MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 4242830)

Published in J Cell Biol on November 24, 2014

Authors

Mohammed I Ahmed1, Majid Alam1, Vladimir U Emelianov2, Krzysztof Poterlowicz1, Ankit Patel1, Andrey A Sharov2, Andrei N Mardaryev1, Natalia V Botchkareva3

Author Affiliations

1: Centre for Skin Sciences, School of Life Sciences, University of Bradford, Bradford BD7 1DP, England, UK.
2: Department of Dermatology, Boston University, Boston, MA 02118.
3: Centre for Skin Sciences, School of Life Sciences, University of Bradford, Bradford BD7 1DP, England, UK n.botchkareva@bradford.ac.uk.

Articles cited by this

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62

The role of site accessibility in microRNA target recognition. Nat Genet (2007) 18.52

Fast and effective prediction of microRNA/target duplexes. RNA (2004) 18.10

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med (2003) 12.94

A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A (1996) 11.37

microRNAs: tiny regulators with great potential. Cell (2001) 11.23

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41

Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95

WNT signals are required for the initiation of hair follicle development. Dev Cell (2002) 6.63

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J Invest Dermatol (2001) 6.12

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell (2000) 6.08

MicroRNA control of signal transduction. Nat Rev Mol Cell Biol (2010) 5.74

A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66

Sonic hedgehog signaling is essential for hair development. Curr Biol (1998) 5.58

Controls of hair follicle cycling. Physiol Rev (2001) 5.49

Prediction of both conserved and nonconserved microRNA targets in animals. Bioinformatics (2007) 4.91

GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol (2003) 4.60

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60

Molecular mechanisms regulating hair follicle development. J Invest Dermatol (2002) 4.16

Dynamics between stem cells, niche, and progeny in the hair follicle. Cell (2011) 4.14

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol (2005) 4.04

A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet (1999) 3.93

The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol (2006) 3.64

Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol (1999) 3.62

Programming gene expression in developing epidermis. Development (1994) 3.60

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature (2010) 3.37

WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanism. Science (2006) 3.36

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J Cell Biol (2004) 3.24

Molecular principles of hair follicle induction and morphogenesis. Bioessays (2005) 3.08

miR-214 targets ATF4 to inhibit bone formation. Nat Med (2012) 3.01

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev (1995) 2.99

Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol (1999) 2.99

A comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis. J Invest Dermatol (1999) 2.92

miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ (2008) 2.86

beta-catenin activity in the dermal papilla regulates morphogenesis and regeneration of hair. Dev Cell (2010) 2.60

The hair follicle as a dynamic miniorgan. Curr Biol (2009) 2.52

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev (2003) 2.12

Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog. J Clin Invest (1999) 2.02

A family business: stem cell progeny join the niche to regulate homeostasis. Nat Rev Mol Cell Biol (2012) 1.91

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest (2011) 1.81

Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72

Twist-1 regulates the miR-199a/214 cluster during development. Nucleic Acids Res (2008) 1.71

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development (2006) 1.66

Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (2007) 1.53

Dnm3os, a non-coding RNA, is required for normal growth and skeletal development in mice. Dev Dyn (2008) 1.45

Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am J Cardiovasc Dis (2011) 1.43

Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41

Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline. Development (2013) 1.41

Molecular biology of hair morphogenesis: development and cycling. J Exp Zool B Mol Dev Evol (2003) 1.36

Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci U S A (2006) 1.35

Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell (2011) 1.33

Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol (2012) 1.32

Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell (2010) 1.31

miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro. Biochem Biophys Res Commun (2010) 1.29

Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle. FASEB J (2010) 1.21

New pancreas from old: microregulators of pancreas regeneration. Trends Endocrinol Metab (2007) 1.20

MicroRNAs and their roles in mammalian stem cells. J Cell Sci (2011) 1.19

Integrating positional information at the level of Smad1/5/8. Curr Opin Genet Dev (2008) 1.17

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis. J Invest Dermatol (2012) 1.13

MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway. Nat Cell Biol (2013) 1.11

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development (2012) 1.11

Stem cell dynamics in the hair follicle niche. Semin Cell Dev Biol (2013) 1.08

Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation. Dev Biol (2013) 1.02

MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes. J Cell Sci (2011) 1.01

MicroRNA-214 promotes myogenic differentiation by facilitating exit from mitosis via down-regulation of proto-oncogene N-ras. J Biol Chem (2010) 0.99

Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK. J Mol Med (Berl) (2012) 0.96

MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of β-catenin. Biochem Biophys Res Commun (2012) 0.95

Epidermal dysplasia and abnormal hair follicles in transgenic mice overexpressing homeobox gene MSX-2. J Invest Dermatol (1999) 0.94

Systems control of BMP morphogen flow in vertebrate embryos. Curr Opin Genet Dev (2011) 0.94

A role for p75 neurotrophin receptor in the control of hair follicle morphogenesis. Dev Biol (1999) 0.91

Chromatin regulators in mammalian epidermis. Semin Cell Dev Biol (2012) 0.91

Control by a hair's breadth: the role of microRNAs in the skin. Cell Mol Life Sci (2012) 0.90

MicroRNA/mRNA regulatory networks in the control of skin development and regeneration. Cell Cycle (2012) 0.90

Prolactin--a novel neuroendocrine regulator of human keratin expression in situ. FASEB J (2010) 0.89

Effects of in vivo transfection with anti-miR-214 on gene expression in murine molar tooth germ. Physiol Genomics (2011) 0.89

Bone morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration. J Invest Dermatol (2013) 0.89

Role of sonic hedgehog in maintaining a pool of proliferating stem cells in the human fetal epidermis. Hum Reprod (2006) 0.87

Inhibition of glycogen synthase kinase-3β suppresses inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes and collagen-induced arthritis. Joint Bone Spine (2013) 0.87

Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling. Proc Natl Acad Sci U S A (2013) 0.85

Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model. Blood (2010) 0.85