Published in J Physiol on March 01, 1985
Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors. J Neurosci (1997) 2.51
'Concentration-clamp' study of gamma-aminobutyric-acid-induced chloride current kinetics in frog sensory neurones. J Physiol (1986) 1.80
Modulation of GABA(A) receptor channel gating by pentobarbital. J Physiol (2001) 1.74
Gramicidin-perforated patch recording: GABA response in mammalian neurones with intact intracellular chloride. J Physiol (1995) 1.69
Sodium currents in dissociated bull-frog sympathetic neurones. J Physiol (1987) 1.55
Kinetic properties of the pentobarbitone-gated chloride current in frog sensory neurones. J Physiol (1987) 1.43
Contribution of chloride shifts to the fade of gamma-aminobutyric acid-gated currents in frog dorsal root ganglion cells. J Physiol (1987) 1.35
Potentiation of gamma-aminobutyric-acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurones. J Physiol (1987) 1.34
Enhancement of gamma-aminobutyric acid-activated Cl- currents in cultured rat hippocampal neurones by three volatile anaesthetics. J Physiol (1992) 1.33
Activation and block of recombinant GABA(A) receptors by pentobarbitone: a single-channel study. Br J Pharmacol (2000) 1.19
Blocking effects of cobalt and related ions on the gamma-aminobutyric acid-induced current in turtle retinal cones. J Physiol (1986) 1.16
Actions of gamma-aminobutyric acid on rat supraoptic nucleus neurosecretory neurones in vitro. J Physiol (1987) 1.08
Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA. Biophys J (2009) 1.07
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones. Br J Pharmacol (1989) 1.06
Amygdala inputs drive feedforward inhibition in the medial prefrontal cortex. J Neurophysiol (2013) 1.04
Closing the gate in the limbic striatum: prefrontal suppression of hippocampal and thalamic inputs. Neuron (2013) 1.03
Characteristics of GABA-activated chloride channels in mammalian dorsal root ganglion neurones. J Physiol (1989) 0.95
Allosteric modulation of an expressed homo-oligomeric GABA-gated chloride channel of Drosophila melanogaster. Br J Pharmacol (1996) 0.93
Bradykinin decreases K(+) and increases Cl(-) conductances in vagal afferent neurones of the guinea pig. J Physiol (2004) 0.92
Trichloroethanol potentiation of gamma-aminobutyric acid-activated chloride current in mouse hippocampal neurones. Br J Pharmacol (1994) 0.91
Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurones. Br J Pharmacol (1989) 0.87
Potentiation by sevoflurane of the gamma-aminobutyric acid-induced chloride current in acutely dissociated CA1 pyramidal neurones from rat hippocampus. Br J Pharmacol (1996) 0.86
Pentobarbital produces activation and block of {alpha}1{beta}2{gamma}2S GABAA receptors in rapidly perfused whole cells and membrane patches: divergent results can be explained by pharmacokinetics. J Gen Physiol (2009) 0.85
Sodium-dependent suppression of gamma-aminobutyric-acid-gated chloride currents in internally perfused frog sensory neurones. J Physiol (1987) 0.85
Allosteric modulators affect the efficacy of partial agonists for recombinant GABA(A) receptors. Br J Pharmacol (2000) 0.84
Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats. J Physiol (2003) 0.82
Enhanced desensitization followed by unusual resensitization in GABAA receptors in phospholipase C-related catalytically inactive protein-1/2 double-knockout mice. Pflugers Arch (2014) 0.80
Non-competitive inhibition of GABAA responses by a new class of quinolones and non-steroidal anti-inflammatories in dissociated frog sensory neurones. Br J Pharmacol (1992) 0.79
Effects of diuretics on GABA-gated chloride current in frog isolated sensory neurones. Br J Pharmacol (1988) 0.79
Stereoselective interaction of thiopentone enantiomers with the GABA(A) receptor. Br J Pharmacol (1999) 0.79
Kinetic and pharmacological properties of the GABA-induced chloride current in Aplysia neurones: a 'concentration clamp' study. Br J Pharmacol (1988) 0.76
The uptake of [3H]GABA by slices of rat cerebral cortex. J Neurochem (1968) 5.05
PHARMACOLOGICAL STUDIES ON PRESYNAPTIC INHIBITION. J Physiol (1963) 3.90
Actions of gamma-aminobutyric acid on sympathetic ganglion cells. J Physiol (1975) 3.60
Effect of internal fluoride and phosphate on membrane currents during intracellular dialysis of nerve cells. Nature (1975) 3.18
A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. J Physiol (1969) 2.72
Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid. J Physiol (1980) 2.59
Characterization and ionic basis of GABA-induced depolarizations recorded in vitro from cat primary afferent neurones. J Physiol (1978) 2.46
Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro. J Physiol (1982) 2.39
Effects of internal free calcium upon the sodium and calcium channels in the tunicate egg analysed by the internal perfusion technique. J Physiol (1978) 2.05
