Published in Am J Hum Genet on March 26, 2015
Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci. PLoS One (2016) 0.86
Revisited HLA and non-HLA genetics of Takayasu arteritis-where are we? J Hum Genet (2015) 0.78
PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis. RMD Open (2016) 0.78
Identification of functional and expression polymorphisms associated with risk for anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Arthritis Rheumatol (2016) 0.77
Efficacy of first-line tocilizumab therapy in early polymyalgia rheumatica: a prospective longitudinal study. Ann Rheum Dis (2016) 0.76
Two Subsets of Large Vessel Vasculitis Characterized by the Absence or Presence of Spondyloarthritis or its Associated Diseases. Open Rheumatol J (2016) 0.75
Association of HLA-DRB1 amino acid residues with giant cell arteritis: genetic association study, meta-analysis and geo-epidemiological investigation. Arthritis Res Ther (2015) 0.75
Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy. Sci Rep (2017) 0.75
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. Am J Hum Genet (2016) 0.75
A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis. Sci Rep (2017) 0.75
Visual loss and other cranial ischaemic complications in giant cell arteritis. Nat Rev Rheumatol (2017) 0.75
Giant cell arteritis: ophthalmic manifestations of a systemic disease. Graefes Arch Clin Exp Ophthalmol (2016) 0.75
Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases. World J Gastroenterol (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09
A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet (2009) 17.80
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet (2006) 17.36
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet (2004) 13.71
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum (2013) 11.18
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature (1993) 8.75
The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum (1990) 8.23
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature (2013) 6.57
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet (2011) 6.36
Gene map of the extended human MHC. Nat Rev Genet (2004) 6.01
NF-kappaB and the immune response. Oncogene (2006) 5.62
Promise and pitfalls of the Immunochip. Arthritis Res Ther (2011) 5.38
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet (2012) 5.11
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet (2012) 4.46
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet (2012) 4.13
HLA and AIDS: a cautionary tale. Trends Mol Med (2001) 3.51
Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis. Arthritis Rheum (2012) 3.38
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet (2009) 3.36
Imputing amino acid polymorphisms in human leukocyte antigens. PLoS One (2013) 3.07
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet (2013) 2.87
Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet (2013) 2.85
Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet (2013) 2.60
The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness. Nat Genet (2011) 2.48
Permanent visual loss and cerebrovascular accidents in giant cell arteritis: predictors and response to treatment. Arthritis Rheum (1998) 2.28
Statistical power and significance testing in large-scale genetic studies. Nat Rev Genet (2014) 2.25
Overview of the MHC fine mapping data. Diabetes Obes Metab (2009) 2.24
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. J Allergy Clin Immunol (2011) 2.24
Genetics and epigenetics of rheumatoid arthritis. Nat Rev Rheumatol (2013) 2.20
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A (2009) 2.06
Evaluating the effective numbers of independent tests and significant p-value thresholds in commercial genotyping arrays and public imputation reference datasets. Hum Genet (2011) 1.93
c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription. J Exp Med (2001) 1.92
A common variant on chromosome 11q13 is associated with atopic dermatitis. Nat Genet (2009) 1.91
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. Nat Genet (2012) 1.85
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet (2013) 1.83
Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS One (2008) 1.73
Epidemiology of giant cell arteritis and polymyalgia rheumatica. Arthritis Rheum (2009) 1.70
Seven newly identified loci for autoimmune thyroid disease. Hum Mol Genet (2012) 1.57
ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet (2013) 1.55
Relation between HLA DRB1 alleles and corticosteroid resistance in giant cell arteritis. Ann Rheum Dis (1998) 1.51
A proximal kappaB site in the IL-23 p19 promoter is responsible for RelA- and c-Rel-dependent transcription. J Immunol (2007) 1.49
Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis. J Rheumatol (2002) 1.48
Immune mechanisms in medium and large-vessel vasculitis. Nat Rev Rheumatol (2013) 1.48
Visual manifestations of giant cell arteritis. Trends and clinical spectrum in 161 patients. Medicine (Baltimore) (2000) 1.35
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet (2014) 1.33
Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. Hum Mol Genet (2012) 1.32
The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. J Cell Physiol (2007) 1.29
HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis, and rheumatoid arthritis. Arthritis Rheum (1994) 1.23
The HLA-DRB1 locus as a genetic component in giant cell arteritis. Mapping of a disease-linked sequence motif to the antigen binding site of the HLA-DR molecule. J Clin Invest (1992) 1.23
Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease. Annu Rev Immunol (2013) 1.13
Becoming self-aware: the thymic education of regulatory T cells. Curr Opin Immunol (2010) 1.12
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet (2013) 1.11
A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. Ann Rheum Dis (2014) 1.10
Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity. Proc Natl Acad Sci U S A (2014) 1.07
Identification of multiple genetic susceptibility loci in Takayasu arteritis. Am J Hum Genet (2013) 1.03
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am J Hum Genet (2012) 1.02
Amino acid position 11 of HLA-DRβ1 is a major determinant of chromosome 6p association with ulcerative colitis. Genes Immun (2011) 1.01
Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica. Semin Arthritis Rheum (2003) 1.00
Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis. Ann Rheum Dis (2013) 0.98
Increased IL-17A expression in temporal artery lesions is a predictor of sustained response to glucocorticoid treatment in patients with giant-cell arteritis. Ann Rheum Dis (2012) 0.95
Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32). BMC Biochem (2011) 0.95
Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype. Acta Crystallogr D Biol Crystallogr (2006) 0.94
Mapping of immune-mediated disease genes. Annu Rev Genomics Hum Genet (2013) 0.93
Pathogenesis of giant cell arteritis: More than just an inflammatory condition? Autoimmun Rev (2010) 0.92
Giant cell arteritis and polymyalgia rheumatica can be differentiated by distinct patterns of HLA class II association. J Rheumatol (1998) 0.91
Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule. J Biol Chem (2012) 0.88
Genetic component of giant cell arteritis. Rheumatology (Oxford) (2013) 0.86
Polymyalgia rheumatica: a syndrome associated with HLA-DR4 antigen. Arthritis Rheum (1988) 0.86
Giant cell arteritis: epidemiology, diagnosis, and management. Curr Rheumatol Rep (2010) 0.85
HLA dosage effect in narcolepsy with cataplexy. Immunogenetics (2014) 0.85
Position 45 influences the peptide binding motif of HLA-B*44:08. Immunogenetics (2011) 0.80
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature (2014) 1.35
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet (2014) 1.33
Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes. Am J Hum Genet (2014) 1.26
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. Nat Commun (2017) 0.83
Haplotype synthesis analysis reveals functional variants underlying known genome-wide associated susceptibility loci. Bioinformatics (2016) 0.76
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. Am J Hum Genet (2016) 0.75
LILRA3 deficiency is not involved in the giant cell arteritis and systemic sclerosis predisposition. Clin Exp Rheumatol (2016) 0.75