Epidemiology and pathophysiology of Takotsubo syndrome.

PubWeight™: 1.66‹?› | Rank: Top 3%

🔗 View Article (PMID 25855605)

Published in Nat Rev Cardiol on April 07, 2015

Authors

Yoshihiro J Akashi1, Holger M Nef2, Alexander R Lyon3

Author Affiliations

1: Division of Cardiology, Department of Internal Medicine, St Marianna University School of Medicine, 2-16-1 Sugao Miyamae-ku, Kawasaki City, Kanagawa 216-8511, Japan.
2: Medizinische Klinik I, Kardiologie und Angiologie, Universitätsklinikum Gießen, Rudolf-Buchheim-Straße 8, Gießen 35392, Germany.
3: NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and Imperial College, Sydney Street, London SW3 6NP, UK.

Articles citing this

Trends in Short- and Long-Term Outcomes for Takotsubo Cardiomyopathy Among Medicare Fee-for-Service Beneficiaries, 2007 to 2012. JACC Heart Fail (2015) 1.53

Important role of myocardial tissue characterization by cardiac MRI in diagnosing Takotsubo syndrome. Nat Rev Cardiol (2015) 0.84

Takotsubo cardiomyopathy and microcirculatory dysfunction. Nat Rev Cardiol (2015) 0.84

Autonomic nervous system and a 'vascular phase' in Takotsubo syndrome pathogenesis. Nat Rev Cardiol (2015) 0.84

Delayed-Type Hypersensitivity to Metals of Environmental Burden in Patients with Takotsubo Syndrome - Is There a Clinical Relevance? PLoS One (2016) 0.75

Takotsubo syndrome: Advances in the understanding and management of an enigmatic stress cardiomyopathy. World J Cardiol (2016) 0.75

Neuroticism, depression and anxiety in takotsubo cardiomyopathy. BMC Cardiovasc Disord (2016) 0.75

Incidence and predictors of stroke during the index event in an ethnically diverse Takotsubo cardiomyopathy population. Funct Neurol (2016) 0.75

Conventional Coronary Angiography Induced Takotsubo Cardiomyopathy Complicated with Cardiac Tamponade. Case Rep Cardiol (2017) 0.75

Microcirculatory dysfunction and autonomic disturbance in Takotsubo syndrome. Nat Rev Cardiol (2015) 0.75

Relative Lack of Culprit and Obstructive Coronary Lesions in Patients With Acute Ischemic Stroke and Elevated Cardiac Troponin. Circulation (2016) 0.75

Takotsubo cardiomyopathy: A potentially serious trap (Data from the International Takotsubo Cardiomyopathy Registry). Glob Cardiol Sci Pract (2015) 0.75

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome. PLoS One (2017) 0.75

DKA-Induced Takotsubo Cardiomyopathy in Patient with Known HOCM. Case Rep Crit Care (2017) 0.75

A case report of ventricular dysfunction post pericardiocentesis: stress cardiomyopathy or pericardial decompression syndrome? Cardiovasc Ultrasound (2015) 0.75

Use of cardiac MRI to diagnose Takotsubo syndrome. Nat Rev Cardiol (2015) 0.75

The natural history of takotsubo syndrome: a two-year follow-up study with myocardial sympathetic and perfusion G-SPECT imaging. Eur J Nucl Med Mol Imaging (2016) 0.75

Seasonal variation in patient characteristics and in-hospital outcomes of Takotsubo syndrome: a nationwide retrospective cohort study in Japan. Heart Vessels (2017) 0.75

Articles cited by this

(truncated to the top 100)

Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med (2005) 17.61

Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol (2001) 12.56

Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J (2006) 10.77

Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J (2008) 9.50

Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation (2006) 9.44

Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest (2007) 8.08

[Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases]. J Cardiol (1991) 7.95

Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation (2005) 6.85

Classification of the cardiomyopathies: a position statement from the European Society Of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J (2007) 6.34

Takotsubo cardiomyopathy: a new form of acute, reversible heart failure. Circulation (2008) 6.08