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. J Neurochem (1971) 2.00
GABA-mediated biphasic inhibitory responses in hippocampus. Nature (1979) 1.97
Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture. J Physiol (1978) 1.84
Inhibition of GABA uptake in rat brain slices by nipecotic acid, various isoxazoles and related compounds. J Neurochem (1975) 1.67
PHARMACOLOGICAL STUDIES ON THE PRIMARY AFFERENT DEPOLARIZATION OF THE TOAD SPINAL CORD. Pflugers Arch Gesamte Physiol Menschen Tiere (1963) 1.55
Separation of ionic currents in the somatic membrane of frog sensory neurons. J Membr Biol (1984) 1.52
Analysis of amino acid responses on frog motoneurones. Neuropharmacology (1976) 1.47
The effects of pentobarbital and related compounds on frog motoneurons. Brain Res (1980) 1.41
Influence of neuroglial transport on the action of gamma-aminobutyric acid on mammalian ganglion cells. Br J Pharmacol (1977) 1.40
Presynaptic action of barbiturates in the frog spinal cord. Proc Natl Acad Sci U S A (1975) 1.38
A model for the mode of action of GABA on primary afferent terminals: depolarizing effects of GABA applied iontophoretically to neurones of mammalian dorsal root ganglia. Neuropharmacology (1974) 1.31
Depolarization of neurones in the isolated olfactory cortex of the guinea-pig by gamma-aminobutyric acid. Br J Pharmacol (1979) 1.29
(-)Pentobarbital opens ion channels of long duration in cultured mouse spinal neurons. Science (1980) 1.26
Internal perfusion studies demonstrating GABA-induced chloride responses in frog primary afferent neurons. Am J Physiol (1984) 1.25
gamma-Aminobutyric acid agonists: an in vitro comparison between depression of spinal synaptic activity and depolarization of spinal root fibres in the rat. Br J Pharmacol (1980) 1.23
The role of GABA in primary afferent depolarization. Prog Neurobiol (1977) 1.21
Competitive interaction of beta-guanidino propionic acid and gamma-aminobutyric acid on the muscle fibre of the crayfish. J Physiol (1971) 1.20
Potentiation of the effects of GABA by pentobarbitone. Brain Res (1979) 1.20
Chloride-dependent enhancement by barbiturates of gamma-aminobutyric acid receptor binding. J Neurosci (1982) 1.15
Enhancement of GABA binding by pentobarbitone. Neurosci Lett (1980) 1.14
Chlordiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture. J Neurophysiol (1981) 1.12
Werman R:The cooperativity of -aminobutyric action on the membrane of locust muscle fibers. Mol Pharmacol (1973) 1.11
Excitatory and inhibitory actions of GABA and glycine on embryonic chick spinal neurons in culture. Brain Res (1978) 1.11
Reversal of the action of amino acid antagonists by barbiturates and other hypnotic drugs. Br J Pharmacol (1978) 1.10
Increase in permeability of the postsynaptic membrane to potassium produced by 'nembutal'. Nature (1967) 1.05
Conductance increases produced by glycine and gamma-aminobutyric acid in lamprey interneurones. J Physiol (1978) 1.04
Biphasic response of hippocampal pyramidal neurons to GABA. Neurosci Lett (1981) 1.01
Effect of barbiturates on the GABA receptor of cat primary afferent neurones. J Physiol (1982) 1.01
Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones. J Physiol (1981) 0.95
Accelerating effects of pentobarbitone on the inactivation process of the calcium current in Helix neurones. Br J Pharmacol (1983) 0.95
A comparison of the effects of pentobarbital and diphenylhydantoin on the GABA sensitivity and excitability of adult sensory ganglion cells. Brain Res (1981) 0.92
Inhibitory effects of propranolol on the calcium current of Helix neurones. Br J Pharmacol (1981) 0.87
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines. Neuropharmacology (1979) 0.86
Action of pentobarbital on sympathetic ganglion cells. J Neurophysiol (1978) 0.86
Dual action of pentobarbitone on GABA binding: role of binding site integrity. J Neurochem (1981) 0.85
Depolarizing postsynaptic actions of GABA in the rat dentate gyrus. Adv Biochem Psychopharmacol (1981) 0.85
Zinc current in Helix soma membrane. Comp Biochem Physiol C (1982) 0.83
[Narcotic effectiveness and tissue distribution of the optical antipodes of the pentobarbitals in the rat]. Biochem Pharmacol (1969) 0.81
A calcium reversible action of barbiturates on the leech Retzius cell. J Pharmacol Exp Ther (1977) 0.80
Pentobarbitone slows the dissociation of GABA from rat brain synaptosomal binding sites. Neurosci Lett (1981) 0.78
Anesthetic and lethal activity in mice of the stereoisomers of 5-ethyl-5-(1-methylbutyl)barbituric acid (pentobarbital). Arch Int Pharmacodyn Ther (1973) 0.78
Barbiturate-induced slow outward currents in Aplysia neurones. Nature (1978) 0.77
Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature (1995) 10.89
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med (2001) 9.53
