Safety and effectiveness of dipeptidyl peptidase-4 inhibitors versus intermediate-acting insulin or placebo for patients with type 2 diabetes failing two oral antihyperglycaemic agents: a systematic review and network meta-analysis.

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🔗 View Article (PMC 4275675)

Published in BMJ Open on December 23, 2014

Authors

Andrea C Tricco1, Jesmin Antony1, Paul A Khan1, Marco Ghassemi1, Jemila S Hamid2, Huda Ashoor1, Erik Blondal1, Charlene Soobiah1, Catherine H Yu1, Brian Hutton3, Brenda R Hemmelgarn4, David Moher3, Sumit R Majumdar5, Sharon E Straus6

Author Affiliations

1: Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
2: Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
3: Clinical Epidemiology Program, Ottawa Hospital Research Institute and the Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
4: Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
5: Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
6: Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada Department of Geriatric Medicine, University of Toronto, Toronto, Ontario, Canada.

Associated clinical trials:

Saxagliptin Triple Oral Therapy | NCT01128153

Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone | NCT00996658

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