Stress (Takotsubo) cardiomyopathy--a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med (2008) 4.91

Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction. Am Heart J (2002) 4.90

Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome: A systematic review. Int J Cardiol (2007) 4.50

Echocardiographic correlates of acute heart failure, cardiogenic shock, and in-hospital mortality in tako-tsubo cardiomyopathy. JACC Cardiovasc Imaging (2014) 4.36

Clinical characteristics and cardiovascular magnetic resonance findings in stress (takotsubo) cardiomyopathy. JAMA (2011) 4.14

Apical ballooning of the left ventricle: first series in white patients. Heart (2003) 4.12

A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med (2008) 3.98

Guidelines for diagnosis of takotsubo (ampulla) cardiomyopathy. Circ J (2007) 3.82

Transient left ventricular apical ballooning in a community hospital in Germany. Int J Cardiol (2005) 3.45

Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. J Am Coll Cardiol (2009) 3.22

Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol (2003) 3.21

Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy. J Am Coll Cardiol (2010) 3.21

Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome. Am J Cardiol (2004) 3.19

Prevalence of Takotsubo cardiomyopathy in the United States. Am Heart J (2012) 3.15

The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase. Circ Res (2000) 2.99

Simple and accurate electrocardiographic criteria to differentiate takotsubo cardiomyopathy from anterior acute myocardial infarction. J Am Coll Cardiol (2010) 2.83

miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science (2010) 2.75

Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature. J Am Coll Cardiol (2000) 2.62

Electrocardiographic findings of takotsubo cardiomyopathy as compared with those of anterior acute myocardial infarction. J Electrocardiol (2014) 2.57

Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol (2007) 2.53

Increased responsiveness of left ventricular apical myocardium to adrenergic stimuli. Cardiovasc Res (1993) 2.31

Specific findings of the standard 12-lead ECG in patients with 'Takotsubo' cardiomyopathy: comparison with the findings of acute anterior myocardial infarction. Circ J (2003) 2.25

Revised clinical diagnostic criteria for Tako-tsubo syndrome: the Tako-tsubo Italian Network proposal. Int J Cardiol (2014) 2.17

Mechanisms of stress (Takotsubo) cardiomyopathy. Nat Rev Cardiol (2010) 2.13

Contrast echocardiography reveals apparently normal coronary perfusion in a rat model of stress-induced (Takotsubo) cardiomyopathy. Eur Heart J Cardiovasc Imaging (2013) 2.10

Pathophysiology of takotsubo syndrome: temporal phases of cardiovascular responses to extreme stress. Circ J (2014) 2.02

Clinical correlates and prognostic significance of electrocardiographic abnormalities in apical ballooning syndrome (Takotsubo/stress-induced cardiomyopathy). Am Heart J (2009) 2.01

Diagnostic utility of cardiac biomarkers in discriminating Takotsubo cardiomyopathy from acute myocardial infarction. J Card Fail (2013) 1.99

Prevalence and characteristics of left ventricular outflow tract obstruction in Tako-Tsubo syndrome. Am Heart J (2008) 1.93

Histological study on the distribution of autonomic nerves in the human heart. Heart Vessels (2003) 1.92

High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation (2012) 1.85

Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery. Eur Heart J (2007) 1.81

Comparison of the clinical characteristics of apical and non-apical variants of "broken heart" (takotsubo) syndrome in the United States. J Invasive Cardiol (2009) 1.79

Abnormalities in intracellular Ca2+ regulation contribute to the pathomechanism of Tako-Tsubo cardiomyopathy. Eur Heart J (2009) 1.78

17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circ Res (2004) 1.74

Sympathetic activity in patients with panic disorder at rest, under laboratory mental stress, and during panic attacks. Arch Gen Psychiatry (1998) 1.70

Natural history of tako-tsubo cardiomyopathy. Chest (2010) 1.70

Transient left ventricular apical ballooning: A unifying pathophysiologic theory at the edge of Prinzmetal angina. Catheter Cardiovasc Interv (2008) 1.69