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell (1988) 7.76
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature (1988) 7.45
The calcium current of Helix neuron. J Gen Physiol (1978) 5.18
Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans. Neuron (1996) 3.58
Properties of internally perfused, voltage-clamped, isolated nerve cell bodies. J Gen Physiol (1978) 3.44
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. EMBO J (1999) 3.42
Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells. Circ Res (2001) 3.30
Electric and magnetic phenomena observed before the volcano-seismic activity in 2000 in the Izu Island Region, Japan. Proc Natl Acad Sci U S A (2002) 3.18
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J Immunol (1996) 2.80
Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex. Mol Cell Biol (1990) 2.73
Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. Neuroscience (2002) 2.47
Ghrelin stimulates gastric acid secretion and motility in rats. Biochem Biophys Res Commun (2000) 2.42
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J Biol Chem (2001) 2.29
Sodium current in single heart muscle cells. Nature (1979) 2.19
p.E66Q mutation in the GLA gene is associated with a high risk of cerebral small-vessel occlusion in elderly Japanese males. Eur J Neurol (2013) 2.11
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest (2000) 2.08
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc Natl Acad Sci U S A (1999) 2.04
Mitochondrial mutation in fatal infantile cardiomyopathy. Lancet (1990) 1.98
Endoscopic pancreatocholangiography. II. The pathological endoscopic pancreatocholangiogram. Gastroenterology (1972) 1.96
Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci U S A (2001) 1.90
Molecular cloning and expression of megakaryocyte potentiating factor cDNA. J Biol Chem (1995) 1.88
Clinical outcome after radiofrequency catheter ablation of focal atrial fibrillation triggers. J Cardiovasc Electrophysiol (2001) 1.83
Glucose and osmosensitive neurones of the rat hypothalamus. Nature (1969) 1.83
'Concentration-clamp' study of gamma-aminobutyric-acid-induced chloride current kinetics in frog sensory neurones. J Physiol (1986) 1.80
The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription. Oncogene (1989) 1.78
The units of calcium conduction in Helix neurones. Nature (1978) 1.78
Factor XI contributes to thrombus propagation on injured neointima of the rabbit iliac artery. J Thromb Haemost (2006) 1.74
Patients with idiopathic cardiomyopathy belong to the same mitochondrial DNA gene family of Parkinson's disease and mitochondrial encephalomyopathy. Biochem Biophys Res Commun (1991) 1.70
Gramicidin-perforated patch recording: GABA response in mammalian neurones with intact intracellular chloride. J Physiol (1995) 1.69
Endoscopic pancreatocholangiography. I. The normal endoscopic pancreatocholangiogram. Gastroenterology (1972) 1.68
Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1. Ann N Y Acad Sci (2001) 1.67
Reduced elimination of IgG antibodies by engineering the variable region. Protein Eng Des Sel (2010) 1.64
The suction pipette method for internal perfusion and voltage clamp of small excitable cells. J Neurosci Methods (1980) 1.64
Trypsin inhibits the action of tetrodotoxin on neurones. Nature (1977) 1.61
Regulation of intracellular chloride by cotransporters in developing lateral superior olive neurons. J Neurosci (1999) 1.56
Neointimal formation at the sites of anastomosis of the internal thoracic artery grafts after coronary artery bypass grafting in human subjects: an immunohistochemical analysis. J Thorac Cardiovasc Surg (2000) 1.54
Separation of ionic currents in the somatic membrane of frog sensory neurons. J Membr Biol (1984) 1.52
Modeling, synthesis and biological activity of novel antifungal agents (1). Bioorg Med Chem Lett (1998) 1.52
A novel cytokine exhibiting megakaryocyte potentiating activity from a human pancreatic tumor cell line HPC-Y5. J Biol Chem (1994) 1.51
Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. Am J Pathol (2001) 1.48
A novel mutation causing complete deficiency of thyroxine binding globulin. Clin Endocrinol (Oxf) (1997) 1.48
Serotonin suppresses N-methyl-D-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat. Brain Res (1990) 1.47
Intracellular calcium ions decrease the affinity of the GABA receptor. Nature (1986) 1.46
Anagrelide metabolite induces thrombocytopenia in mice by inhibiting megakaryocyte maturation without inducing platelet aggregation. Exp Hematol (2001) 1.45
Progressive determination during formation of the anteroposterior axis in Xenopus laevis. Cell (1989) 1.41
Evaluation of nucleolar organizer regions in human bladder cancers by light- and electron-microscopic morphometry. Eur Urol (1998) 1.40
