Published in J Oncol on March 25, 2015
Pathologically decreased expression of miR-193a contributes to metastasis by targeting WT1-E-cadherin axis in non-small cell lung cancers. J Exp Clin Cancer Res (2016) 1.40
Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer. J Exp Clin Cancer Res (2016) 0.92
MiR-429 reverses epithelial-mesenchymal transition by restoring E-cadherin expression in bladder cancer. Oncotarget (2016) 0.90
New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies. Int J Mol Sci (2016) 0.86
The role of EMT and MET in cancer dissemination. Connect Tissue Res (2015) 0.84
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition. Oncotarget (2017) 0.82
The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer. Int J Mol Sci (2015) 0.81
MicroRNA aberrations: An emerging field for gallbladder cancer management. World J Gastroenterol (2016) 0.81
MicroRNAs and epithelial-mesenchymal transition in prostate cancer. Oncotarget (2016) 0.80
MicroRNA Regulation of Epithelial to Mesenchymal Transition. J Clin Med (2016) 0.80
miR-340 and ZEB1 negative feedback loop regulates TGF-β- mediated breast cancer progression. Oncotarget (2016) 0.79
Role of Bcl-2 and its associated miRNAs in vasculogenic mimicry of hepatocellular carcinoma. Int J Clin Exp Pathol (2015) 0.79
Notch in fibrosis and as a target of anti-fibrotic therapy. Pharmacol Res (2016) 0.79
Pre-miR-149 rs71428439 polymorphism is associated with increased cancer risk and AKT1/cyclinD1 signaling in hepatocellular carcinoma. Int J Clin Exp Med (2015) 0.78
Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer. Oncotarget (2016) 0.78
The relationship between vasculogenic mimicry and epithelial-mesenchymal transitions. J Cell Mol Med (2016) 0.77
microRNA-664 enhances proliferation, migration and invasion of lung cancer cells. Exp Ther Med (2017) 0.76
MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2. Aging (Albany NY) (2017) 0.76
MiR-124 effect in neurons apoptosis in newborn rat with thyroid hypofunction. Int J Clin Exp Pathol (2015) 0.76
Pancreatic cancer stem cell markers and exosomes - the incentive push. World J Gastroenterol (2016) 0.76
Cathepsin L upregulation-induced EMT phenotype is associated with the acquisition of cisplatin or paclitaxel resistance in A549 cells. Acta Pharmacol Sin (2016) 0.75
Molecular Mechanism of MicroRNA-200c Regulating Transforming Growth Factor-β (TGF-β)/SMAD Family Member 3 (SMAD3) Pathway by Targeting Zinc Finger E-Box Binding Homeobox 1 (ZEB1) in Hypospadias in Rats. Med Sci Monit (2016) 0.75
ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition. Oncotarget (2016) 0.75
A novel uPAg-KPI fusion protein inhibits the growth and invasion of human ovarian cancer cells in vitro. Int J Mol Med (2016) 0.75
MiR181c inhibits ovarian cancer metastasis and progression by targeting PRKCD expression. Int J Clin Exp Med (2015) 0.75
miRNA-200a/c as potential biomarker in epithelial ovarian cancer (EOC): evidence based on miRNA meta-signature and clinical investigations. Oncotarget (2016) 0.75
Epigenetic and miRNAs Dysregulation in Prostate Cancer: The role of Nutraceuticals. Anticancer Agents Med Chem (2016) 0.75
Diagnostic and prognostic value of plasma microRNA-195 in patients with non-small cell lung cancer. World J Surg Oncol (2016) 0.75
MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications. Dis Model Mech (2017) 0.75
ZEB1 Mediates Drug Resistance and EMT in p300-Deficient CRC. J Cancer (2017) 0.75
Tumor Microenvironment Modulation via Gold Nanoparticles Targeting Malicious Exosomes: Implications for Cancer Diagnostics and Therapy. Int J Mol Sci (2017) 0.75
MiR-139-5p as a novel serum biomarker for recurrence and metastasis in colorectal cancer. Sci Rep (2017) 0.75
Upregulation of MiR-205 under hypoxia promotes epithelial-mesenchymal transition by targeting ASPP2. Cell Death Dis (2016) 0.75
Re-expression of miR-200c suppresses proliferation, colony formation and in vivo tumor growth of murine claudin-low mammary tumor cells. Oncotarget (2017) 0.75
Members of the microRNA-200 family are promising therapeutic targets in cancer. Exp Ther Med (2017) 0.75
EMT: Present and future in clinical oncology. Mol Oncol (2017) 0.75
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
The genomic landscapes of human breast and colorectal cancers. Science (2007) 38.12
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (2008) 36.02
Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer (2002) 34.99
The basics of epithelial-mesenchymal transition. J Clin Invest (2009) 32.82
Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell (2003) 25.94
miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27
Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol (2006) 23.04
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature (2007) 21.53
Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell (2009) 18.31
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res (2006) 17.42
The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet (2010) 15.87
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev (2008) 15.01
Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol (2006) 13.12
Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci U S A (2005) 12.96
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep (2008) 10.71
microRNAs as oncogenes and tumor suppressors. Dev Biol (2006) 10.68
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem (2008) 10.08
Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol (2014) 10.04
TGF-beta and epithelial-to-mesenchymal transitions. Oncogene (2005) 10.02
Treatment of HCV infection by targeting microRNA. N Engl J Med (2013) 9.91
Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One (2008) 8.97