Tako-Tsubo syndrome: an important differential diagnosis in patients with acute chest pain. Wien Klin Wochenschr (2010) 1.64

Activated cell survival cascade protects cardiomyocytes from cell death in Tako-Tsubo cardiomyopathy. Eur J Heart Fail (2009) 1.57

Stress-induced cardiomyopathy in Sweden: evidence for different ethnic predisposition and altered cardio-circulatory status. Cardiology (2012) 1.56

Clinical characteristics, ballooning pattern, and long-term prognosis of transient left ventricular ballooning syndrome. Heart Lung (2009) 1.52

Estrogen attenuates the emotional stress-induced cardiac responses in the animal model of Tako-tsubo (Ampulla) cardiomyopathy. J Cardiovasc Pharmacol (2003) 1.51

A single-centre report on the characteristics of Tako-tsubo syndrome. Heart Lung Circ (2009) 1.48

Transient apical ballooning syndrome--clinical characteristics, ballooning pattern, and long-term follow-up in a Swiss population. Int J Cardiol (2008) 1.48

Frequency and significance of myocardial bridging and recurrent segment of the left anterior descending coronary artery in patients with takotsubo cardiomyopathy. Am J Cardiol (2014) 1.46

Time course of electrocardiographic changes in patients with tako-tsubo syndrome: comparison with acute myocardial infarction with minimal enzymatic release. Circ J (2004) 1.45

J wave and fragmented QRS formation during the hyperacute phase in Takotsubo cardiomyopathy. Circ J (2014) 1.44

Transient left ventricular apical ballooning syndrome: a 4-year experience. J Cardiovasc Med (Hagerstown) (2008) 1.41

Impaired coronary microvascular reactivity in women with apical ballooning syndrome (Takotsubo/stress cardiomyopathy). Eur Heart J Acute Cardiovasc Care (2013) 1.21

Epinephrine activates both Gs and Gi pathways, but norepinephrine activates only the Gs pathway through human beta2-adrenoceptors overexpressed in mouse heart. Mol Pharmacol (2004) 1.21

Serial electrocardiographic findings in women with Takotsubo cardiomyopathy. Am J Cardiol (2007) 1.19

Stress cardiomyopathy. Annu Rev Med (2010) 1.15

Left ventricular apical ballooning syndrome: prevalence, clinical characteristics and pathogenetic mechanisms in a European population. Int J Cardiol (2008) 1.15

In-hospital mortality among patients with takotsubo cardiomyopathy: a study of the National Inpatient Sample 2008 to 2009. Am Heart J (2012) 1.14

Systematic review and meta-analysis of incidence and correlates of recurrence of takotsubo cardiomyopathy. Int J Cardiol (2014) 1.12

Chronic estrogen supplementation following ovariectomy improves the emotional stress-induced cardiovascular responses by indirect action on the nervous system and by direct action on the heart. Circ J (2007) 1.12

Reversible ventricular dysfunction takotsubo cardiomyopathy. Eur J Heart Fail (2005) 1.11

Novel rat model reveals important roles of β-adrenoreceptors in stress-induced cardiomyopathy. Int J Cardiol (2013) 1.11

L41Q polymorphism of the G protein coupled receptor kinase 5 is associated with left ventricular apical ballooning syndrome. Eur J Heart Fail (2010) 1.09

A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction. Eur Heart J (2013) 1.06

Clinical characteristics and four-year outcomes of patients in the Rhode Island Takotsubo Cardiomyopathy Registry. Am J Cardiol (2009) 1.06

Gender differences in the manifestation of tako-tsubo cardiomyopathy. Int J Cardiol (2011) 1.02

Outcomes of patients with stress-induced cardiomyopathy diagnosed by echocardiography in a tertiary referral hospital. J Am Soc Echocardiogr (2010) 0.98

Meta-analysis of clinical correlates of acute mortality in takotsubo cardiomyopathy. Am J Cardiol (2014) 0.97