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits. J Pharmacol Exp Ther (1971) 1.39
Cyclic AMP modulates Ca-activated K channel in cultured smooth muscle cells of rat aortas. Am J Physiol (1988) 1.37
Bicuculline and picrotoxin block gamma-aminobutyric acid-gated Cl- conductance by different mechanisms. Experientia (1985) 1.37
Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. J Clin Invest (1998) 1.37
Contribution of chloride shifts to the fade of gamma-aminobutyric acid-gated currents in frog dorsal root ganglion cells. J Physiol (1987) 1.35
Orexin-A (Hypocretin-1) and leptin enhance LTP in the dentate gyrus of rats in vivo. Peptides (2004) 1.34
Protective effect of human granulocyte colony-stimulating factor on microbial infection in neutropenic mice. Infect Immun (1987) 1.31
ATP-induced current in isolated outer hair cells of guinea pig cochlea. J Neurophysiol (1990) 1.31
Fatal interstitial pulmonary disease in a patient with dyskeratosis congenita after allogeneic bone marrow transplantation. Bone Marrow Transplant (1997) 1.29
Social stress exacerbates stroke outcome by suppressing Bcl-2 expression. Proc Natl Acad Sci U S A (2001) 1.29
The effect of cold storage on the adrenergic mechanisms of intestinal smooth muscle. Br J Pharmacol (1972) 1.27
Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood (2000) 1.26
Tumor necrosis factor and interleukin-1 beta: suppression of food intake by direct action in the central nervous system. Brain Res (1988) 1.26
Mechanical and enzymatic isolation of mammalian CNS neurons. Neurosci Res (1988) 1.25
Internal perfusion studies demonstrating GABA-induced chloride responses in frog primary afferent neurons. Am J Physiol (1984) 1.25
Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus. Nature (1974) 1.25
Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice. Brain Res (1982) 1.24
Interleukin-6 functions as an autocrine growth factor in human bladder carcinoma cell lines in vitro. Int J Cancer (1997) 1.23
Nitroarginine inhibits endothelium-derived relaxation. Jpn J Pharmacol (1990) 1.23
The effects of noradrenaline on neurones in the rat dorsal motor nucleus of the vagus, in vitro. J Physiol (1987) 1.23
AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia. J Neurosci (2000) 1.23
Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem Biophys Res Commun (1992) 1.22
Electrophysiological properties and glucose responsiveness of guinea-pig ventromedial hypothalamic neurones in vitro. J Physiol (1986) 1.21
Functional reconstitution of a heteromeric cyclic nucleotide-gated channel of Caenorhabditis elegans in cultured cells. Brain Res (1999) 1.21
Facilitatory effect of docosahexaenoic acid on N-methyl-D-aspartate response in pyramidal neurones of rat cerebral cortex. J Physiol (1994) 1.21
Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat. J Neurophysiol (1991) 1.20
Polymicrobial sepsis following endoscopic retrograde cholangiopancreatography. Gastroenterology (1975) 1.19
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte. J Biol Chem (1993) 1.19
Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors. Gene Ther (2002) 1.19
Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat. J Neurochem (1999) 1.18
Protection against oxidative stress-induced cell death by intracellular platelet-activating factor-acetylhydrolase II. J Biol Chem (1997) 1.18
Blockade of gamma-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin. Neurosci Res (1988) 1.17
Induction of neutrophilic granulocytosis in mice by administration of purified human native granulocyte colony-stimulating factor (G-CSF). Biochem Biophys Res Commun (1987) 1.17
Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances. Neurosci Lett (1989) 1.17
Characterization of XET-related genes of rice. Plant Physiol (2000) 1.17
Mechanism of the rapid effect of 17 beta-estradiol on medial amygdala neurons. Science (1986) 1.15
Antagonists of GABA responses, studied using internally perfused frog dorsal root ganglion neurons. Neuroscience (1987) 1.15
Glucose responding neurons in the nucleus tractus solitarius of the rat: in vitro study. Brain Res (1984) 1.15
Prostaglandin D2, a cerebral sleep-inducing substance in monkeys. Proc Natl Acad Sci U S A (1988) 1.12
Cytoplasmic Ca2+ oscillation in rat megakaryocytes evoked by a novel type of purinoceptor. J Physiol (1993) 1.12
Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence. Biochem Biophys Res Commun (1990) 1.12
O-linked sugar chain of human granulocyte colony-stimulating factor protects it against polymerization and denaturation allowing it to retain its biological activity. J Biol Chem (1990) 1.12
Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1. J Biol Chem (1999) 1.11
GABA activates different types of chloride-conducting receptor-ionophore complexes in a dose-dependent manner. Brain Res (1985) 1.11