Biomarkers for epithelial-mesenchymal transitions. J Clin Invest (2009) 8.76
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol (2010) 6.67
Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol (2007) 6.11
Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov (2010) 6.07
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res (2009) 5.68
EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev (2009) 5.61
Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene (2005) 5.50
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res (2007) 5.25
Post-transcriptional gene silencing by siRNAs and miRNAs. Curr Opin Struct Biol (2005) 5.19
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A (2007) 4.92
MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle (2008) 4.81
Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. Cancer Res (2007) 4.65
Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol (2003) 4.53
MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol (2008) 4.45
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology (2008) 4.38
Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res (2009) 4.24
The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer? EMBO Rep (2010) 4.05
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res (2008) 4.04
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol (2010) 4.04
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol (2011) 3.85
p53 enters the microRNA world. Cancer Cell (2007) 3.78
Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res (2009) 3.76
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology (2006) 3.68
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev (2009) 3.58
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res (2009) 3.57
MicroRNAs and their regulatory roles in animals and plants. J Cell Physiol (2007) 3.38
Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res (2009) 3.30
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res (2010) 3.21
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions. Cell Cycle (2011) 3.15
Notch signaling. Clin Cancer Res (2006) 3.11
miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res (2009) 3.07
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med (2007) 3.05
miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. EMBO Rep (2009) 3.03
miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One (2009) 2.97
The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci (2009) 2.95
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med (2011) 2.93
miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet (2012) 2.89
Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest (2006) 2.68
miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells. Stem Cells (2009) 2.64
Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One (2010) 2.63
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev (2000) 2.62
Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes. Cell Cycle (2010) 2.61
The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies. J Mammary Gland Biol Neoplasia (2009) 2.60
Notch and cancer: a double-edged sword. Cell Mol Life Sci (2007) 2.59
Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF. Cancer Res (2010) 2.50
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell (2011) 2.49
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. Int J Cancer (2011) 2.49
Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res (2004) 2.45
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci U S A (2011) 2.45
Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res (2012) 2.45
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis (2007) 2.41
An updated overview on Wnt signaling pathways: a prelude for more. Circ Res (2010) 2.40
Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. J Mammary Gland Biol Neoplasia (2010) 2.38
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. EMBO J (2011) 2.29
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. Gynecol Oncol (2009) 2.26
Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity. J Cell Biol (2000) 2.12
uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells. J Cell Biol (2007) 2.11
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. J Biol Chem (2010) 2.05
miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells. J Biol Chem (2011) 1.98
Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature. Clin Exp Metastasis (2009) 1.94
Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas. Oncogene (2010) 1.93
MicroRNA expression analysis in triple-negative (ER, PR and Her2/neu) breast cancer. Cell Cycle (2011) 1.90
MicroRNA-204/211 alters epithelial physiology. FASEB J (2010) 1.83
Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. Int J Cancer (2010) 1.81
TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. Sci Signal (2011) 1.81
Cadherin-mediated cellular signaling. Curr Opin Cell Biol (2003) 1.80
E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells. Int J Cancer (2010) 1.78
The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness. Curr Drug Targets (2010) 1.75
MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biochem J (2011) 1.67
miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. Hepatology (2010) 1.66
First microRNA mimic enters clinic. Nat Biotechnol (2013) 1.65
A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene (2006) 1.62
Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation. Genome Res (2013) 1.59
MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer. Int J Cancer (2011) 1.58
Fractal dimensions of in vitro tumor cell proliferation. J Oncol (2015) 0.75
Current Perspectives in Cancer Immunotherapy. Cancers (Basel) (2019) 0.75