Published in Public Health Genomics on November 26, 2014
Neurogenomics: An opportunity to integrate neuroscience, genomics and bioinformatics research in Africa. Appl Transl Genom (2015) 0.90
Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. Alcohol Clin Exp Res (2015) 0.85
Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity. BMC Genomics (2016) 0.79
Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients. Cardiovasc J Afr (2015) 0.76
Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back-Looking Forward to Next-Generation Innovation. OMICS (2017) 0.75
Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs. OMICS (2017) 0.75
Cost and yield considerations when expanding recruitment for genetic studies: the primary open-angle African American glaucoma genetics study. BMC Med Res Methodol (2017) 0.75
The International HapMap Project. Nature (2003) 73.65
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature (2009) 26.47
Mutation in TET2 in myeloid cancers. N Engl J Med (2009) 16.07
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63
A whole-genome association study of major determinants for host control of HIV-1. Science (2007) 15.19
Positive natural selection in the human lineage. Science (2006) 12.55
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (2010) 9.61
A large-scale, consortium-based genomewide association study of asthma. N Engl J Med (2010) 9.17
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics (2007) 8.03
Discovery and refinement of loci associated with lipid levels. Nat Genet (2013) 7.86
Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA (2009) 6.80
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet (2009) 6.61
African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping. Annu Rev Genomics Hum Genet (2008) 6.06
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet (2009) 6.04
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood (2009) 5.72
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet (2010) 5.02
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature (2010) 4.64
New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet (2008) 4.35
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
A genome-wide association study of hypertension and blood pressure in African Americans. PLoS Genet (2009) 4.28
Genetic analysis of African populations: human evolution and complex disease. Nat Rev Genet (2002) 4.23
Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. J Am Med Inform Assoc (2011) 4.20
Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18
FMR1 and the fragile X syndrome: human genome epidemiology review. Genet Med (2001) 3.84
CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal (2009) 3.77
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry (2009) 3.64
Genomic medicine--an updated primer. N Engl J Med (2010) 3.48
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet (2008) 3.37
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet (2002) 3.32
Two newly identified genetic determinants of pigmentation in Europeans. Nat Genet (2008) 3.31
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet (2013) 3.21
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07
Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05
Genetic associations with valvular calcification and aortic stenosis. N Engl J Med (2013) 3.02
Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99
A comprehensive family-based replication study of schizophrenia genes. JAMA Psychiatry (2013) 2.93
A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc Natl Acad Sci U S A (2006) 2.91
Host determinants of HIV-1 control in African Americans. J Infect Dis (2010) 2.90
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. Hypertension (2012) 2.86
Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat Genet (2010) 2.73
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
Genome-wide association study identifies candidate genes for male fertility traits in humans. Am J Hum Genet (2012) 2.56
Next generation disparities in human genomics: concerns and remedies. Trends Genet (2009) 2.53
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Blood (2009) 2.50
Heritability of malaria in Africa. PLoS Med (2005) 2.49
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nat Genet (2010) 2.48
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. J Appl Physiol (1985) (2010) 2.43
Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res (2002) 2.29
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet (2011) 2.26
Ethical data release in genome-wide association studies in developing countries. PLoS Med (2009) 2.23
A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. Kidney Int (2010) 2.22
Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol (2009) 2.20
Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet (2009) 2.14
Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line. Int J Cancer (2008) 2.11
HLA class II locus and susceptibility to podoconiosis. N Engl J Med (2012) 2.08
Genetics of human social behavior. Neuron (2010) 2.07
Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome. Blood (2010) 2.05
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Ethical issues in human genomics research in developing countries. BMC Med Ethics (2011) 2.02
Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network. Hum Genet (2011) 2.00
A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney Int (2010) 1.98
Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry (2013) 1.98
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Nat Genet (2010) 1.97
Genome-wide association of anthropometric traits in African- and African-derived populations. Hum Mol Genet (2010) 1.90
The gift of Gab. FEBS Lett (2002) 1.90
Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. Genome Res (2010) 1.87
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet (2010) 1.83
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst (2013) 1.81
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet (2011) 1.77
The A's, G's, C's, and T's of health disparities. BMC Med Genomics (2009) 1.75
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. Nat Genet (2012) 1.74
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Ancestry and disease in the age of genomic medicine. N Engl J Med (2010) 1.71
Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic. Hypertension (2008) 1.66
Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. J Hepatol (2011) 1.59
Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry (2012) 1.57
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. PLoS Genet (2011) 1.57
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans. Nephrol Dial Transplant (2013) 1.56
A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. Mol Psychiatry (2012) 1.55
Seeking consent to genetic and genomic research in a rural Ghanaian setting: a qualitative study of the MalariaGEN experience. BMC Med Ethics (2012) 1.55
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling. Genome Biol (2008) 3.93
Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J Cereb Blood Flow Metab (2009) 2.85
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. J Cereb Blood Flow Metab (2006) 2.20
Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood. BMC Med Genomics (2009) 1.73
Gene expression profiling of blood for the prediction of ischemic stroke. Stroke (2010) 1.61
Signatures of cardioembolic and large-vessel ischemic stroke. Ann Neurol (2010) 1.50
Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling. Genes Dev (2004) 1.46
Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome. Genomics (2006) 1.39
Hypoxia preconditioning in the brain. Dev Neurosci (2005) 1.30
Blood-brain barrier breakdown and repair by Src after thrombin-induced injury. Ann Neurol (2010) 1.26
The future of genomic profiling of neurological diseases using blood. Arch Neurol (2006) 1.24
Profiles of lacunar and nonlacunar stroke. Ann Neurol (2011) 1.19
UGT1A1 is a major locus influencing bilirubin levels in African Americans. Eur J Hum Genet (2011) 1.14
Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons. Neurobiol Dis (2008) 1.05
Plasmodium falciparum gametocyte development 1 (Pfgdv1) and gametocytogenesis early gene identification and commitment to sexual development. PLoS Pathog (2012) 1.05
Characterization of the mitochondrial inner membrane protein translocator Tim17 from Trypanosoma brucei. Mol Biochem Parasitol (2008) 1.04
MeCP2 modulates gene expression pathways in astrocytes. Mol Autism (2013) 1.03
Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral blood. J Cereb Blood Flow Metab (2009) 1.02
Genomics of brain and blood: progress and pitfalls. Epilepsia (2006) 0.91
Genomic profiles of stroke in blood. Stroke (2007) 0.90
Gene expression profiling of blood in brain arteriovenous malformation patients. Transl Stroke Res (2011) 0.90
Genome response to tissue plasminogen activator in experimental ischemic stroke. BMC Genomics (2010) 0.89
GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study. Brain Res (2011) 0.87
Regional differences in awareness and attitudes regarding genetic testing for disease risk and ancestry. Hum Genet (2010) 0.87
Ten years of podoconiosis research in Ethiopia. PLoS Negl Trop Dis (2013) 0.87
Podoconiosis patients' willingness to pay for treatment services in Northwest Ethiopia: potential for cost recovery. BMC Public Health (2014) 0.86
Personal DNA testing in college classrooms: perspectives of students and professors. Genet Test Mol Biomarkers (2013) 0.85
Tilting at windmills no longer: a data-driven discussion of DTC DNA ancestry tests. Genet Med (2012) 0.85
Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls. Gend Med (2012) 0.82
The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach. Biol Psychol (2012) 0.81
Distinctive RNA expression profiles in blood associated with Alzheimer disease after accounting for white matter hyperintensities. Alzheimer Dis Assoc Disord (2014) 0.77
A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis. Mol Cell Neurosci (2007) 0.76
DNA repair/replication transcripts are down regulated in patients with Fragile X Syndrome. BMC Res Notes (2013) 0.75
Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry. J Hypertens (2017) 0.75
Clinical and sociodemographic factors predict coping styles among adults with sickle cell disease. J Natl Med Assoc (2010) 0.75
Genomics of Cardiometabolic Disorders in Sub-Saharan Africa. Public Health Genomics (2017) 0.75