Abnormal hippocampal BDNF and miR-16 expression is associated with depression-like behaviors induced by stress during early life. PLoS One (2012) 0.96

Complications in the clinical course of tako-tsubo cardiomyopathy. Int J Cardiol (2014) 0.95

Tako-tsubo syndrome and heart failure: long-term follow-up. Rev Esp Cardiol (Engl Ed) (2012) 0.93

Expression profiling of cardiac genes in Tako-Tsubo cardiomyopathy: insight into a new cardiac entity. J Mol Cell Cardiol (2007) 0.93

Estrogen reduces cardiac injury and expression of beta1-adrenoceptor upon ischemic insult in the rat heart. J Pharmacol Exp Ther (2004) 0.93

A new electrocardiographic criterion to differentiate between Takotsubo cardiomyopathy and anterior wall ST-segment elevation acute myocardial infarction. Am J Cardiol (2011) 0.92

Stress-induced cardiomyopathy: A review. Eur J Intern Med (2007) 0.92

Blockade of beta 1- and desensitization of beta 2-adrenoceptors reduce isoprenaline-induced cardiac fibrosis. Eur J Pharmacol (2004) 0.91

Molecular basis of disturbed extracellular matrix homeostasis in stress cardiomyopathy. Int J Cardiol (2013) 0.91

Different catecholamines induce different patterns of takotsubo-like cardiac dysfunction in an apparently afterload dependent manner. Int J Cardiol (2014) 0.90

Cardiostimulant and cardiodepressant effects through overexpressed human beta2-adrenoceptors in murine heart: regional differences and functional role of beta1-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.88

Clinical characteristics and outcome of left ventricular ballooning syndrome in a European population. Am J Cardiol (2011) 0.88

Acute myocardial infarction and stress cardiomyopathy following the Christchurch earthquakes. PLoS One (2013) 0.87

Usefulness of SUM of ST-segment elevation on electrocardiograms (limb leads) for predicting in-hospital complications in patients with stress (takotsubo) cardiomyopathy. Am J Cardiol (2012) 0.87

Observational study on Takotsubo-like cardiomyopathy: clinical features, diagnosis, prognosis and follow-up. BMJ Open (2012) 0.87

Cellular mechanisms underlying the cardiovascular actions of oestrogens. Clin Sci (Lond) (2006) 0.87

Clinical characteristics, sex hormones, and long-term follow-up in Swiss postmenopausal women presenting with Takotsubo cardiomyopathy. Clin Cardiol (2012) 0.87

Lack of efficacy of drug therapy in preventing takotsubo cardiomyopathy recurrence: a meta-analysis. Clin Cardiol (2014) 0.86

Gender-related differences in takotsubo cardiomyopathy. Heart Fail Clin (2013) 0.85

Performance of electrocardiographic criteria to differentiate Takotsubo cardiomyopathy from acute anterior ST elevation myocardial infarction. Int J Cardiol (2011) 0.85

Distinctive clinical characteristics according to age and gender in apical ballooning syndrome (takotsubo/stress cardiomyopathy): an analysis focusing on men and young women. J Card Fail (2013) 0.85

Takotsubo cardiomyopathy: an Australian single centre experience with medium term follow up. Intern Med J (2012) 0.85

Reduced sarcoplasmic reticulum Ca2+ -ATPase activity and dephosphorylated phospholamban contribute to contractile dysfunction in human hibernating myocardium. Mol Cell Biochem (2006) 0.84

Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle. Am J Physiol Heart Circ Physiol (2014) 0.83

Are the different patterns of stress-induced (Takotsubo) cardiomyopathy explained by regional mechanical overload and demand: supply mismatch in selected ventricular regions? Med Hypotheses (2013) 0.83

Articles by these authors

Use of cardiac MRI to diagnose Takotsubo syndrome. Nat Rev Cardiol (2015) 0.75

Microcirculatory dysfunction and autonomic disturbance in Takotsubo syndrome. Nat Rev Cardiol (2015) 0.75