects of lactic acid bacteria. J Microbiol Biotechnol (2007) 0.86
Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo. Carcinogenesis (2009) 0.86
Estradiol protects PC12 cells against CoCl2-induced apoptosis. Brain Res Bull (2008) 0.86
Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target. FEBS Lett (2005) 0.86
Human peripheral blood-born hematosphere as a niche for hematopoietic stem cell expansion. Cell Res (2011) 0.86
Cholinesterase and BACE1 inhibitory diterpenoids from Aralia cordata. Arch Pharm Res (2009) 0.86
Phosphatidylinositol 3-kinase, a novel target molecule for the inhibitory effects of kaempferol on neoplastic cell transformation. Carcinogenesis (2010) 0.86
Induction of apoptosis in a human lymphoma cell line by hydrophobic peptide fraction separated from anchovy sauce. Biofactors (2004) 0.86
Curcumin suppresses proliferation of colon cancer cells by targeting CDK2. Cancer Prev Res (Phila) (2014) 0.86
Maslinic acid inhibits the metastatic capacity of DU145 human prostate cancer cells: possible mediation via hypoxia-inducible factor-1α signalling. Br J Nutr (2012) 0.85