Published in J Invest Dermatol on February 10, 2015
Endocannabinoid system as a regulator of tumor cell malignancy - biological pathways and clinical significance. Onco Targets Ther (2016) 1.14
Anticancer mechanisms of cannabinoids. Curr Oncol (2016) 0.86
The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids. J Neuroimmune Pharmacol (2015) 0.79
Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate. Front Oncol (2017) 0.77
A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion. Mol Cancer Ther (2015) 0.76
Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells. Curr Genomics (2017) 0.75
Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents. Front Pharmacol (2016) 0.75
Prognostic Impact of Autophagy Biomarkers for Cutaneous Melanoma. Front Oncol (2016) 0.75
Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro. Acta Pharmacol Sin (2016) 0.75
Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration. Oncotarget (2016) 0.75
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy (2016) 0.75
Autophagy activation protects shock wave induced renal tubular epithelial cell apoptosis may through modulation of Akt/ GSK-3β pathway. Int J Biol Sci (2016) 0.75
Endocannabinoids as Guardians of Metastasis. Int J Mol Sci (2016) 0.75
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy (2007) 11.74
Autophagy in human health and disease. N Engl J Med (2013) 8.71
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol (2009) 8.68
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev (2002) 8.50
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer (2012) 6.14
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science (2011) 5.62
CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma. Clin Cancer Res (2012) 4.56
The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther (2011) 4.39
p53 status determines the role of autophagy in pancreatic tumour development. Nature (2013) 4.31
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol (2013) 3.88
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem (2006) 3.74
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest (2009) 3.23
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. Br J Pharmacol (2007) 3.16
Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist (2011) 2.89
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ (2008) 2.89
Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy. J Invest Dermatol (2010) 2.18
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Autophagy (2012) 1.86
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell (2006) 1.85
Autophagic cell death: Loch Ness monster or endangered species? Autophagy (2011) 1.82
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms. Cell Death Dis (2011) 1.76
Autophagy guards against cisplatin-induced acute kidney injury. Am J Pathol (2012) 1.56
Beclin 1-independent autophagy contributes to apoptosis in cortical neurons. Autophagy (2011) 1.42
Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes. Cell Death Differ (2013) 1.42
Towards the use of cannabinoids as antitumour agents. Nat Rev Cancer (2012) 1.41
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther (2011) 1.30
Cannabinoid receptors as novel targets for the treatment of melanoma. FASEB J (2006) 1.25
A combined preclinical therapy of cannabinoids and temozolomide against glioma. Mol Cancer Ther (2011) 1.17
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma. Br J Cancer (2009) 1.13
Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours. Apoptosis (2007) 1.08
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin Cancer Res (2011) 1.05
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cell Mol Life Sci (2006) 1.04
Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma. Clin Cancer Res (2009) 1.01
Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications. Semin Cancer Biol (2013) 0.97
The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action. Biochim Biophys Acta (2013) 0.91
Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. Br J Cancer (2005) 0.90
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action. Autophagy (2009) 0.86
Targeted therapy resistance mechanisms and therapeutic implications in melanoma. Hematol Oncol Clin North Am (2014) 0.85
Stress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3. PLoS One (2012) 0.83